Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/47610 |
Resumo: | INOVA Fiocruz, Serrapilheira Institute, and D’Or Institute for Research and Education. M.G. is supported by Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro. |
id |
CRUZ_50a81a88dd92ef086978abc352009151 |
---|---|
oai_identifier_str |
oai:www.arca.fiocruz.br:icict/47610 |
network_acronym_str |
CRUZ |
network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
repository_id_str |
2135 |
spelling |
Nonaka, Carolina Kymie VasquesFranco, Marília MirandaGräf, TiagoBarcia, Camila Araújo de LorenzoMendonça, Renata Naves de ÁvilaSousa, Karoline Almeida Felix deNeiva, Leila Machado CostaFosenca, VagnerMendes, Ana Verena AlmeidaAguiar, Renato Santana deGiovanetti, MartaSouza, Bruno Solano de Freitas2021-06-10T13:11:00Z2021-06-10T13:11:00Z2021NONAKA, Carolina Kymie Vasques et al. Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil. Emerging Infectious Diseases, v. 27, n. 5, May 2021.1080-6040https://www.arca.fiocruz.br/handle/icict/4761010.3201/eid2705.210191INOVA Fiocruz, Serrapilheira Institute, and D’Or Institute for Research and Education. M.G. is supported by Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro.Instituto D'Or de Ensino e Pesquisa. Salvador, BA, Brasil / Hospital São Rafael. Centro de Biotecnologia e Terapia Celular. Salvador, BA, Brasil.Hospital São Rafael. Departamento de Infectologia. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Hospital São Rafael. Departamento de Infectologia. Salvador, BA, Brasil.Hospital São Rafael. Departamento de Infectologia. Salvador, BA, Brasil.Hospital São Rafael. Departamento de Infectologia. Salvador, BA, Brasil.São Rafael Hospital. Department of Infectology. Salvador, BA, Brazil.Ministério da Saúde. Coordenação Geral dos Laboratórios de Saúde Pública. Brasília, DF, Brasil / University of KwaZulu-Natal. College of Health Sciences. Durban, South Africa / Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil.Hospital São Rafael. Departamento de Infectologia. Salvador, BA, Brasil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / University Campus Bio-Medico of Rome. Unit of Medical Statistics and Molecular Epidemiology. Rome, Italy.Instituto D'Or de Ensino e Pesquisa. Salvador, BA, Brasil / Hospital São Rafael. Centro de Biotecnologia e Terapia Celular. Salvador, BA, Brasil.Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection in recovered patients has been reported. We describe a case of reinfection from distinct virus lineages in Brazil harboring the E484K mutation, a variant associated with escape from neutralizing antibodies.engCenters for Disease Control and PreventionCoronavirusSíndrome Respiratória Aguda GraveMutaçãoSars-CoV-2CoronavirusSevere Acute Respiratory SyndromeMutationSARS-Cov-2Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/47610/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALNonaka, Carolina Kymie Vasques Genomic....pdfNonaka, Carolina Kymie Vasques Genomic....pdfapplication/pdf1354161https://www.arca.fiocruz.br/bitstream/icict/47610/2/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Genomic....pdf44ecb72ccdaabbdcced0d2a7b316aab2MD52TEXTNonaka, Carolina Kymie Vasques Genomic....pdf.txtNonaka, Carolina Kymie Vasques Genomic....pdf.txtExtracted texttext/plain12712https://www.arca.fiocruz.br/bitstream/icict/47610/3/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Genomic....pdf.txt66efb0cb8f83e0f5be1fd9799896c5a8MD53icict/476102023-09-04 10:53:59.003oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-04T13:53:59Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.en.fl_str_mv |
Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil |
title |
Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil |
spellingShingle |
Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil Nonaka, Carolina Kymie Vasques Coronavirus Síndrome Respiratória Aguda Grave Mutação Sars-CoV-2 Coronavirus Severe Acute Respiratory Syndrome Mutation SARS-Cov-2 |
title_short |
Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil |
title_full |
Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil |
title_fullStr |
Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil |
title_full_unstemmed |
Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil |
title_sort |
Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil |
author |
Nonaka, Carolina Kymie Vasques |
author_facet |
Nonaka, Carolina Kymie Vasques Franco, Marília Miranda Gräf, Tiago Barcia, Camila Araújo de Lorenzo Mendonça, Renata Naves de Ávila Sousa, Karoline Almeida Felix de Neiva, Leila Machado Costa Fosenca, Vagner Mendes, Ana Verena Almeida Aguiar, Renato Santana de Giovanetti, Marta Souza, Bruno Solano de Freitas |
author_role |
author |
author2 |
Franco, Marília Miranda Gräf, Tiago Barcia, Camila Araújo de Lorenzo Mendonça, Renata Naves de Ávila Sousa, Karoline Almeida Felix de Neiva, Leila Machado Costa Fosenca, Vagner Mendes, Ana Verena Almeida Aguiar, Renato Santana de Giovanetti, Marta Souza, Bruno Solano de Freitas |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Nonaka, Carolina Kymie Vasques Franco, Marília Miranda Gräf, Tiago Barcia, Camila Araújo de Lorenzo Mendonça, Renata Naves de Ávila Sousa, Karoline Almeida Felix de Neiva, Leila Machado Costa Fosenca, Vagner Mendes, Ana Verena Almeida Aguiar, Renato Santana de Giovanetti, Marta Souza, Bruno Solano de Freitas |
dc.subject.other.pt_BR.fl_str_mv |
Coronavirus Síndrome Respiratória Aguda Grave Mutação Sars-CoV-2 |
topic |
Coronavirus Síndrome Respiratória Aguda Grave Mutação Sars-CoV-2 Coronavirus Severe Acute Respiratory Syndrome Mutation SARS-Cov-2 |
dc.subject.en.en.fl_str_mv |
Coronavirus Severe Acute Respiratory Syndrome Mutation SARS-Cov-2 |
description |
INOVA Fiocruz, Serrapilheira Institute, and D’Or Institute for Research and Education. M.G. is supported by Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-06-10T13:11:00Z |
dc.date.available.fl_str_mv |
2021-06-10T13:11:00Z |
dc.date.issued.fl_str_mv |
2021 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
NONAKA, Carolina Kymie Vasques et al. Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil. Emerging Infectious Diseases, v. 27, n. 5, May 2021. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/47610 |
dc.identifier.issn.pt_BR.fl_str_mv |
1080-6040 |
dc.identifier.doi.pt_BR.fl_str_mv |
10.3201/eid2705.210191 |
identifier_str_mv |
NONAKA, Carolina Kymie Vasques et al. Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil. Emerging Infectious Diseases, v. 27, n. 5, May 2021. 1080-6040 10.3201/eid2705.210191 |
url |
https://www.arca.fiocruz.br/handle/icict/47610 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Centers for Disease Control and Prevention |
publisher.none.fl_str_mv |
Centers for Disease Control and Prevention |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
collection |
Repositório Institucional da FIOCRUZ (ARCA) |
bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/47610/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/47610/2/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Genomic....pdf https://www.arca.fiocruz.br/bitstream/icict/47610/3/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Genomic....pdf.txt |
bitstream.checksum.fl_str_mv |
36b51ef91c52b5338d9d29ba0cc807bc 44ecb72ccdaabbdcced0d2a7b316aab2 66efb0cb8f83e0f5be1fd9799896c5a8 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
_version_ |
1813008989340827648 |