Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/50470 |
Resumo: | Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
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Penetra, Stephanie L. S.Silva, Michele F. B. daResende, PaolaPina-Costa, AnielleSantos, Heloisa F. P.Guaraldo, LusieleCalvet, Guilherme A.Ogrzewalska, MariaArantes, IghorZukeram, KetiuceAraújo, Mia F. deLima, Ana Beatriz MachadoLopes, Renata SerranoLira-Silva, Larissa R.Moraes, Isabella V.Wakimoto, Mayumi D.Fuller, Trevon L.Gabaglia, Claudia RajaEspíndola, Otávio M.Bonaldo, Myrna C.Daniel-Ribeiro, Cláudio TadeuWhitworth, JimmySmith, ChrisNielsen-Saines, KarinPauvolid-Correa, AlexSiqueira, Marilda Agudo Mendonça Teixeira deBrasil, Patricia2021-12-17T12:11:10Z2021-12-17T12:11:10Z2021PENETRA, Stephanie L. S. et al. Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil. International Journal of Infectious Diseases, v. 114, p. 58-61, 2021.1201-9712https://www.arca.fiocruz.br/handle/icict/5047010.1016/j.ijid.2021.10.048Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Fundação de Educação Serra dos Órgãos, Teresópolis, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / University of California. Los Angeles, CA, USA.Biomedical Research Institute of Southern California. Oceanside, CA, USA.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.London School of Hygiene and Tropical Medicine. Department of Clinical Research. London, United Kingdom.London School of Hygiene and Tropical Medicine. Department of Clinical Research. London, United Kingdom.University of California. Los Angeles, CA, USA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.We describe a case of prolonged COVID-19 caused by the SARS-CoV-2 Gamma variant in a fully vaccinated healthcare worker, 387 days after an infection caused by lineage B.1.1.33. Infections were confirmed by whole-genome sequencing and corroborated by the detection of neutralizing antibodies in convalescent serum samples. Considering the permanent exposure of this healthcare worker to SARS-CoV-2, the waning immunity after the first infection, the low efficacy of the inactivated vaccine at preventing COVID-19, the immune escape of the Gamma variant (VOC), and the burden of post-COVID syndrome, this individual would have benefited from an additional dose of a heterologous vaccine.engElsevierPost-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCOVID-19SARS-CoV-2 variantsHealth personnelPost-acute syndromeReinfectionWhole-genome sequencingBreakthrough infectioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv |
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil |
title |
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil |
spellingShingle |
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil Penetra, Stephanie L. S. COVID-19 SARS-CoV-2 variants Health personnel Post-acute syndrome Reinfection Whole-genome sequencing Breakthrough infection |
title_short |
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil |
title_full |
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil |
title_fullStr |
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil |
title_full_unstemmed |
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil |
title_sort |
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil |
author |
Penetra, Stephanie L. S. |
author_facet |
Penetra, Stephanie L. S. Silva, Michele F. B. da Resende, Paola Pina-Costa, Anielle Santos, Heloisa F. P. Guaraldo, Lusiele Calvet, Guilherme A. Ogrzewalska, Maria Arantes, Ighor Zukeram, Ketiuce Araújo, Mia F. de Lima, Ana Beatriz Machado Lopes, Renata Serrano Lira-Silva, Larissa R. Moraes, Isabella V. Wakimoto, Mayumi D. Fuller, Trevon L. Gabaglia, Claudia Raja Espíndola, Otávio M. Bonaldo, Myrna C. Daniel-Ribeiro, Cláudio Tadeu Whitworth, Jimmy Smith, Chris Nielsen-Saines, Karin Pauvolid-Correa, Alex Siqueira, Marilda Agudo Mendonça Teixeira de Brasil, Patricia |
author_role |
author |
author2 |
Silva, Michele F. B. da Resende, Paola Pina-Costa, Anielle Santos, Heloisa F. P. Guaraldo, Lusiele Calvet, Guilherme A. Ogrzewalska, Maria Arantes, Ighor Zukeram, Ketiuce Araújo, Mia F. de Lima, Ana Beatriz Machado Lopes, Renata Serrano Lira-Silva, Larissa R. Moraes, Isabella V. Wakimoto, Mayumi D. Fuller, Trevon L. Gabaglia, Claudia Raja Espíndola, Otávio M. Bonaldo, Myrna C. Daniel-Ribeiro, Cláudio Tadeu Whitworth, Jimmy Smith, Chris Nielsen-Saines, Karin Pauvolid-Correa, Alex Siqueira, Marilda Agudo Mendonça Teixeira de Brasil, Patricia |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Penetra, Stephanie L. S. Silva, Michele F. B. da Resende, Paola Pina-Costa, Anielle Santos, Heloisa F. P. Guaraldo, Lusiele Calvet, Guilherme A. Ogrzewalska, Maria Arantes, Ighor Zukeram, Ketiuce Araújo, Mia F. de Lima, Ana Beatriz Machado Lopes, Renata Serrano Lira-Silva, Larissa R. Moraes, Isabella V. Wakimoto, Mayumi D. Fuller, Trevon L. Gabaglia, Claudia Raja Espíndola, Otávio M. Bonaldo, Myrna C. Daniel-Ribeiro, Cláudio Tadeu Whitworth, Jimmy Smith, Chris Nielsen-Saines, Karin Pauvolid-Correa, Alex Siqueira, Marilda Agudo Mendonça Teixeira de Brasil, Patricia |
dc.subject.en.pt_BR.fl_str_mv |
COVID-19 SARS-CoV-2 variants Health personnel Post-acute syndrome Reinfection Whole-genome sequencing |
topic |
COVID-19 SARS-CoV-2 variants Health personnel Post-acute syndrome Reinfection Whole-genome sequencing Breakthrough infection |
dc.subject.en.none.fl_str_mv |
Breakthrough infection |
description |
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-12-17T12:11:10Z |
dc.date.available.fl_str_mv |
2021-12-17T12:11:10Z |
dc.date.issued.fl_str_mv |
2021 |
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dc.identifier.citation.fl_str_mv |
PENETRA, Stephanie L. S. et al. Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil. International Journal of Infectious Diseases, v. 114, p. 58-61, 2021. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/50470 |
dc.identifier.issn.pt_BR.fl_str_mv |
1201-9712 |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.ijid.2021.10.048 |
identifier_str_mv |
PENETRA, Stephanie L. S. et al. Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil. International Journal of Infectious Diseases, v. 114, p. 58-61, 2021. 1201-9712 10.1016/j.ijid.2021.10.048 |
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Elsevier |
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