The fungal cell wall: candida, cryptococcus, and aspergillus species

Detalhes bibliográficos
Autor(a) principal: Garcia-Rubio, Rocio
Data de Publicação: 2020
Outros Autores: Oliveira, Haroldo Cesar de, Rivera, Johanna, Trevijano-Contador, Nuria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/44810
Resumo: Link para o artigo publicado: https://www.frontiersin.org/articles/10.3389/fmicb.2019.02993/full
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spelling Garcia-Rubio, RocioOliveira, Haroldo Cesar deRivera, JohannaTrevijano-Contador, Nuria2020-12-11T15:02:20Z2020-12-11T15:02:20Z2020GARCIA-RUBIO, Rocio et al. The fungal cell wall: candida, cryptococcus, and aspergillus species. Frontiers Microbiology, v. 10, n. 2993, p. 1-13, 9 Jan. 2020.1664-302Xhttps://www.arca.fiocruz.br/handle/icict/4481010.3389/fmicb.2019.029931664-302XLink para o artigo publicado: https://www.frontiersin.org/articles/10.3389/fmicb.2019.02993/fullHackensack Meridian Health. Center for Discovery and Innovation. Nutley, NJ, USA.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Albert Einstein College of Medicine. Department of Medicine. Division of Infectious Diseases. New York, NY, USA.Albert Einstein College of Medicine. Department of Medicine. Division of Infectious Diseases. New York, NY, USA.The fungal cell wall is located outside the plasma membrane and is the cell compartment that mediates all the relationships of the cell with the environment. It protects the contents of the cell, gives rigidity and defines the cellular structure. The cell wall is a skeleton with high plasticity that protects the cell from different stresses, among which osmotic changes stand out. The cell wall allows interaction with the external environment since some of its proteins are adhesins and receptors. Since, some components have a high immunogenic capacity, certain wall components can drive the host’s immune response to promote fungus growth and dissemination. The cell wall is a characteristic structure of fungi and is composed mainly of glucans, chitin and glycoproteins. As the components of the fungal cell wall are not present in humans, this structure is an excellent target for antifungal therapy. In this article, we review recent data on the composition and synthesis, influence of the components of the cell wall in fungi-host interaction and the role as a target for the next generation of antifungal drugs in yeasts (Candida and Cryptococcus) and filamentous fungi (Aspergillus).engFrontiers MediaThe fungal cell wall: candida, cryptococcus, and aspergillus speciesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCell wallCandidaCryptococcusAspergillusSynthesisCompositioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.eng.fl_str_mv The fungal cell wall: candida, cryptococcus, and aspergillus species
title The fungal cell wall: candida, cryptococcus, and aspergillus species
spellingShingle The fungal cell wall: candida, cryptococcus, and aspergillus species
Garcia-Rubio, Rocio
Cell wall
Candida
Cryptococcus
Aspergillus
Synthesis
Composition
title_short The fungal cell wall: candida, cryptococcus, and aspergillus species
title_full The fungal cell wall: candida, cryptococcus, and aspergillus species
title_fullStr The fungal cell wall: candida, cryptococcus, and aspergillus species
title_full_unstemmed The fungal cell wall: candida, cryptococcus, and aspergillus species
title_sort The fungal cell wall: candida, cryptococcus, and aspergillus species
author Garcia-Rubio, Rocio
author_facet Garcia-Rubio, Rocio
Oliveira, Haroldo Cesar de
Rivera, Johanna
Trevijano-Contador, Nuria
author_role author
author2 Oliveira, Haroldo Cesar de
Rivera, Johanna
Trevijano-Contador, Nuria
author2_role author
author
author
dc.contributor.author.fl_str_mv Garcia-Rubio, Rocio
Oliveira, Haroldo Cesar de
Rivera, Johanna
Trevijano-Contador, Nuria
dc.subject.en.en.fl_str_mv Cell wall
Candida
Cryptococcus
Aspergillus
Synthesis
Composition
topic Cell wall
Candida
Cryptococcus
Aspergillus
Synthesis
Composition
description Link para o artigo publicado: https://www.frontiersin.org/articles/10.3389/fmicb.2019.02993/full
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-12-11T15:02:20Z
dc.date.available.fl_str_mv 2020-12-11T15:02:20Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GARCIA-RUBIO, Rocio et al. The fungal cell wall: candida, cryptococcus, and aspergillus species. Frontiers Microbiology, v. 10, n. 2993, p. 1-13, 9 Jan. 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/44810
dc.identifier.issn.pt_BR.fl_str_mv 1664-302X
dc.identifier.doi.none.fl_str_mv 10.3389/fmicb.2019.02993
dc.identifier.eissn.none.fl_str_mv 1664-302X
identifier_str_mv GARCIA-RUBIO, Rocio et al. The fungal cell wall: candida, cryptococcus, and aspergillus species. Frontiers Microbiology, v. 10, n. 2993, p. 1-13, 9 Jan. 2020.
1664-302X
10.3389/fmicb.2019.02993
url https://www.arca.fiocruz.br/handle/icict/44810
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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