Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/48688 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovirus. Rio de Janeiro, RJ, Brasil. |
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Sousa Jr., Ivanildo P.Santos, Flavia B. dosPaula, Vanessa S. deVieira, Tuane C. R. G.Dias, Helver G.Barros, Caroline A.Silva, Edson E. da2021-08-20T14:38:19Z2021-08-20T14:38:19Z2021SOUSA JR, Ivanildo et al. Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil. Viruses, v. 13, 1370, p. 1-32, July 2021.1999-4915https://www.arca.fiocruz.br/handle/icict/4868810.3390/v13071370engMDPIEnterovírusFlavivírusAlfavírusHerpesvírusPrionSistema nervoso centralEnterovirusesFlavivirusesAlphavirusesHerpesvirusesPrionCentral nervous systemViral and Prion Infections Associated with Central Nervous System Syndromes in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovirus. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Bioquímica Médica Leopoldo de Meis. Instituto Nacional de Ciência e Tecnologia para Biologia Estrutural e Bioimagem. Programa de Biologia Estrutural,. Rio de Janeiro, RJ, Brasil / Instituto Federal do Rio de Janeiro. PMBqBM. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Bioquímica Médica Leopoldo de Meis. Instituto Nacional de Ciência e Tecnologia para Biologia Estrutural e Bioimagem. Programa de Biologia Estrutural,. Rio de Janeiro, RJ, Brasil / Instituto Federal do Rio de Janeiro. PMBqBM. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovirus. Rio de Janeiro, RJ, Brasil.Virus-induced infections of the central nervous system (CNS) are among the most serious problems in public health and can be associated with high rates of morbidity and mortality, mainly in low- and middle-income countries, where these manifestations have been neglected. Typically, herpes simplex virus 1 and 2, varicella-zoster, and enterovirus are responsible for a high number of cases in immunocompetent hosts, whereas other herpesviruses (for example, cytomegalovirus) are the most common in immunocompromised individuals. Arboviruses have also been associated with outbreaks with a high burden of neurological disorders, such as the Zika virus epidemic in Brazil. There is a current lack of understanding in Brazil about the most common viruses involved in CNS infections. In this review, we briefly summarize the most recent studies and findings associated with the CNS, in addition to epidemiological data that provide extensive information on the circulation and diversity of the most common neuro-invasive viruses in Brazil. We also highlight important aspects of the prion-associated diseases. This review provides readers with better knowledge of virus-associated CNS infections. A deeper understanding of these infections will support the improvement of the current surveillance strategies to allow the timely monitoring of the emergence/re-emergence of neurotropic viruses.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/48688/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALIvanildoSJr_EdsonSilva_etal_IOC_2021.pdfIvanildoSJr_EdsonSilva_etal_IOC_2021.pdfapplication/pdf3388306https://www.arca.fiocruz.br/bitstream/icict/48688/2/IvanildoSJr_EdsonSilva_etal_IOC_2021.pdfb416ae37fd59e75a93d4b5abab6e9ad3MD52TEXTIvanildoSJr_EdsonSilva_etal_IOC_2021.pdf.txtIvanildoSJr_EdsonSilva_etal_IOC_2021.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv |
Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil |
title |
Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil |
spellingShingle |
Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil Sousa Jr., Ivanildo P. Enterovírus Flavivírus Alfavírus Herpesvírus Prion Sistema nervoso central Enteroviruses Flaviviruses Alphaviruses Herpesviruses Prion Central nervous system |
title_short |
Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil |
title_full |
Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil |
title_fullStr |
Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil |
title_full_unstemmed |
Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil |
title_sort |
Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil |
author |
Sousa Jr., Ivanildo P. |
author_facet |
Sousa Jr., Ivanildo P. Santos, Flavia B. dos Paula, Vanessa S. de Vieira, Tuane C. R. G. Dias, Helver G. Barros, Caroline A. Silva, Edson E. da |
author_role |
author |
author2 |
Santos, Flavia B. dos Paula, Vanessa S. de Vieira, Tuane C. R. G. Dias, Helver G. Barros, Caroline A. Silva, Edson E. da |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Sousa Jr., Ivanildo P. Santos, Flavia B. dos Paula, Vanessa S. de Vieira, Tuane C. R. G. Dias, Helver G. Barros, Caroline A. Silva, Edson E. da |
dc.subject.other.pt_BR.fl_str_mv |
Enterovírus Flavivírus Alfavírus Herpesvírus Prion Sistema nervoso central |
topic |
Enterovírus Flavivírus Alfavírus Herpesvírus Prion Sistema nervoso central Enteroviruses Flaviviruses Alphaviruses Herpesviruses Prion Central nervous system |
dc.subject.en.pt_BR.fl_str_mv |
Enteroviruses Flaviviruses Alphaviruses Herpesviruses Prion Central nervous system |
description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovirus. Rio de Janeiro, RJ, Brasil. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-08-20T14:38:19Z |
dc.date.available.fl_str_mv |
2021-08-20T14:38:19Z |
dc.date.issued.fl_str_mv |
2021 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SOUSA JR, Ivanildo et al. Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil. Viruses, v. 13, 1370, p. 1-32, July 2021. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/48688 |
dc.identifier.issn.pt_BR.fl_str_mv |
1999-4915 |
dc.identifier.doi.none.fl_str_mv |
10.3390/v13071370 |
identifier_str_mv |
SOUSA JR, Ivanildo et al. Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil. Viruses, v. 13, 1370, p. 1-32, July 2021. 1999-4915 10.3390/v13071370 |
url |
https://www.arca.fiocruz.br/handle/icict/48688 |
dc.language.iso.fl_str_mv |
eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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MDPI |
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MDPI |
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