Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model

Detalhes bibliográficos
Autor(a) principal: Takaseya, Tohru
Data de Publicação: 2010
Outros Autores: Fumoto, Hideyuki, Saraiva, Roberto M., Shiose, Akira, Arakawa, Yoko, Park, Margaret, Rao, Santosh, Dessoffy, Raymond, Kramer, Larry D., Juravic, Mark, Lombardi, Pierluca, Fukamachi, Kiyotaka
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/37508
Resumo: Roberto M. Saraiva. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
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spelling Takaseya, TohruFumoto, HideyukiSaraiva, Roberto M.Shiose, AkiraArakawa, YokoPark, MargaretRao, SantoshDessoffy, RaymondKramer, Larry D.Juravic, MarkLombardi, PierlucaFukamachi, Kiyotaka2019-11-29T14:04:24Z2019-11-29T14:04:24Z2010TAKASEYA, Tohru et al. Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model. Innovations, v. 5, n. 1, p. 28-32, Jan./Feb. 2010.1556-9845https://www.arca.fiocruz.br/handle/icict/3750810.1097/imi.0b013e3181cdf7351559-0879Roberto M. Saraiva. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.2020-11-29Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Heart and Vascular Institute. Department of Cardiovascular Medicine. Cleveland, OH, USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Heart and Vascular Institute. Department of Cardiovascular Medicine. Cleveland, OH, USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.MAQUET Cardiovascular LLC. San Jose, CA USA.MAQUET Cardiovascular LLC. San Jose, CA USA.Cleveland Clinic. Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Objective: The purpose of this study was to evaluate the implantability of a novel epicardial mitral annuloplasty device and its ability to reduce the septal-lateral (S-L) dimension of the mitral annulus. Methods: The devices were implanted on the beating heart in 2 healthy dogs (the 24-mm long device in dog A and the 27-mm and 24-mm standard devices in dog B) by sliding the anterior arm onto the floor of the transverse sinus and positioning the posterior arm just apical to the atrioventricular groove on the left ventricular posterolateral wall. The devices were secured with titanium helical tacks driven through the device into the ventricular wall. Twodimensional epicardial echocardiograms were performed before and after device implantation to evaluate the degree of mitral regurgitation (MR) and the S-L dimension. Results: Device implantation was uneventful, taking only ~30 seconds to deploy. MR (1) in both dogs at baseline was reduced to zero after implant. The reductions in S-L dimension in systole for the 24-mm device were 7.5% in dog A and 30.5% in dog B. For the 27-mm device in dog B, S-L reduction in systole was 29.9%. The leaflet coaptation length was increased in both cases. Conclusions: The new device was effective in reducing S-L dimension and 1 MR without requiring the use of cardiopulmonary bypass. We are currently evaluating this device for the treatment of MR in a rapid-pacing canine heart failure model.engLippincott, Williams & WilkinsAcute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine modelinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleMitral valve repairMinimally invasive surgeryOff-pump surgeryinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/37508/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Takaseya_Tohru_etal_INI_2010.pdfve_Takaseya_Tohru_etal_INI_2010.pdfapplication/pdf905226https://www.arca.fiocruz.br/bitstream/icict/37508/2/ve_Takaseya_Tohru_etal_INI_2010.pdf05ca0ece501b7bd6d54e60f8580ae922MD52TEXTve_Takaseya_Tohru_etal_INI_2010.pdf.txtve_Takaseya_Tohru_etal_INI_2010.pdf.txtExtracted texttext/plain21414https://www.arca.fiocruz.br/bitstream/icict/37508/3/ve_Takaseya_Tohru_etal_INI_2010.pdf.txt679593b4d9a37cf65b19962ce31c26c4MD53icict/375082021-03-24 16:32:40.214oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:40Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model
title Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model
spellingShingle Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model
Takaseya, Tohru
Mitral valve repair
Minimally invasive surgery
Off-pump surgery
title_short Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model
title_full Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model
title_fullStr Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model
title_full_unstemmed Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model
title_sort Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model
author Takaseya, Tohru
author_facet Takaseya, Tohru
Fumoto, Hideyuki
Saraiva, Roberto M.
Shiose, Akira
Arakawa, Yoko
Park, Margaret
Rao, Santosh
Dessoffy, Raymond
Kramer, Larry D.
Juravic, Mark
Lombardi, Pierluca
Fukamachi, Kiyotaka
author_role author
author2 Fumoto, Hideyuki
Saraiva, Roberto M.
Shiose, Akira
Arakawa, Yoko
Park, Margaret
Rao, Santosh
Dessoffy, Raymond
Kramer, Larry D.
Juravic, Mark
Lombardi, Pierluca
Fukamachi, Kiyotaka
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Takaseya, Tohru
Fumoto, Hideyuki
Saraiva, Roberto M.
Shiose, Akira
Arakawa, Yoko
Park, Margaret
Rao, Santosh
Dessoffy, Raymond
Kramer, Larry D.
Juravic, Mark
Lombardi, Pierluca
Fukamachi, Kiyotaka
dc.subject.en.pt_BR.fl_str_mv Mitral valve repair
Minimally invasive surgery
Off-pump surgery
topic Mitral valve repair
Minimally invasive surgery
Off-pump surgery
description Roberto M. Saraiva. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2019-11-29T14:04:24Z
dc.date.available.fl_str_mv 2019-11-29T14:04:24Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TAKASEYA, Tohru et al. Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model. Innovations, v. 5, n. 1, p. 28-32, Jan./Feb. 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/37508
dc.identifier.issn.pt_BR.fl_str_mv 1556-9845
dc.identifier.doi.none.fl_str_mv 10.1097/imi.0b013e3181cdf735
dc.identifier.eissn.none.fl_str_mv 1559-0879
identifier_str_mv TAKASEYA, Tohru et al. Acute feasibility study of a novel device for the treatment of mitral regurgitation in a normal canine model. Innovations, v. 5, n. 1, p. 28-32, Jan./Feb. 2010.
1556-9845
10.1097/imi.0b013e3181cdf735
1559-0879
url https://www.arca.fiocruz.br/handle/icict/37508
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Lippincott, Williams & Wilkins
publisher.none.fl_str_mv Lippincott, Williams & Wilkins
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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institution FIOCRUZ
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