Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil
| Autor(a) principal: | |
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| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/46784 |
Resumo: | A Rede Genômica Fiocruz é formada por especialistas de todas as unidades da Fundação no país e de institutos parceiros que se empenham diariamente em gerar dados mais robustos sobre o comportamento do SARS-Cov-2 e contribuir para um melhor preparo do país no enfrentamento da pandemia em termos de diagnóstico mais precisos e vacinas eficazes. Saiba mais sobre a Rede Genômica Fiocruz em: http://www.genomahcov.fiocruz.br/ |
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Resende, Paola CristinaDelatorre, EdsonGräf, TiagoMir, DaianaMotta, Fernando CoutoAppolinario, Luciana ReisPaixão, Anna Carolina Dias daMendonça, Ana Carolina da FonsecaOgrzewalska, MariaCaetano, BrauliaWallau, Gabriel LuzDocena, CássiaSantos, Mirleide Cordeiro dosFerreira, Jessylene de AlmeidaSousa Junior, Edivaldo CostaSilva, Sandro Patroca daFernandes, Sandra BianchiniVianna, Lucas AlvesSouza, Larissa da CostaFerro, Jean F. G.Nardy, Vanessa B.Santos, Cliomar A.Riediger, Irina NastassjaDebur, Maria do CarmoCroda, JúlioOliveira, Wanderson K.Abreu, Andre Luiz deBello, GonzaloSiqueira, Marilda Agudo Mendonça Teixeira de2021-04-20T13:27:56Z2021-04-20T13:27:56Z2021RESENDE, Paola Cristina et al. Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil. Frontiers in Microbioiology, v. 11, p. 1-14, 17 Fev. 2021.1664-302Xhttps://www.arca.fiocruz.br/handle/icict/4678410.3389/fmicb.2020.615280A Rede Genômica Fiocruz é formada por especialistas de todas as unidades da Fundação no país e de institutos parceiros que se empenham diariamente em gerar dados mais robustos sobre o comportamento do SARS-Cov-2 e contribuir para um melhor preparo do país no enfrentamento da pandemia em termos de diagnóstico mais precisos e vacinas eficazes. Saiba mais sobre a Rede Genômica Fiocruz em: http://www.genomahcov.fiocruz.br/CGLab/MoH (General Laboratories Coordination of Brazilian Ministry of Health)CVSLR/FIOCRUZ (Coordination of Health Surveillance and Reference Laboratories of Oswaldo Cruz Foundation)CNPq COVID-19 MCTI 402457/2020-0INOVA VPPCB-005-FIO-20-2Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Universidade Federal do Espírito Santo. Centro de Ciências Exatas, Naturais e da Saúde. Departamento de Biologia. Alegre, ES, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Universidad de la Republica. Centro Universitario Regional del Litoral Norte. Unidad de Genomica y Bioinformatica. Salto, Uruguay.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Instituto Evandro Chagas. Belém, PA, Brasil.Instituto Evandro Chagas. Belém, PA, Brasil.Instituto Evandro Chagas. Belém, PA, Brasil.Instituto Evandro Chagas. Belém, PA, Brasil.Laboratório Central de Saúde Pública do Estado de Santa Catarina. Florianópolis, SC, Brasil.Laboratório Central de Saúde Pública do Estado Espírito Santo. Vitória, ES, Brasil.Laboratório Central de Saúde Pública do Distrito Federal. Brasília, DF, Brasil.Laboratório Central de Saúde Pública de Alagoas. Maceió, AL, Brasil.Laboratório Central de Saúde Pública da Bahia. Salvador, BA, Brasil.Laboratório Central de Saúde Pública de Sergipe. Aracaju, SE, Brasil.Laboratório Central de Saúde Pública do Paraná. Curitiba, PR, Brasil.Laboratório Central de Saúde Pública do Paraná. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Fiocruz Mato Grosso do Sul. Campo Grande, MS, Brasil / Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brasil.Ministério da Defesa. Hospital das Forças Armadas. Brasília, DF, Brasil.Ministério da Saúde. Coordenadoria Geral de Laboratórios. Brasília, DF, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.A previous study demonstrates that most of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Brazilian strains fell in three local clades that were introduced from Europe around late February 2020. Here we investigated in more detail the origin of the major and most widely disseminated SARS-CoV-2 Brazilian lineage B.1.1.33. We recovered 190 whole viral genomes collected from 13 Brazilian states from February 29 to April 31, 2020 and combined them with other B.1.1 genomes collected globally. Our genomic survey confirms that lineage B.1.1.33 is responsible for a variable fraction of the community viral transmissions in Brazilian states, ranging from 2% of all SARS-CoV-2 genomes from Pernambuco to 80% of those from Rio de Janeiro. We detected a moderate prevalence (5–18%) of lineage B.1.1.33 in some South American countries and a very low prevalence (<1%) in North America, Europe, and Oceania. Our study reveals that lineage B.1.1.33 evolved from an ancestral clade, here designated B.1.1.33-like, that carries one of the two B.1.1.33 synapomorphic mutations. The B.1.1.33-like lineage may have been introduced from Europe or arose in Brazil in early February 2020 and a few weeks later gave origin to the lineage B.1.1.33. These SARS-CoV-2 lineages probably circulated during February 2020 and reached all Brazilian regions and multiple countries around the world by mid-March, before the implementation of air travel restrictions in Brazil. Our phylodynamic analysis also indicates that public health interventions were partially effective to control the expansion of lineage B.1.1.33 in Rio de Janeiro because its median effective reproductive number (Re) was drastically reduced by about 66% during March 2020, but failed to bring it to below one. Continuous genomic surveillance of lineage B.1.1.33 might provide valuable information about epidemic dynamics and the effectiveness of public health interventions in some Brazilian states.engFrontiers MediaCOVID-19SARS-CoV-2BetacoronavirusCoronavírusBrasilSíndrome Respiratória Aguda GraveGenoma viralRede Genômica FiocruzGENOMAHCOVCoronavirus disease 2019Severe acute respiratory syndrome coronavirus-2CoronavirusBrazilGenetic lineagesCommunity transmissionEvolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/46784/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALResende, Paola Cristina 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| dc.title.en.fl_str_mv |
Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil |
| title |
Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil |
| spellingShingle |
Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil Resende, Paola Cristina COVID-19 SARS-CoV-2 Betacoronavirus Coronavírus Brasil Síndrome Respiratória Aguda Grave Genoma viral Rede Genômica Fiocruz GENOMAHCOV Coronavirus disease 2019 Severe acute respiratory syndrome coronavirus-2 Coronavirus Brazil Genetic lineages Community transmission |
| title_short |
Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil |
| title_full |
Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil |
| title_fullStr |
Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil |
| title_full_unstemmed |
Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil |
| title_sort |
Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil |
| author |
Resende, Paola Cristina |
| author_facet |
Resende, Paola Cristina Delatorre, Edson Gräf, Tiago Mir, Daiana Motta, Fernando Couto Appolinario, Luciana Reis Paixão, Anna Carolina Dias da Mendonça, Ana Carolina da Fonseca Ogrzewalska, Maria Caetano, Braulia Wallau, Gabriel Luz Docena, Cássia Santos, Mirleide Cordeiro dos Ferreira, Jessylene de Almeida Sousa Junior, Edivaldo Costa Silva, Sandro Patroca da Fernandes, Sandra Bianchini Vianna, Lucas Alves Souza, Larissa da Costa Ferro, Jean F. G. Nardy, Vanessa B. Santos, Cliomar A. Riediger, Irina Nastassja Debur, Maria do Carmo Croda, Júlio Oliveira, Wanderson K. Abreu, Andre Luiz de Bello, Gonzalo Siqueira, Marilda Agudo Mendonça Teixeira de |
| author_role |
author |
| author2 |
Delatorre, Edson Gräf, Tiago Mir, Daiana Motta, Fernando Couto Appolinario, Luciana Reis Paixão, Anna Carolina Dias da Mendonça, Ana Carolina da Fonseca Ogrzewalska, Maria Caetano, Braulia Wallau, Gabriel Luz Docena, Cássia Santos, Mirleide Cordeiro dos Ferreira, Jessylene de Almeida Sousa Junior, Edivaldo Costa Silva, Sandro Patroca da Fernandes, Sandra Bianchini Vianna, Lucas Alves Souza, Larissa da Costa Ferro, Jean F. G. Nardy, Vanessa B. Santos, Cliomar A. Riediger, Irina Nastassja Debur, Maria do Carmo Croda, Júlio Oliveira, Wanderson K. Abreu, Andre Luiz de Bello, Gonzalo Siqueira, Marilda Agudo Mendonça Teixeira de |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Resende, Paola Cristina Delatorre, Edson Gräf, Tiago Mir, Daiana Motta, Fernando Couto Appolinario, Luciana Reis Paixão, Anna Carolina Dias da Mendonça, Ana Carolina da Fonseca Ogrzewalska, Maria Caetano, Braulia Wallau, Gabriel Luz Docena, Cássia Santos, Mirleide Cordeiro dos Ferreira, Jessylene de Almeida Sousa Junior, Edivaldo Costa Silva, Sandro Patroca da Fernandes, Sandra Bianchini Vianna, Lucas Alves Souza, Larissa da Costa Ferro, Jean F. G. Nardy, Vanessa B. Santos, Cliomar A. Riediger, Irina Nastassja Debur, Maria do Carmo Croda, Júlio Oliveira, Wanderson K. Abreu, Andre Luiz de Bello, Gonzalo Siqueira, Marilda Agudo Mendonça Teixeira de |
| dc.subject.other.pt_BR.fl_str_mv |
COVID-19 SARS-CoV-2 Betacoronavirus Coronavírus Brasil Síndrome Respiratória Aguda Grave Genoma viral Rede Genômica Fiocruz GENOMAHCOV |
| topic |
COVID-19 SARS-CoV-2 Betacoronavirus Coronavírus Brasil Síndrome Respiratória Aguda Grave Genoma viral Rede Genômica Fiocruz GENOMAHCOV Coronavirus disease 2019 Severe acute respiratory syndrome coronavirus-2 Coronavirus Brazil Genetic lineages Community transmission |
| dc.subject.en.en.fl_str_mv |
Coronavirus disease 2019 Severe acute respiratory syndrome coronavirus-2 Coronavirus Brazil Genetic lineages Community transmission |
| description |
A Rede Genômica Fiocruz é formada por especialistas de todas as unidades da Fundação no país e de institutos parceiros que se empenham diariamente em gerar dados mais robustos sobre o comportamento do SARS-Cov-2 e contribuir para um melhor preparo do país no enfrentamento da pandemia em termos de diagnóstico mais precisos e vacinas eficazes. Saiba mais sobre a Rede Genômica Fiocruz em: http://www.genomahcov.fiocruz.br/ |
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2021 |
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2021-04-20T13:27:56Z |
| dc.date.available.fl_str_mv |
2021-04-20T13:27:56Z |
| dc.date.issued.fl_str_mv |
2021 |
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info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.citation.fl_str_mv |
RESENDE, Paola Cristina et al. Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil. Frontiers in Microbioiology, v. 11, p. 1-14, 17 Fev. 2021. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/46784 |
| dc.identifier.issn.pt_BR.fl_str_mv |
1664-302X |
| dc.identifier.doi.pt_BR.fl_str_mv |
10.3389/fmicb.2020.615280 |
| identifier_str_mv |
RESENDE, Paola Cristina et al. Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil. Frontiers in Microbioiology, v. 11, p. 1-14, 17 Fev. 2021. 1664-302X 10.3389/fmicb.2020.615280 |
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https://www.arca.fiocruz.br/handle/icict/46784 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Frontiers Media |
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Frontiers Media |
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reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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FIOCRUZ |
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Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/46784/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/46784/2/Resende%2c%20Paola%20Cristina%20Evolutionary....pdf https://www.arca.fiocruz.br/bitstream/icict/46784/4/_AUTORIZACAO_DEPOSITO_ARCA_REDE_GENOMICA.pdf https://www.arca.fiocruz.br/bitstream/icict/46784/3/Resende%2c%20Paola%20Cristina%20Evolutionary....pdf.txt |
| bitstream.checksum.fl_str_mv |
36b51ef91c52b5338d9d29ba0cc807bc aa487e7239ef3ade32eeb6eec0f2c3cc 28ef5cd96257018f624857e2ce8ab529 0515fca7e111ed7c72668196e0a1d2be |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1813008880178823168 |