Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise

Detalhes bibliográficos
Autor(a) principal: Sarno, Manoel
Data de Publicação: 2016
Outros Autores: Sacramento, Gielson Almeida do, Cunha, Antonio Ricardo Khouri, Rosário, Mateus Santana do, Costa, Federico, Archanjo, Gracinda, Santos, Luciane Amorim, Nery Junior, Nivison Ruy Rocha, Vasilakis, Nikos, Ko, Albert Icksang, Almeida, Antonio R. P. de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/13665
Resumo: Hospital Geral Roberto Santos, Secretaria Estadual da Saúde da Bahia., Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil
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spelling Sarno, ManoelSacramento, Gielson Almeida doCunha, Antonio Ricardo KhouriRosário, Mateus Santana doCosta, FedericoArchanjo, GracindaSantos, Luciane AmorimNery Junior, Nivison Ruy RochaVasilakis, NikosKo, Albert IcksangAlmeida, Antonio R. P. de2016-04-08T19:37:02Z2016-04-08T19:37:02Z2016SARNO, M. et al. Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise. Plos Neglected Tropical Diseases, v. 10, n. 2, p. e0004517, 2016.1935-272710.1371/journal.pntd.0004517https://www.arca.fiocruz.br/handle/icict/13665engPublic Library of ScienceZika virusInfecçãoHidrocefaliaMicrocefaliaAmericasBrasilFemininoGravidezFetoHidropsia FetalMorte fetalSistema Nervoso CentralAbortoZika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demiseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHospital Geral Roberto Santos, Secretaria Estadual da Saúde da Bahia., Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilHospital Geral Roberto Santos, Secretaria Estadual da Saúde da Bahia., Salvador, BA, BrasilUniversidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, Connecticut, USAHospital Geral Roberto Santos, Secretaria Estadual da Saúde da Bahia., Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilThe University of Texas Medical Branch. Institute for Human Infections and Immunity. Department of Pathology and Center of Biodefense and Emerging Infectious Diseases. Galveston, Texas, USAFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, Connecticut, USAHospital Geral Roberto Santos, Secretaria Estadual da Saúde da Bahia., Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, BrasilThe rapid spread of Zika virus in the Americas and outbreak of microcephaly in Brazil has raised attention to the possible deleterious effects that the virus may have on fetuses. We report a case of a 20-year-old pregnant woman from Salvador, Brazil whose fetus had developed hydrops fetalis, a condition where there is abnormal accumulation of fluid in the fetus, as well as severe central nervous system defects such as microcephaly and hydranencephaly. After fetal demise, ZIKV RNA was detected in central nervous system tissues and amniotic fluid. The case report provides evidence that in addition to microcephaly, there may be a link between Zika virus infection and hydrops fetalis and fetal demise. Given the recent spread of the virus, systematic investigation of spontaneous abortions and stillbirths may be warranted to evaluate the risk that ZIKV infection imparts on these outcomes.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/13665/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSarno M Zika Virus Infection and Stillbirths....pdfSarno M Zika Virus Infection and Stillbirths....pdfapplication/pdf309667https://www.arca.fiocruz.br/bitstream/icict/13665/2/Sarno%20M%20Zika%20Virus%20Infection%20and%20Stillbirths....pdfbfc7d6ecd8b93b6ac4cee8fcc7cbc5d5MD52TEXTSarno M Zika Virus Infection and Stillbirths....pdf.txtSarno M Zika Virus Infection and Stillbirths....pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise
title Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise
spellingShingle Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise
Sarno, Manoel
Zika virus
Infecção
Hidrocefalia
Microcefalia
Americas
Brasil
Feminino
Gravidez
Feto
Hidropsia Fetal
Morte fetal
Sistema Nervoso Central
Aborto
title_short Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise
title_full Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise
title_fullStr Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise
title_full_unstemmed Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise
title_sort Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise
author Sarno, Manoel
author_facet Sarno, Manoel
Sacramento, Gielson Almeida do
Cunha, Antonio Ricardo Khouri
Rosário, Mateus Santana do
Costa, Federico
Archanjo, Gracinda
Santos, Luciane Amorim
Nery Junior, Nivison Ruy Rocha
Vasilakis, Nikos
Ko, Albert Icksang
Almeida, Antonio R. P. de
author_role author
author2 Sacramento, Gielson Almeida do
Cunha, Antonio Ricardo Khouri
Rosário, Mateus Santana do
Costa, Federico
Archanjo, Gracinda
Santos, Luciane Amorim
Nery Junior, Nivison Ruy Rocha
Vasilakis, Nikos
Ko, Albert Icksang
Almeida, Antonio R. P. de
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Sarno, Manoel
Sacramento, Gielson Almeida do
Cunha, Antonio Ricardo Khouri
Rosário, Mateus Santana do
Costa, Federico
Archanjo, Gracinda
Santos, Luciane Amorim
Nery Junior, Nivison Ruy Rocha
Vasilakis, Nikos
Ko, Albert Icksang
Almeida, Antonio R. P. de
dc.subject.other.pt_BR.fl_str_mv Zika virus
Infecção
Hidrocefalia
Microcefalia
Americas
Brasil
Feminino
Gravidez
Feto
Hidropsia Fetal
Morte fetal
Sistema Nervoso Central
Aborto
topic Zika virus
Infecção
Hidrocefalia
Microcefalia
Americas
Brasil
Feminino
Gravidez
Feto
Hidropsia Fetal
Morte fetal
Sistema Nervoso Central
Aborto
description Hospital Geral Roberto Santos, Secretaria Estadual da Saúde da Bahia., Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil
publishDate 2016
dc.date.accessioned.fl_str_mv 2016-04-08T19:37:02Z
dc.date.available.fl_str_mv 2016-04-08T19:37:02Z
dc.date.issued.fl_str_mv 2016
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SARNO, M. et al. Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise. Plos Neglected Tropical Diseases, v. 10, n. 2, p. e0004517, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/13665
dc.identifier.issn.none.fl_str_mv 1935-2727
10.1371/journal.pntd.0004517
identifier_str_mv SARNO, M. et al. Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise. Plos Neglected Tropical Diseases, v. 10, n. 2, p. e0004517, 2016.
1935-2727
10.1371/journal.pntd.0004517
url https://www.arca.fiocruz.br/handle/icict/13665
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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