COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances

Detalhes bibliográficos
Autor(a) principal: Belchior-Bezerra, Mayara
Data de Publicação: 2022
Outros Autores: Lima, Rafael Silva, Medeiros, Nayara Ingrid, Gomes, Juliana Assis Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/56758
Resumo: Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brazil.
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spelling Belchior-Bezerra, MayaraLima, Rafael SilvaMedeiros, Nayara IngridGomes, Juliana Assis Silva2023-01-30T16:19:44Z2023-01-30T16:19:44Z2022COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances. Obes Rev., v. 23, n. 10, e13496, 2022. doi: 10.1111/obr.13496.1467-7881https://www.arca.fiocruz.br/handle/icict/56758engBlackwell PublishingCOVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advancesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brazil/Fundação Oswaldo Cruz. Instituto René Rachou. Imunologia Celular e Molecular. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brazil.In the 2 years since the COVID-19 pandemic was officially declared, science has made considerable strides in understanding the disease's pathophysiology, pharmacological treatments, immune response, and vaccination, but there is still much room for further advances, especially in comprehending its relationship with obesity. Science has not yet described the mechanisms that explain how obesity is directly associated with a poor prognosis. This paper gathers all published studies over the past 2 years that have described immune response, obesity, and COVID-19, a historical and chronological record for researchers and the general public alike. In summary, these studies describe how the cytokine/adipokine levels and inflammatory markers, such as the C-reactive protein, are associated with a higher body mass index in COVID-19-positive patients, suggesting that the inflammatory background and immune dysregulation in individuals with obesity may be expressed in the results and that adiposity may influence the immune response. The timeline presented here is a compilation of the results of 2 years of scientific inquiry, describing how the science has progressed, the principal findings, and the challenges ahead regarding SARS-CoV-2, COVID-19, and emerging variants, especially in patients with obesity.COVID-19immune responseobesityscientific advancesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/56758/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCOVID‐19, obesity, and immune response 2 years after the pandemic_ A timeline of scientific advances.pdfCOVID‐19, obesity, and immune response 2 years after the pandemic_ A timeline of scientific 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dc.title.en_US.fl_str_mv COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances
title COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances
spellingShingle COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances
Belchior-Bezerra, Mayara
COVID-19
immune response
obesity
scientific advances
title_short COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances
title_full COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances
title_fullStr COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances
title_full_unstemmed COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances
title_sort COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances
author Belchior-Bezerra, Mayara
author_facet Belchior-Bezerra, Mayara
Lima, Rafael Silva
Medeiros, Nayara Ingrid
Gomes, Juliana Assis Silva
author_role author
author2 Lima, Rafael Silva
Medeiros, Nayara Ingrid
Gomes, Juliana Assis Silva
author2_role author
author
author
dc.contributor.author.fl_str_mv Belchior-Bezerra, Mayara
Lima, Rafael Silva
Medeiros, Nayara Ingrid
Gomes, Juliana Assis Silva
dc.subject.en.en_US.fl_str_mv COVID-19
immune response
obesity
scientific advances
topic COVID-19
immune response
obesity
scientific advances
description Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brazil.
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-01-30T16:19:44Z
dc.date.available.fl_str_mv 2023-01-30T16:19:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances. Obes Rev., v. 23, n. 10, e13496, 2022. doi: 10.1111/obr.13496.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/56758
dc.identifier.issn.en_US.fl_str_mv 1467-7881
identifier_str_mv COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances. Obes Rev., v. 23, n. 10, e13496, 2022. doi: 10.1111/obr.13496.
1467-7881
url https://www.arca.fiocruz.br/handle/icict/56758
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Blackwell Publishing
publisher.none.fl_str_mv Blackwell Publishing
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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