Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator

Detalhes bibliográficos
Autor(a) principal: Wanderley, Joao Luiz Mendes
Data de Publicação: 2012
Outros Autores: Costa, Jaqueline França, Borges, Valéria Matos, Barcinski, Marcello
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/15915
Resumo: Universidade Federal do Rio de Janeiro. Polo Universitário Macaé. Rio de Janeiro, RJ, Brasil.
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spelling Wanderley, Joao Luiz MendesCosta, Jaqueline FrançaBorges, Valéria MatosBarcinski, Marcello2016-09-22T16:24:09Z2016-09-22T16:24:09Z2012WANDERLEY, João Luiz Mendes; et al. Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator. Journal of Parasitology Research, v.2012, Article ID 981686, 7p, 2012.2090-0023https://www.arca.fiocruz.br/handle/icict/1591510.1155/2012/9816862090-0031engHindawi Publishing CorporationLeishmaniose cutâneaImunidadeParasitosExposição à fosfatidilserinaLeishmania amazonensisParasitesImunitePhosphatidylserinecutaneous leishmaniasisSubversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulatorinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro. Polo Universitário Macaé. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia de Investigação em Imunologia. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil.Leishmania amazonensis parasites cause progressive disease in most inbred mouse strains and are associated with the development of diffuse cutaneous leishmaniasis in humans. The poor activation of an effective cellular response is correlated with the ability of these parasites to infect mononuclear phagocytic cells without triggering their activation or actively suppressing innate responses of these cells. Here we discuss the possible role of phosphatidylserine exposure by these parasites as a main regulator of the mechanism underlying subversion of the immune system at different steps during the infection.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/15915/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALmarcelo_barcisnki_etal_IOC_2012.pdfmarcelo_barcisnki_etal_IOC_2012.pdfapplication/pdf698921https://www.arca.fiocruz.br/bitstream/icict/15915/2/marcelo_barcisnki_etal_IOC_2012.pdfac7e025987de0d146a1330324e609e1dMD52TEXTmarcelo_barcisnki_etal_IOC_2012.pdf.txtmarcelo_barcisnki_etal_IOC_2012.pdf.txtExtracted texttext/plain42395https://www.arca.fiocruz.br/bitstream/icict/15915/3/marcelo_barcisnki_etal_IOC_2012.pdf.txt1f3e7175e4bbb24b5dcaab45a8aecfdfMD53icict/159152023-09-14 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dc.title.pt_BR.fl_str_mv Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator
title Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator
spellingShingle Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator
Wanderley, Joao Luiz Mendes
Leishmaniose cutânea
Imunidade
Parasitos
Exposição à fosfatidilserina
Leishmania amazonensis
Parasites
Imunite
Phosphatidylserine
cutaneous leishmaniasis
title_short Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator
title_full Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator
title_fullStr Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator
title_full_unstemmed Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator
title_sort Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator
author Wanderley, Joao Luiz Mendes
author_facet Wanderley, Joao Luiz Mendes
Costa, Jaqueline França
Borges, Valéria Matos
Barcinski, Marcello
author_role author
author2 Costa, Jaqueline França
Borges, Valéria Matos
Barcinski, Marcello
author2_role author
author
author
dc.contributor.author.fl_str_mv Wanderley, Joao Luiz Mendes
Costa, Jaqueline França
Borges, Valéria Matos
Barcinski, Marcello
dc.subject.other.pt_BR.fl_str_mv Leishmaniose cutânea
Imunidade
Parasitos
Exposição à fosfatidilserina
topic Leishmaniose cutânea
Imunidade
Parasitos
Exposição à fosfatidilserina
Leishmania amazonensis
Parasites
Imunite
Phosphatidylserine
cutaneous leishmaniasis
dc.subject.en.pt_BR.fl_str_mv Leishmania amazonensis
Parasites
Imunite
Phosphatidylserine
cutaneous leishmaniasis
description Universidade Federal do Rio de Janeiro. Polo Universitário Macaé. Rio de Janeiro, RJ, Brasil.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2016-09-22T16:24:09Z
dc.date.available.fl_str_mv 2016-09-22T16:24:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv WANDERLEY, João Luiz Mendes; et al. Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator. Journal of Parasitology Research, v.2012, Article ID 981686, 7p, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/15915
dc.identifier.issn.pt_BR.fl_str_mv 2090-0023
dc.identifier.doi.none.fl_str_mv 10.1155/2012/981686
dc.identifier.eissn.none.fl_str_mv 2090-0031
identifier_str_mv WANDERLEY, João Luiz Mendes; et al. Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator. Journal of Parasitology Research, v.2012, Article ID 981686, 7p, 2012.
2090-0023
10.1155/2012/981686
2090-0031
url https://www.arca.fiocruz.br/handle/icict/15915
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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