Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2009 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/39088 |
Resumo: | Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Núcleo de Pesquisas de Produtos Naturais. Rio de Janeiro, RJ, Brasil. |
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Pinto, Shaft CorrêaLeitão, Gilda GuimarãesOliveira, Danilo Ribeiro deBizzo, Humberto RibeiroRamos, Daniela FernandesCoelho, Tatiane SilveiraSilva, Pedro Eduardo A.Lourenço, Maria Cristina S.Leitão, Suzana Guimarães2020-01-09T14:23:43Z2020-01-09T14:23:43Z2009PINTO, Shaft Corrêa et al. Chemical Composition and Antimycobacterial Activity of the Essential Oil from Anemia tomentosa var. anthriscifolia. Natural Product Communications, v. 4, n. 12, p. 1675-1678, 2009.1934-578Xhttps://www.arca.fiocruz.br/handle/icict/3908810.1177/1934578X09004012131555-9475engSAGE PublicationsChemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifoliainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Núcleo de Pesquisas de Produtos Naturais. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Núcleo de Pesquisas de Produtos Naturais. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Núcleo de Pesquisas de Produtos Naturais. Rio de Janeiro, RJ, Brasil.Embrapa Agroindústria de Alimentos. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio Grande. Laboratório de Micobactérias. Rio Grande, RS, Brasil .Universidade Federal do Rio Grande. Laboratório de Micobactérias. Rio Grande, RS, Brasil .Universidade Federal do Rio Grande. Laboratório de Micobactérias. Rio Grande, RS, Brasil .Fundação Oswaldo Cruz.Instituto de Pesquisa Clínica Evandro Chagas. Plataforma de Bioensaios II. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Faculdade de Farmácia. Departamento de Produtos Naturais e Alimentos. Rio de Janeiro, RJ, Brasil.The essential oil from Anemia tomentosa var. anthriscifolia showed in vitro activity against Mycobacterium tuberculosis (MIC 100 μg/ml) and therefore was characterized by gas chromatography (GC) and by gas chromatography coupled with mass spectrometry (GC-MS). The major constituents of this essential oil were triquinane sesquiterpenes: silphiperfol-6-ene (14.7%), (–)-epi-presilphiperfolan-1-ol (30.6%), presilphiperfol-7-ene (3.9%), cameroonan-7α-ol (4.4%), prenopsan-8-ol (1.9%) and presilphiperfolan-8-ol (8.3%), suggesting the existence of different chemotypes for this species. The essential oil was fractionated by column chromatography and its major constituent and fractions were assayed against Mycobacterium tuberculosis and M. smegmatis. (–)-epi-Presilphiperfolan-1-ol exhibited an MIC of 120 μg/ml against M. tuberculosis H37Rv.Anemia tomentosaTriquinane sesquiterpenesMycobacterium tuberculosisPteridophytaTuberculosisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/39088/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Pinto_Shaft_etal_INI_2009.pdfve_Pinto_Shaft_etal_INI_2009.pdfapplication/pdf226907https://www.arca.fiocruz.br/bitstream/icict/39088/2/ve_Pinto_Shaft_etal_INI_2009.pdfe140b3e9ac4a344b679551c780ec157bMD52TEXTve_Pinto_Shaft_etal_INI_2009.pdf.txtve_Pinto_Shaft_etal_INI_2009.pdf.txtExtracted texttext/plain20196https://www.arca.fiocruz.br/bitstream/icict/39088/3/ve_Pinto_Shaft_etal_INI_2009.pdf.txtf8c23a31d83f80b44e495093325469f8MD53icict/390882020-01-10 02:02:21.922oai:www.arca.fiocruz.br:icict/39088Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352020-01-10T05:02:21Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia |
| title |
Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia |
| spellingShingle |
Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia Pinto, Shaft Corrêa Anemia tomentosa Triquinane sesquiterpenes Mycobacterium tuberculosis Pteridophyta Tuberculosis |
| title_short |
Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia |
| title_full |
Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia |
| title_fullStr |
Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia |
| title_full_unstemmed |
Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia |
| title_sort |
Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia |
| author |
Pinto, Shaft Corrêa |
| author_facet |
Pinto, Shaft Corrêa Leitão, Gilda Guimarães Oliveira, Danilo Ribeiro de Bizzo, Humberto Ribeiro Ramos, Daniela Fernandes Coelho, Tatiane Silveira Silva, Pedro Eduardo A. Lourenço, Maria Cristina S. Leitão, Suzana Guimarães |
| author_role |
author |
| author2 |
Leitão, Gilda Guimarães Oliveira, Danilo Ribeiro de Bizzo, Humberto Ribeiro Ramos, Daniela Fernandes Coelho, Tatiane Silveira Silva, Pedro Eduardo A. Lourenço, Maria Cristina S. Leitão, Suzana Guimarães |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Pinto, Shaft Corrêa Leitão, Gilda Guimarães Oliveira, Danilo Ribeiro de Bizzo, Humberto Ribeiro Ramos, Daniela Fernandes Coelho, Tatiane Silveira Silva, Pedro Eduardo A. Lourenço, Maria Cristina S. Leitão, Suzana Guimarães |
| dc.subject.en.pt_BR.fl_str_mv |
Anemia tomentosa Triquinane sesquiterpenes Mycobacterium tuberculosis Pteridophyta Tuberculosis |
| topic |
Anemia tomentosa Triquinane sesquiterpenes Mycobacterium tuberculosis Pteridophyta Tuberculosis |
| description |
Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Núcleo de Pesquisas de Produtos Naturais. Rio de Janeiro, RJ, Brasil. |
| publishDate |
2009 |
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2009 |
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2020-01-09T14:23:43Z |
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2020-01-09T14:23:43Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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| dc.identifier.citation.fl_str_mv |
PINTO, Shaft Corrêa et al. Chemical Composition and Antimycobacterial Activity of the Essential Oil from Anemia tomentosa var. anthriscifolia. Natural Product Communications, v. 4, n. 12, p. 1675-1678, 2009. |
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https://www.arca.fiocruz.br/handle/icict/39088 |
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1934-578X |
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10.1177/1934578X0900401213 |
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1555-9475 |
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PINTO, Shaft Corrêa et al. Chemical Composition and Antimycobacterial Activity of the Essential Oil from Anemia tomentosa var. anthriscifolia. Natural Product Communications, v. 4, n. 12, p. 1675-1678, 2009. 1934-578X 10.1177/1934578X0900401213 1555-9475 |
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SAGE Publications |
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SAGE Publications |
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