Novel epicardial off-pump device for mitral regurgitation: acute evaluation

Detalhes bibliográficos
Autor(a) principal: Takaseya, Tohru
Data de Publicação: 2010
Outros Autores: Shiose, Akira, Saraiva, Roberto M., Fumoto, Hideyuki, Arakawa, Yoko, Juravic, Mark, Lombardi, Pierluca, Fukamachi, Kiyotaka
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/37458
Resumo: Roberto M. Saraiva. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
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spelling Takaseya, TohruShiose, AkiraSaraiva, Roberto M.Fumoto, HideyukiArakawa, YokoJuravic, MarkLombardi, PierlucaFukamachi, Kiyotaka2019-11-28T14:33:01Z2019-11-28T14:33:01Z2010TAKASEYA, Tohru et al. Novel epicardial off-pump device for mitral regurgitation: acute evaluation. European Journal of Cardio-Thoracic Surgery, v. 37, p. 1291-1296, 2010.1010-7940https://www.arca.fiocruz.br/handle/icict/3745810.1016/j.ejcts.2009.11.0541873-734XRoberto M. Saraiva. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.2020-11-28Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Department of Cardiovascular Medicine, Heart & Vascular Institute. Cleveland, OH, USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.MAQUET Cardiovascular LLC. San Jose, CA, USA.MAQUET Cardiovascular LLC. San Jose, CA, USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Objective: This study evaluates the ability of a novel epicardial annuloplasty device Mitral Touch (MAQUET Cardiovascular LLC, San Jose, CA, USA) to reduce functional mitral regurgitation (MR) in a rapid ventricular pacing-induced dilated cardiomyopathy model in dogs. Methods: A median sternotomy was performed in 13 dogs after MR induction by rapid ventricular pacing (230 beats/min for an average of 35.6 +/- 12.8 days). Two-dimensional epicardial echocardiographic and haemodynamic measurements were performed to evaluate the baseline MR grade, the septal—lateral (S—L) dimension of the mitral annulus, mitral valve (MV) geometry and left ventricular function. The Mitral Touch was implanted by sliding the anterior arm onto the floor of the transverse sinus and positioning the posterior arm just apical to the atrioventricular groove on the left ventricular posterolateral wall. The 24-mm-long device was implanted in eight dogs, the 27-mm-long device in four and the 30-mm standard length device in one. MR grade, S—L dimension and haemodynamics data acquisition were immediately rechecked after device implantation. Results: All implantations, which took only approximately 30 s to deploy, were performed on beating hearts without cardiopulmonary bypass. In one early case, after extended manipulation with undersized devices, an atrial laceration was created and bleeding occurred. Design changes were made to eliminate this complication. The MR grade was significantly (p = 0.003) reduced from 3.1 +/- 1.1 at baseline to 1.4+/- 0.8 after device implantation. The S—L dimension at end of systole was also significantly ( p = 0.001) reduced from 2.7 0.4 cm at baseline to 2.3 +/- 0.3 cm after device implantation (% reduction: 15.1+/- 10.6%). The mitral valve coaptation length was significantly (p = 0.0001) increased from 0.36+/- 0.11 cm to 0.50 0.08 cm, and the mitral valve tethering area was significantly (p = 0.0003) decreased from 1.36+/- 0.38 cm2 to 0.81+/- 0.29 cm2 after mitral touch implantation. Conclusions: This new epicardial device was effective in significantly reducing MR and S—L dimensions acutely on the beating heart without requiring the use of cardiopulmonary bypass. Further studies are necessary to confirm the long-term maintenance of MR and S—L reductions.engOxford University PressNovel epicardial off-pump device for mitral regurgitation: acute evaluationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleMitral valve repairMinimally invasive surgeryOff-pump surgeryinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/37458/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Takaseya_Tohru_etal_INI_2010.pdfve_Takaseya_Tohru_etal_INI_2010.pdfapplication/pdf238739https://www.arca.fiocruz.br/bitstream/icict/37458/2/ve_Takaseya_Tohru_etal_INI_2010.pdf66ed3e0db5942906a8774566b180b726MD52TEXTve_Takaseya_Tohru_etal_INI_2010.pdf.txtve_Takaseya_Tohru_etal_INI_2010.pdf.txtExtracted texttext/plain29467https://www.arca.fiocruz.br/bitstream/icict/37458/3/ve_Takaseya_Tohru_etal_INI_2010.pdf.txt0a348fa421ab112fa5793d57243690a5MD53icict/374582021-03-24 16:32:39.879oai:www.arca.fiocruz.br:icict/37458Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:39Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Novel epicardial off-pump device for mitral regurgitation: acute evaluation
title Novel epicardial off-pump device for mitral regurgitation: acute evaluation
spellingShingle Novel epicardial off-pump device for mitral regurgitation: acute evaluation
Takaseya, Tohru
Mitral valve repair
Minimally invasive surgery
Off-pump surgery
title_short Novel epicardial off-pump device for mitral regurgitation: acute evaluation
title_full Novel epicardial off-pump device for mitral regurgitation: acute evaluation
title_fullStr Novel epicardial off-pump device for mitral regurgitation: acute evaluation
title_full_unstemmed Novel epicardial off-pump device for mitral regurgitation: acute evaluation
title_sort Novel epicardial off-pump device for mitral regurgitation: acute evaluation
author Takaseya, Tohru
author_facet Takaseya, Tohru
Shiose, Akira
Saraiva, Roberto M.
Fumoto, Hideyuki
Arakawa, Yoko
Juravic, Mark
Lombardi, Pierluca
Fukamachi, Kiyotaka
author_role author
author2 Shiose, Akira
Saraiva, Roberto M.
Fumoto, Hideyuki
Arakawa, Yoko
Juravic, Mark
Lombardi, Pierluca
Fukamachi, Kiyotaka
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Takaseya, Tohru
Shiose, Akira
Saraiva, Roberto M.
Fumoto, Hideyuki
Arakawa, Yoko
Juravic, Mark
Lombardi, Pierluca
Fukamachi, Kiyotaka
dc.subject.en.pt_BR.fl_str_mv Mitral valve repair
Minimally invasive surgery
Off-pump surgery
topic Mitral valve repair
Minimally invasive surgery
Off-pump surgery
description Roberto M. Saraiva. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2019-11-28T14:33:01Z
dc.date.available.fl_str_mv 2019-11-28T14:33:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TAKASEYA, Tohru et al. Novel epicardial off-pump device for mitral regurgitation: acute evaluation. European Journal of Cardio-Thoracic Surgery, v. 37, p. 1291-1296, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/37458
dc.identifier.issn.pt_BR.fl_str_mv 1010-7940
dc.identifier.doi.none.fl_str_mv 10.1016/j.ejcts.2009.11.054
dc.identifier.eissn.none.fl_str_mv 1873-734X
identifier_str_mv TAKASEYA, Tohru et al. Novel epicardial off-pump device for mitral regurgitation: acute evaluation. European Journal of Cardio-Thoracic Surgery, v. 37, p. 1291-1296, 2010.
1010-7940
10.1016/j.ejcts.2009.11.054
1873-734X
url https://www.arca.fiocruz.br/handle/icict/37458
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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