Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.3390/jcm6080078 |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/29749 |
Resumo: | University of Witwatersrand. Faculty of Health Sciences. School of Clinical Medicine. Department of Internal Medicine. Clinical HIV Research Unit. Johannesburg, South Africa. |
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Badal-Faesen, SharlaaFirnhaber, CynthiaKendall, Michelle A.Wu, XingyeGrinsztejn, BeatrizEscada, Rodrigo Otavio da SilvaFernandez, MichelHogg, EvelynSanne, IanJohnson, PamelaAlland, DavidMazurek, Gerald H.Benator, Debra A.Luetkemeyer, Anne F.AIDS Clinical Trials Group A5295Tuberculosis Trials Consortium Study 34 Teams2018-10-26T14:38:32Z2018-10-26T14:38:32Z2017BADAL-FAESEN, Sharlaa et al. Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis. Journal of Clinical Medicine, v. 6, n. 8, p. 1-4, 2017.2077-0383https://www.arca.fiocruz.br/handle/icict/2974910.3390/jcm6080078engImpact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversity of Witwatersrand. Faculty of Health Sciences. School of Clinical Medicine. Department of Internal Medicine. Clinical HIV Research Unit. Johannesburg, South Africa.University of Witwatersrand. Faculty of Health Sciences. School of Clinical Medicine. Department of Internal Medicine. Clinical HIV Research Unit. Johannesburg, South Africa.Chan School of Public Health Boston. Harvard T.H. Center for Biostatistics in AIDS Research. Boston, MA, USA.Chan School of Public Health Boston. Harvard T.H. Center for Biostatistics in AIDS Research. Boston, MA, USA.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.Baylor Scott and White Hospital. Pulmonary and Critical Care Department. Temple, TX, USA.Social & Scientific Systems, Inc. Silver Spring, MD, USA.University of Witwatersrand. Faculty of Health Sciences. School of Clinical Medicine. Department of Internal Medicine. Clinical HIV Research Unit. Johannesburg, South Africa.Cepheid Inc. Sunnyvale, CA, USA.Rutgers-New Jersey Medical School. Division of Infectious Disease. Newark, NJ, USA.Centers for Disease Control and Prevention. Division of Tuberculosis Elimination. Atlanta, GA, USA.The George Washington University. The Veterans Affairs Medical Center. Washington, DC, USA.University of California. Zuckerberg San Francisco General. Infectious Diseases and Global Medicine. Division of HIV. San Francisco, CA, USA.University of Witwatersrand. Faculty of Health Sciences. School of Clinical Medicine. Department of Internal Medicine. Clinical HIV Research Unit. Johannesburg, South Africa.University of Witwatersrand. Faculty of Health Sciences. School of Clinical Medicine. Department of Internal Medicine. Clinical HIV Research Unit. Johannesburg, South Africa.As a strategy to improve the sensitivity of nucleic acid-based testing in acid-fast bacilli (AFB) negative samples, larger volumes of sputum (5-10 mL) were tested with Xpert® MTB/RIF from 176 individuals with smear-negative sputum undergoing tuberculosis evaluation. Despite larger volumes, this strategy had a suboptimal sensitivity of 50% (4/8).Xpert MTB/RIFLarger volume sputumSmear-negative suspectsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALve_Sharlaa_Badal-Faesen_etal_INI_Lapclin_2017.pdfve_Sharlaa_Badal-Faesen_etal_INI_Lapclin_2017.pdfapplication/pdf205013https://www.arca.fiocruz.br/bitstream/icict/29749/2/ve_Sharlaa_Badal-Faesen_etal_INI_Lapclin_2017.pdf947db24e3b2bfe3bc5258c5c275137ddMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/29749/3/license.txt5a560609d32a3863062d77ff32785d58MD53TEXTve_Sharlaa_Badal-Faesen_etal_INI_Lapclin_2017.pdf.txtve_Sharlaa_Badal-Faesen_etal_INI_Lapclin_2017.pdf.txtExtracted texttext/plain16256https://www.arca.fiocruz.br/bitstream/icict/29749/4/ve_Sharlaa_Badal-Faesen_etal_INI_Lapclin_2017.pdf.txt1ceaf6bcaf35ff32309ecd7ca5548f99MD54icict/297492019-08-09 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| dc.title.pt_BR.fl_str_mv |
Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis |
| title |
Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis |
| spellingShingle |
Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis Badal-Faesen, Sharlaa Xpert MTB/RIF Larger volume sputum Smear-negative suspects |
| title_short |
Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis |
| title_full |
Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis |
| title_fullStr |
Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis |
| title_full_unstemmed |
Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis |
| title_sort |
Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis |
| author |
Badal-Faesen, Sharlaa |
| author_facet |
Badal-Faesen, Sharlaa Firnhaber, Cynthia Kendall, Michelle A. Wu, Xingye Grinsztejn, Beatriz Escada, Rodrigo Otavio da Silva Fernandez, Michel Hogg, Evelyn Sanne, Ian Johnson, Pamela Alland, David Mazurek, Gerald H. Benator, Debra A. Luetkemeyer, Anne F. AIDS Clinical Trials Group A5295 Tuberculosis Trials Consortium Study 34 Teams |
| author_role |
author |
| author2 |
Firnhaber, Cynthia Kendall, Michelle A. Wu, Xingye Grinsztejn, Beatriz Escada, Rodrigo Otavio da Silva Fernandez, Michel Hogg, Evelyn Sanne, Ian Johnson, Pamela Alland, David Mazurek, Gerald H. Benator, Debra A. Luetkemeyer, Anne F. AIDS Clinical Trials Group A5295 Tuberculosis Trials Consortium Study 34 Teams |
| author2_role |
author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Badal-Faesen, Sharlaa Firnhaber, Cynthia Kendall, Michelle A. Wu, Xingye Grinsztejn, Beatriz Escada, Rodrigo Otavio da Silva Fernandez, Michel Hogg, Evelyn Sanne, Ian Johnson, Pamela Alland, David Mazurek, Gerald H. Benator, Debra A. Luetkemeyer, Anne F. AIDS Clinical Trials Group A5295 Tuberculosis Trials Consortium Study 34 Teams |
| dc.subject.en.pt_BR.fl_str_mv |
Xpert MTB/RIF Larger volume sputum Smear-negative suspects |
| topic |
Xpert MTB/RIF Larger volume sputum Smear-negative suspects |
| description |
University of Witwatersrand. Faculty of Health Sciences. School of Clinical Medicine. Department of Internal Medicine. Clinical HIV Research Unit. Johannesburg, South Africa. |
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2017 |
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2017 |
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2018-10-26T14:38:32Z |
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2018-10-26T14:38:32Z |
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BADAL-FAESEN, Sharlaa et al. Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis. Journal of Clinical Medicine, v. 6, n. 8, p. 1-4, 2017. |
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2077-0383 |
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10.3390/jcm6080078 |
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BADAL-FAESEN, Sharlaa et al. Impact of Larger Sputum Volume on Xpert® MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis. Journal of Clinical Medicine, v. 6, n. 8, p. 1-4, 2017. 2077-0383 10.3390/jcm6080078 |
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