Neuroendocrine control of macrophage development and function

Detalhes bibliográficos
Autor(a) principal: Jurberg, Arnon Dias
Data de Publicação: 2018
Outros Autores: Almeida, Vinícius Cotta de, Temerozo, Jairo Ramos, Savino, Wilson, Bou-Habib, Dumith Chequer, Riederer, Ingo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/31523
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil.
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spelling Jurberg, Arnon DiasAlmeida, Vinícius Cotta deTemerozo, Jairo RamosSavino, WilsonBou-Habib, Dumith ChequerRiederer, Ingo2019-02-10T19:40:25Z2019-02-10T19:40:25Z2018JURBERG, Arnon Dias et al. Neuroendocrine Control of Macrophage Development and Function. Frontiers in Immunology, v. 9, p. 1-14, June 2018.1664-3224https://www.arca.fiocruz.br/handle/icict/3152310.3389/fimmu.2018.01440engFrontiers MediaMacrófagosMonócitosSistema neuroendócrinoHormôniosNeurotransmissoresEstresseGlucocorticóidesMacrophagesMonocytesNeuroendocrine systemHormonesNeurotransmittersStressGlucocorticoidsNeuroendocrine control of macrophage development and functioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil.Macrophages carry out numerous physiological activities that are essential for both systemic and local homeostasis, as well as innate and adaptive immune responses. Their biology is intricately regulated by hormones, neuropeptides, and neurotransmitters, establishing distinct neuroendocrine axes. The control is pleiotropic, including maturation of bone marrow-derived myeloid precursors, cell differentiation into functional subpopulations, cytotoxic activity, phagocytosis, production of inflammatory mediators, antigen presentation, and activation of effector lymphocytes. Additionally, neuroendocrine components modulate macrophage ability to influence tumor growth and to prevent the spreading of infective agents. Interestingly, macrophage-derived factors enhance glucocorticoid production through the stimulation of the hypothalamic–pituitary–adrenal axis. These bidirectional effects highlight a tightly controlled balance between neuroendocrine stimuli and macrophage function in the development of innate and adaptive immune responses. Herein, we discuss how components of neuroendocrine axes impact on macrophage development and function and may ultimately influence inflammation, tissue repair, infection, or cancer progression. The knowledge of the crosstalk between macrophages and endocrine or brain-derived components may contribute to improve and create new approaches with clinical relevance in homeostatic or pathological conditions.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/31523/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALarnondias_juberg_etal_IOC_2018.pdfarnondias_juberg_etal_IOC_2018.pdfapplication/pdf2042436https://www.arca.fiocruz.br/bitstream/icict/31523/2/arnondias_juberg_etal_IOC_2018.pdfe62a73d671b9925b43cab1a45f36a80aMD52TEXTarnondias_juberg_etal_IOC_2018.pdf.txtarnondias_juberg_etal_IOC_2018.pdf.txtExtracted texttext/plain89943https://www.arca.fiocruz.br/bitstream/icict/31523/3/arnondias_juberg_etal_IOC_2018.pdf.txtc69077ce901fd9f4fed1f19ef19c2102MD53icict/315232023-09-05 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dc.title.pt_BR.fl_str_mv Neuroendocrine control of macrophage development and function
title Neuroendocrine control of macrophage development and function
spellingShingle Neuroendocrine control of macrophage development and function
Jurberg, Arnon Dias
Macrófagos
Monócitos
Sistema neuroendócrino
Hormônios
Neurotransmissores
Estresse
Glucocorticóides
Macrophages
Monocytes
Neuroendocrine system
Hormones
Neurotransmitters
Stress
Glucocorticoids
title_short Neuroendocrine control of macrophage development and function
title_full Neuroendocrine control of macrophage development and function
title_fullStr Neuroendocrine control of macrophage development and function
title_full_unstemmed Neuroendocrine control of macrophage development and function
title_sort Neuroendocrine control of macrophage development and function
author Jurberg, Arnon Dias
author_facet Jurberg, Arnon Dias
Almeida, Vinícius Cotta de
Temerozo, Jairo Ramos
Savino, Wilson
Bou-Habib, Dumith Chequer
Riederer, Ingo
author_role author
author2 Almeida, Vinícius Cotta de
Temerozo, Jairo Ramos
Savino, Wilson
Bou-Habib, Dumith Chequer
Riederer, Ingo
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Jurberg, Arnon Dias
Almeida, Vinícius Cotta de
Temerozo, Jairo Ramos
Savino, Wilson
Bou-Habib, Dumith Chequer
Riederer, Ingo
dc.subject.other.pt_BR.fl_str_mv Macrófagos
Monócitos
Sistema neuroendócrino
Hormônios
Neurotransmissores
Estresse
Glucocorticóides
topic Macrófagos
Monócitos
Sistema neuroendócrino
Hormônios
Neurotransmissores
Estresse
Glucocorticóides
Macrophages
Monocytes
Neuroendocrine system
Hormones
Neurotransmitters
Stress
Glucocorticoids
dc.subject.en.pt_BR.fl_str_mv Macrophages
Monocytes
Neuroendocrine system
Hormones
Neurotransmitters
Stress
Glucocorticoids
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-02-10T19:40:25Z
dc.date.available.fl_str_mv 2019-02-10T19:40:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv JURBERG, Arnon Dias et al. Neuroendocrine Control of Macrophage Development and Function. Frontiers in Immunology, v. 9, p. 1-14, June 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31523
dc.identifier.issn.pt_BR.fl_str_mv 1664-3224
dc.identifier.doi.none.fl_str_mv 10.3389/fimmu.2018.01440
identifier_str_mv JURBERG, Arnon Dias et al. Neuroendocrine Control of Macrophage Development and Function. Frontiers in Immunology, v. 9, p. 1-14, June 2018.
1664-3224
10.3389/fimmu.2018.01440
url https://www.arca.fiocruz.br/handle/icict/31523
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/31523/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/31523/2/arnondias_juberg_etal_IOC_2018.pdf
https://www.arca.fiocruz.br/bitstream/icict/31523/3/arnondias_juberg_etal_IOC_2018.pdf.txt
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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