Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)

Detalhes bibliográficos
Autor(a) principal: Goldschmidt, Beatriz
Data de Publicação: 2017
Outros Autores: Calado, Monica I. Z., Resende, Felipe C., Caldas, Rodrigo, M., Pinto, Laine, Lopes, Claudia, França, F. G. O., Meireles, Barbara, Souza, Igo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/29132
Resumo: Fundação Oswaldo Cruz. Instituto de Ciência e Tecnologia em Biomodelos. Serviço de Criação de Primatas Não Humanos. Rio de Janeiro, RJ, Brasil.
id CRUZ_60d43fff6f6b18248d07c1082a4c9a58
oai_identifier_str oai:www.arca.fiocruz.br:icict/29132
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Goldschmidt, BeatrizCalado, Monica I. Z.Resende, Felipe C.Caldas, Rodrigo, M.Pinto, LaineLopes, ClaudiaFrança, F. G. O.Meireles, BarbaraSouza, Igo2018-09-27T19:02:59Z2018-09-27T19:02:59Z2017GOLDSCHMIDT, Beatriz et al. Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta). J. Med. Primatol., v. 46, p. 51–55, 2017.10.1111/jmp.12254https://www.arca.fiocruz.br/handle/icict/29132engWileySpontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto de Ciência e Tecnologia em Biomodelos. Serviço de Criação de Primatas Não Humanos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Ciência e Tecnologia em Biomodelos. Serviço de Criação de Primatas Não Humanos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Ciência e Tecnologia em Biomodelos. Serviço de Criação de Primatas Não Humanos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.Instituto Nacional de Câncer. Divisão de Patologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Ciência e Tecnologia em Biomodelos. Serviço de Criação de Primatas Não Humanos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Setor de Radiologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Ciência e Tecnologia em Biomodelos. Serviço de Criação de Primatas Não Humanos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Ciência e Tecnologia em Biomodelos. Serviço de Criação de Primatas Não Humanos. Rio de Janeiro, RJ, Brasil.Osteosarcoma (OS) is the most common type of bone cancer, especially in young. Telangiectatic osteosarcoma (TO) is a rare variant of OS, and hence, its occurrence, presentation, and prognosis are poorly understood. A 4-year-old female rhesus monkey presenting lameness and swelling was examined for a mass on the right humerus. Radiography revealed fracture and disorganized structure of bone tissue. Histopathological examination revealed malignant neoplasm composed of anaplastic osteoblasts, which invaded the bone marrow and surrounded blood-filled cysts in the epiphysis and diaphysis forming septa. Cytogenetic analysis showed aneuploid cells, supernumerary AgNORs, and a marker fragment. The neoplasm was diagnosed as TO. To our knowledge, the occurrence of TO and its cytogenetic analysis were reported for the first time in non-human primates.Bone CancerChromosomesNon-human PrimateOsteosarcomainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/29132/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALGoldschmidt_et_al-2017-Journal_of_Medical_Primatology.pdfGoldschmidt_et_al-2017-Journal_of_Medical_Primatology.pdfapplication/pdf710247https://www.arca.fiocruz.br/bitstream/icict/29132/2/Goldschmidt_et_al-2017-Journal_of_Medical_Primatology.pdfdd1de45473fe80acb9a317c8056b6530MD52TEXTGoldschmidt_et_al-2017-Journal_of_Medical_Primatology.pdf.txtGoldschmidt_et_al-2017-Journal_of_Medical_Primatology.pdf.txtExtracted texttext/plain20537https://www.arca.fiocruz.br/bitstream/icict/29132/3/Goldschmidt_et_al-2017-Journal_of_Medical_Primatology.pdf.txt76cdc00d3679286b1869004ad6670934MD53icict/291322018-11-24 22:03:04.873oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352018-11-25T00:03:04Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)
title Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)
spellingShingle Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)
Goldschmidt, Beatriz
Bone Cancer
Chromosomes
Non-human Primate
Osteosarcoma
title_short Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)
title_full Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)
title_fullStr Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)
title_full_unstemmed Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)
title_sort Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)
author Goldschmidt, Beatriz
author_facet Goldschmidt, Beatriz
Calado, Monica I. Z.
Resende, Felipe C.
Caldas, Rodrigo, M.
Pinto, Laine
Lopes, Claudia
França, F. G. O.
Meireles, Barbara
Souza, Igo
author_role author
author2 Calado, Monica I. Z.
Resende, Felipe C.
Caldas, Rodrigo, M.
Pinto, Laine
Lopes, Claudia
França, F. G. O.
Meireles, Barbara
Souza, Igo
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Goldschmidt, Beatriz
Calado, Monica I. Z.
Resende, Felipe C.
Caldas, Rodrigo, M.
Pinto, Laine
Lopes, Claudia
França, F. G. O.
Meireles, Barbara
Souza, Igo
dc.subject.en.pt_BR.fl_str_mv Bone Cancer
Chromosomes
Non-human Primate
Osteosarcoma
topic Bone Cancer
Chromosomes
Non-human Primate
Osteosarcoma
description Fundação Oswaldo Cruz. Instituto de Ciência e Tecnologia em Biomodelos. Serviço de Criação de Primatas Não Humanos. Rio de Janeiro, RJ, Brasil.
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2018-09-27T19:02:59Z
dc.date.available.fl_str_mv 2018-09-27T19:02:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GOLDSCHMIDT, Beatriz et al. Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta). J. Med. Primatol., v. 46, p. 51–55, 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/29132
dc.identifier.issn.pt_BR.fl_str_mv 10.1111/jmp.12254
identifier_str_mv GOLDSCHMIDT, Beatriz et al. Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta). J. Med. Primatol., v. 46, p. 51–55, 2017.
10.1111/jmp.12254
url https://www.arca.fiocruz.br/handle/icict/29132
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/29132/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/29132/2/Goldschmidt_et_al-2017-Journal_of_Medical_Primatology.pdf
https://www.arca.fiocruz.br/bitstream/icict/29132/3/Goldschmidt_et_al-2017-Journal_of_Medical_Primatology.pdf.txt
bitstream.checksum.fl_str_mv 5a560609d32a3863062d77ff32785d58
dd1de45473fe80acb9a317c8056b6530
76cdc00d3679286b1869004ad6670934
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813008861770022912

Registros relacionados