Low-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola

Detalhes bibliográficos
Autor(a) principal: Daniel, Elsa P. S. Kaingona
Data de Publicação: 2016
Outros Autores: Gomes, Larissa Rodrigues, Gama, Bianca E., Oliveira, Natália K. Almeida de, Fortes, Filomeno, Ménard, Didier, Daniel-Ribeiro, Cláudio Tadeu, Cruz, Maria de Fátima Ferreira da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/16540
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil / FIOCRUZ. Centro de Pesquisa, Diagnóstico e Treinamento em Malária (CPD-Mal) . Rio de Janeiro, RJ, Brasil / Hospital Central Dr. Antonio Agostinho Neto. Lubango, Angola / Health Progress and Investigation Network of the Portuguese-Speaking Countries Community (RIDESMal/CPLP). Lisbon, Portugal.
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spelling Daniel, Elsa P. S. KaingonaGomes, Larissa RodriguesGama, Bianca E.Oliveira, Natália K. Almeida deFortes, FilomenoMénard, DidierDaniel-Ribeiro, Cláudio TadeuCruz, Maria de Fátima Ferreira da2016-12-15T12:22:34Z2016-12-15T12:22:34Z2016DANIEL, Elsa P. S. Kaingona; et al. Low‑grade sulfadoxine–pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola. Malaria Journal, v.15:309, 6p, 2016.1475-2875https://www.arca.fiocruz.br/handle/icict/1654010.1186/s12936-016-1358-7engBioMed CentralMaláriaPirimetaminaSulfadoxinaPlasmodium falciparumAngolaMalariaP.falciparumpfdhfrpfdhpsSulfadoxinePyrimethamineAngolaLow-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angolainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil / FIOCRUZ. Centro de Pesquisa, Diagnóstico e Treinamento em Malária (CPD-Mal) . Rio de Janeiro, RJ, Brasil / Hospital Central Dr. Antonio Agostinho Neto. Lubango, Angola / Health Progress and Investigation Network of the Portuguese-Speaking Countries Community (RIDESMal/CPLP). Lisbon, Portugal.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil / FIOCRUZ. Centro de Pesquisa, Diagnóstico e Treinamento em Malária (CPD-Mal) . Rio de Janeiro, RJ, Brasil / Health Progress and Investigation Network of the Portuguese-Speaking Countries Community (RIDESMal/CPLP). Lisbon, Portugal.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil / Instituto Nacional de Câncer. Laboratório de Oncovirologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil / FIOCRUZ. Centro de Pesquisa, Diagnóstico e Treinamento em Malária (CPD-Mal) . Rio de Janeiro, RJ, Brasil / Health Progress and Investigation Network of the Portuguese-Speaking Countries Community (RIDESMal/CPLP). Lisbon, Portugal.National Institute of Public Health. Angolan National Malaria Control Programme. Luanda, Angola / Health Progress and Investigation Network of the Portuguese-Speaking Countries Community (RIDESMal/CPLP), Lisbon, Portugal.Institut Pasteur in Cambodia. Malaria Molecular Epidemiology Unit. Phnm Penh, Cambodia.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil / FIOCRUZ. Centro de Pesquisa, Diagnóstico e Treinamento em Malária (CPD-Mal) . Rio de Janeiro, RJ, Brasil / Health Progress and Investigation Network of the Portuguese-Speaking Countries Community (RIDESMal/CPLP). Lisbon, Portugal.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil / FIOCRUZ. Centro de Pesquisa, Diagnóstico e Treinamento em Malária (CPD-Mal) . Rio de Janeiro, RJ, Brasil / Health Progress and Investigation Network of the Portuguese-Speaking Countries Community (RIDESMal/CPLP). Lisbon, Portugal.Malaria is a major parasitic disease, affecting millions of people in endemic areas. Plasmodium falciparum parasites are responsible for the most severe cases and its resistance to anti-malarial drugs is notorious. This is a possible obstacle to the effectiveness of intermittent preventive treatment (IPT) based on sulfadoxine-pyrimethamine (SP) cures administrated to pregnant women (IPTp) during their pregnancy. As this intervention is recommended in Angola since 2006, it has assessed, in this country, the molecular profiles in P. falciparum dhfr and dhps, two polymorphic genes associated to pyrimethamine and sulfadoxine resistance, respectively.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/16540/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALlarissa_gomes_etal_IOC_2016.pdflarissa_gomes_etal_IOC_2016.pdfapplication/pdf1050672https://www.arca.fiocruz.br/bitstream/icict/16540/2/larissa_gomes_etal_IOC_2016.pdf08ec28e30080ca2f341202cc5f460572MD52TEXTlarissa_gomes_etal_IOC_2016.pdf.txtlarissa_gomes_etal_IOC_2016.pdf.txtExtracted texttext/plain34504https://www.arca.fiocruz.br/bitstream/icict/16540/3/larissa_gomes_etal_IOC_2016.pdf.txt008eff0a2076127861fcf57799f58a3bMD53icict/165402018-12-28 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dc.title.pt_BR.fl_str_mv Low-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola
title Low-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola
spellingShingle Low-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola
Daniel, Elsa P. S. Kaingona
Malária
Pirimetamina
Sulfadoxina
Plasmodium falciparum
Angola
Malaria
P.falciparum
pfdhfr
pfdhps
Sulfadoxine
Pyrimethamine
Angola
title_short Low-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola
title_full Low-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola
title_fullStr Low-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola
title_full_unstemmed Low-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola
title_sort Low-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola
author Daniel, Elsa P. S. Kaingona
author_facet Daniel, Elsa P. S. Kaingona
Gomes, Larissa Rodrigues
Gama, Bianca E.
Oliveira, Natália K. Almeida de
Fortes, Filomeno
Ménard, Didier
Daniel-Ribeiro, Cláudio Tadeu
Cruz, Maria de Fátima Ferreira da
author_role author
author2 Gomes, Larissa Rodrigues
Gama, Bianca E.
Oliveira, Natália K. Almeida de
Fortes, Filomeno
Ménard, Didier
Daniel-Ribeiro, Cláudio Tadeu
Cruz, Maria de Fátima Ferreira da
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Daniel, Elsa P. S. Kaingona
Gomes, Larissa Rodrigues
Gama, Bianca E.
Oliveira, Natália K. Almeida de
Fortes, Filomeno
Ménard, Didier
Daniel-Ribeiro, Cláudio Tadeu
Cruz, Maria de Fátima Ferreira da
dc.subject.other.pt_BR.fl_str_mv Malária
Pirimetamina
Sulfadoxina
Plasmodium falciparum
Angola
topic Malária
Pirimetamina
Sulfadoxina
Plasmodium falciparum
Angola
Malaria
P.falciparum
pfdhfr
pfdhps
Sulfadoxine
Pyrimethamine
Angola
dc.subject.en.pt_BR.fl_str_mv Malaria
P.falciparum
pfdhfr
pfdhps
Sulfadoxine
Pyrimethamine
Angola
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil / FIOCRUZ. Centro de Pesquisa, Diagnóstico e Treinamento em Malária (CPD-Mal) . Rio de Janeiro, RJ, Brasil / Hospital Central Dr. Antonio Agostinho Neto. Lubango, Angola / Health Progress and Investigation Network of the Portuguese-Speaking Countries Community (RIDESMal/CPLP). Lisbon, Portugal.
publishDate 2016
dc.date.accessioned.fl_str_mv 2016-12-15T12:22:34Z
dc.date.available.fl_str_mv 2016-12-15T12:22:34Z
dc.date.issued.fl_str_mv 2016
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv DANIEL, Elsa P. S. Kaingona; et al. Low‑grade sulfadoxine–pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola. Malaria Journal, v.15:309, 6p, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/16540
dc.identifier.issn.pt_BR.fl_str_mv 1475-2875
dc.identifier.doi.none.fl_str_mv 10.1186/s12936-016-1358-7
identifier_str_mv DANIEL, Elsa P. S. Kaingona; et al. Low‑grade sulfadoxine–pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola. Malaria Journal, v.15:309, 6p, 2016.
1475-2875
10.1186/s12936-016-1358-7
url https://www.arca.fiocruz.br/handle/icict/16540
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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