Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts.

Detalhes bibliográficos
Autor(a) principal: Santos, Luciano Cincurá Silva
Data de Publicação: 2007
Outros Autores: Ramos, Eduardo Antônio Gonçalves, Gurgel, Clarissa Araújo Silva, Santana, Edmar José Borges de, Santos, Jean Nunes dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/10243
Resumo: Universidade Federal da Bahia. Escola de Dentista. Salvador, BA, Brasil
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spelling Santos, Luciano Cincurá SilvaRamos, Eduardo Antônio GonçalvesGurgel, Clarissa Araújo SilvaSantana, Edmar José Borges deSantos, Jean Nunes dos2015-05-05T17:36:10Z2015-05-05T17:36:10Z2007SANTOS, L. C. et al. Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts. Journal of Molecular Histology, v. 38, n. 3, p. 201-205, 2007.1567-2379https://www.arca.fiocruz.br/handle/icict/1024310.1007/s10735-007-9088-3engSpringer VerlagImmunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal da Bahia. Escola de Dentista. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Histopatologia. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Histopatologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Escola de Dentista. Laboratorio de Patologia Oral. Salvador, BA, BrasilUniversidade Federal da Bahia. Escola de Dentista. Laboratorio de Patologia Oral. Salvador, BA, BrasilObjective Dental granulomas (DGs) and radicular cysts (RCs) are chronic periapical lesions frequently involving the jaws. Langerhans cells (LCs) are dendritic cells responsible for the presentation of antigens to T lymphocytes. This study examined the expression of LCs in DG and RCs by immunohistochemical staining. Study Design Eighteen cases of DGs and 26 cases of RCs were analyzed using anti-CD1a marker. Results CD1a-labeled LCs were observed in 11.1% of DGs and in 69.2% of RCs, showing a significant correlation (P < 0.0001; Fisher’s test). In DGs, LCs were only observed in granulation tissue, showing discrete immunostaining density. In RCs, LCs exhibited both a round and a dendritic shape in all epithelial layers. Although a correlation was observed between immunostaining density and epithelial thickness, as well as between immunostaining and inflammatory intensity, the differences were not significant in radicular cysts.Radicular cystDental granulomaImmunohistochemistryLangerhans cellCélulas de Langerhans/imunologiaGranuloma Periapical/imunologiaCisto Radicular/imunologiaAdolescenteAdultoIdosoAntígenos CD1/imunologiaCriançaPré-EscolarFemeninoHumanosImuno-HistoquímicaMasculinoMeia-IdadeGranuloma Periapical/patologiaCisto Radicular/patologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82352https://www.arca.fiocruz.br/bitstream/icict/10243/1/license.txtafbdf7d7a9bcf771a1cc7edf5f618413MD51ORIGINALSantos L C S Immunohistochemical....pdfSantos L C S Immunohistochemical....pdfapplication/pdf204472https://www.arca.fiocruz.br/bitstream/icict/10243/2/Santos%20L%20C%20S%20Immunohistochemical....pdfbc1085732a4c93ef84c30a0422b941c0MD52TEXTSantos L C S Immunohistochemical....pdf.txtSantos L C S Immunohistochemical....pdf.txtExtracted texttext/plain20879https://www.arca.fiocruz.br/bitstream/icict/10243/3/Santos%20L%20C%20S%20Immunohistochemical....pdf.txtf9605c1cddc505353f7d5ae003e0b14aMD53icict/102432023-03-15 14:33:08.665oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:08Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts.
title Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts.
spellingShingle Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts.
Santos, Luciano Cincurá Silva
Radicular cyst
Dental granuloma
Immunohistochemistry
Langerhans cell
Células de Langerhans/imunologia
Granuloma Periapical/imunologia
Cisto Radicular/imunologia
Adolescente
Adulto
Idoso
Antígenos CD1/imunologia
Criança
Pré-Escolar
Femenino
Humanos
Imuno-Histoquímica
Masculino
Meia-Idade
Granuloma Periapical/patologia
Cisto Radicular/patologia
title_short Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts.
title_full Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts.
title_fullStr Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts.
title_full_unstemmed Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts.
title_sort Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts.
author Santos, Luciano Cincurá Silva
author_facet Santos, Luciano Cincurá Silva
Ramos, Eduardo Antônio Gonçalves
Gurgel, Clarissa Araújo Silva
Santana, Edmar José Borges de
Santos, Jean Nunes dos
author_role author
author2 Ramos, Eduardo Antônio Gonçalves
Gurgel, Clarissa Araújo Silva
Santana, Edmar José Borges de
Santos, Jean Nunes dos
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santos, Luciano Cincurá Silva
Ramos, Eduardo Antônio Gonçalves
Gurgel, Clarissa Araújo Silva
Santana, Edmar José Borges de
Santos, Jean Nunes dos
dc.subject.en.pt_BR.fl_str_mv Radicular cyst
Dental granuloma
Immunohistochemistry
Langerhans cell
topic Radicular cyst
Dental granuloma
Immunohistochemistry
Langerhans cell
Células de Langerhans/imunologia
Granuloma Periapical/imunologia
Cisto Radicular/imunologia
Adolescente
Adulto
Idoso
Antígenos CD1/imunologia
Criança
Pré-Escolar
Femenino
Humanos
Imuno-Histoquímica
Masculino
Meia-Idade
Granuloma Periapical/patologia
Cisto Radicular/patologia
dc.subject.decs.pt_BR.fl_str_mv Células de Langerhans/imunologia
Granuloma Periapical/imunologia
Cisto Radicular/imunologia
Adolescente
Adulto
Idoso
Antígenos CD1/imunologia
Criança
Pré-Escolar
Femenino
Humanos
Imuno-Histoquímica
Masculino
Meia-Idade
Granuloma Periapical/patologia
Cisto Radicular/patologia
description Universidade Federal da Bahia. Escola de Dentista. Salvador, BA, Brasil
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2015-05-05T17:36:10Z
dc.date.available.fl_str_mv 2015-05-05T17:36:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SANTOS, L. C. et al. Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts. Journal of Molecular Histology, v. 38, n. 3, p. 201-205, 2007.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/10243
dc.identifier.issn.none.fl_str_mv 1567-2379
dc.identifier.doi.none.fl_str_mv 10.1007/s10735-007-9088-3
identifier_str_mv SANTOS, L. C. et al. Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts. Journal of Molecular Histology, v. 38, n. 3, p. 201-205, 2007.
1567-2379
10.1007/s10735-007-9088-3
url https://www.arca.fiocruz.br/handle/icict/10243
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Verlag
publisher.none.fl_str_mv Springer Verlag
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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