SARS-CoV-2: Should We Be Concerned about the Nervous System?

Detalhes bibliográficos
Autor(a) principal: Silva, Marcus Tulius T.
Data de Publicação: 2020
Outros Autores: Lima, Marco, Araujo, Abelardo Q.-C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/43560
Resumo: Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Complexo Hospitalar de Niterói. Niterói, RJ, Brasil.
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spelling Silva, Marcus Tulius T.Lima, MarcoAraujo, Abelardo Q.-C.2020-09-22T21:00:54Z2020-09-22T21:00:54Z2020SILVA, Marcus Tulius T. et al. SARS-CoV-2: Should We Be Concerned about the Nervous System? The American Journal of Tropical Medicine and Hygiene, v. 103, n. 3, p. 993-998, 2020.1476-1645https://www.arca.fiocruz.br/handle/icict/4356010.4269/ajtmh.20-0447engASTMHSARS-CoV-2: Should We Be Concerned about the Nervous System?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Complexo Hospitalar de Niterói. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Rio de Janeiro, RJ, Brasil.The COVID-19 pandemic has proved to be an enormous challenge to the health of the world population with tremendous consequences for the world economy. New knowledge about COVID-19 is being acquired continuously. Although the main manifestation of COVID-19 is SARS, dysfunction in other organs has been described in the last months. Neurological aspects of COVID-19 are still an underreported subject. However, a plethora of previous studies has shown that human CoVs might be neurotropic, neuroinvasive, and neurovirulent, highlighting the importance of this knowledge by physicians. Besides, several neurological manifestations had been described as complications of two other previous outbreaks of CoV diseases (SARS ad Middle East respiratory syndrome). Therefore, we should be watchful, searching for early evidence of neurological insults and promoting clinical protocols to investigate them. Our objectives are to review the potential neuropathogenesis of this new CoV and the neurological profile of COVID-19 patients described so far.COVID-19Coronavirus InfectionsNervous System DiseasesSevere acute respiratory syndrome coronavirus 2SARS-CoV-2info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83132https://www.arca.fiocruz.br/bitstream/icict/43560/1/license.txt70425d8cb6e40fdcf4edd2ef0660b45bMD51ORIGINALtpmd200447.pdftpmd200447.pdfapplication/pdf101100https://www.arca.fiocruz.br/bitstream/icict/43560/2/tpmd200447.pdfe7d762b2c6262ed393ada3ef8c5ff6a0MD52TEXTtpmd200447.pdf.txttpmd200447.pdf.txtExtracted texttext/plain38461https://www.arca.fiocruz.br/bitstream/icict/43560/3/tpmd200447.pdf.txtfb9c0eecd89d772e12b489d10bcd2fbfMD53icict/435602020-09-23 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dc.title.pt_BR.fl_str_mv SARS-CoV-2: Should We Be Concerned about the Nervous System?
title SARS-CoV-2: Should We Be Concerned about the Nervous System?
spellingShingle SARS-CoV-2: Should We Be Concerned about the Nervous System?
Silva, Marcus Tulius T.
COVID-19
Coronavirus Infections
Nervous System Diseases
Severe acute respiratory syndrome coronavirus 2
SARS-CoV-2
title_short SARS-CoV-2: Should We Be Concerned about the Nervous System?
title_full SARS-CoV-2: Should We Be Concerned about the Nervous System?
title_fullStr SARS-CoV-2: Should We Be Concerned about the Nervous System?
title_full_unstemmed SARS-CoV-2: Should We Be Concerned about the Nervous System?
title_sort SARS-CoV-2: Should We Be Concerned about the Nervous System?
author Silva, Marcus Tulius T.
author_facet Silva, Marcus Tulius T.
Lima, Marco
Araujo, Abelardo Q.-C.
author_role author
author2 Lima, Marco
Araujo, Abelardo Q.-C.
author2_role author
author
dc.contributor.author.fl_str_mv Silva, Marcus Tulius T.
Lima, Marco
Araujo, Abelardo Q.-C.
dc.subject.en.pt_BR.fl_str_mv COVID-19
Coronavirus Infections
Nervous System Diseases
Severe acute respiratory syndrome coronavirus 2
SARS-CoV-2
topic COVID-19
Coronavirus Infections
Nervous System Diseases
Severe acute respiratory syndrome coronavirus 2
SARS-CoV-2
description Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Complexo Hospitalar de Niterói. Niterói, RJ, Brasil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-09-22T21:00:54Z
dc.date.available.fl_str_mv 2020-09-22T21:00:54Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, Marcus Tulius T. et al. SARS-CoV-2: Should We Be Concerned about the Nervous System? The American Journal of Tropical Medicine and Hygiene, v. 103, n. 3, p. 993-998, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43560
dc.identifier.issn.pt_BR.fl_str_mv 1476-1645
dc.identifier.doi.none.fl_str_mv 10.4269/ajtmh.20-0447
identifier_str_mv SILVA, Marcus Tulius T. et al. SARS-CoV-2: Should We Be Concerned about the Nervous System? The American Journal of Tropical Medicine and Hygiene, v. 103, n. 3, p. 993-998, 2020.
1476-1645
10.4269/ajtmh.20-0447
url https://www.arca.fiocruz.br/handle/icict/43560
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv ASTMH
publisher.none.fl_str_mv ASTMH
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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