Obesity, immune system dysfunction and implications for Covid-19: a literature review
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Health Review |
Texto Completo: | https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/56836 |
Resumo: | Obesity is a chronic low-grade inflammatory disease in which hypertrophy is followed by adipocyte apoptosis. These cells, which act as an endocrine organ, initiate increased secretion of pro-inflammatory cytokines and reduced anti-inflammatory cytokines, resulting in compromised immune system and advancement of infection to a systemic level. In addition, fat accumulation negatively affects the cardiovascular and respiratory systems. Thus, in the context of the pandemic COVID -19, the obese individual, who has an immune deficiency and a restrictive respiratory pattern, becomes more prone to a worse prognosis for the disease. Methodology is review was conducted on PubMed-indexed scientific literature database platforms with no time or language limits (update January 2021) Objective: elucidates the impact of obesity on the immune pattern and prognosis of COVID -19. Result: It was described on findings divided into Obesity vs Immune System; Obesity vs COVID -19. Conclusion; thus, knowledge of the impact of obesity on the immune system as well as implementation of therapeutic measures to reduce it are critical in the current coronavirus scenario. |
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Brazilian Journal of Health Review |
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Obesity, immune system dysfunction and implications for Covid-19: a literature reviewObesityimmune systemCOVID -19inflammationObesity is a chronic low-grade inflammatory disease in which hypertrophy is followed by adipocyte apoptosis. These cells, which act as an endocrine organ, initiate increased secretion of pro-inflammatory cytokines and reduced anti-inflammatory cytokines, resulting in compromised immune system and advancement of infection to a systemic level. In addition, fat accumulation negatively affects the cardiovascular and respiratory systems. Thus, in the context of the pandemic COVID -19, the obese individual, who has an immune deficiency and a restrictive respiratory pattern, becomes more prone to a worse prognosis for the disease. Methodology is review was conducted on PubMed-indexed scientific literature database platforms with no time or language limits (update January 2021) Objective: elucidates the impact of obesity on the immune pattern and prognosis of COVID -19. Result: It was described on findings divided into Obesity vs Immune System; Obesity vs COVID -19. Conclusion; thus, knowledge of the impact of obesity on the immune system as well as implementation of therapeutic measures to reduce it are critical in the current coronavirus scenario.Brazilian Journals Publicações de Periódicos e Editora Ltda.2023-01-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/5683610.34119/bjhrv6n1-186Brazilian Journal of Health Review; Vol. 6 No. 1 (2023); 2380-2391Brazilian Journal of Health Review; Vol. 6 Núm. 1 (2023); 2380-2391Brazilian Journal of Health Review; v. 6 n. 1 (2023); 2380-23912595-6825reponame:Brazilian Journal of Health Reviewinstname:Federação das Indústrias do Estado do Paraná (FIEP)instacron:BJRHenghttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/56836/41682Miguel, Isadora DallarmiArcie, Gabriella MaraPascholatto, Khadija AssisSaito, Rafael TadashiSapia, Emyliana BelinatiCavalheiro, Gabriel RodrigoBetim, Fernando Cesar MartinsFernandes, Idonilton da ConceiçãoMiguel, Obdulio Gomesinfo:eu-repo/semantics/openAccess2023-02-15T18:17:56Zoai:ojs2.ojs.brazilianjournals.com.br:article/56836Revistahttp://www.brazilianjournals.com/index.php/BJHR/indexPRIhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/oai|| brazilianjhr@gmail.com2595-68252595-6825opendoar:2023-02-15T18:17:56Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP)false |
dc.title.none.fl_str_mv |
Obesity, immune system dysfunction and implications for Covid-19: a literature review |
title |
Obesity, immune system dysfunction and implications for Covid-19: a literature review |
spellingShingle |
Obesity, immune system dysfunction and implications for Covid-19: a literature review Miguel, Isadora Dallarmi Obesity immune system COVID -19 inflammation |
title_short |
Obesity, immune system dysfunction and implications for Covid-19: a literature review |
title_full |
Obesity, immune system dysfunction and implications for Covid-19: a literature review |
title_fullStr |
Obesity, immune system dysfunction and implications for Covid-19: a literature review |
title_full_unstemmed |
Obesity, immune system dysfunction and implications for Covid-19: a literature review |
title_sort |
Obesity, immune system dysfunction and implications for Covid-19: a literature review |
author |
Miguel, Isadora Dallarmi |
author_facet |
Miguel, Isadora Dallarmi Arcie, Gabriella Mara Pascholatto, Khadija Assis Saito, Rafael Tadashi Sapia, Emyliana Belinati Cavalheiro, Gabriel Rodrigo Betim, Fernando Cesar Martins Fernandes, Idonilton da Conceição Miguel, Obdulio Gomes |
author_role |
author |
author2 |
Arcie, Gabriella Mara Pascholatto, Khadija Assis Saito, Rafael Tadashi Sapia, Emyliana Belinati Cavalheiro, Gabriel Rodrigo Betim, Fernando Cesar Martins Fernandes, Idonilton da Conceição Miguel, Obdulio Gomes |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Miguel, Isadora Dallarmi Arcie, Gabriella Mara Pascholatto, Khadija Assis Saito, Rafael Tadashi Sapia, Emyliana Belinati Cavalheiro, Gabriel Rodrigo Betim, Fernando Cesar Martins Fernandes, Idonilton da Conceição Miguel, Obdulio Gomes |
dc.subject.por.fl_str_mv |
Obesity immune system COVID -19 inflammation |
topic |
Obesity immune system COVID -19 inflammation |
description |
Obesity is a chronic low-grade inflammatory disease in which hypertrophy is followed by adipocyte apoptosis. These cells, which act as an endocrine organ, initiate increased secretion of pro-inflammatory cytokines and reduced anti-inflammatory cytokines, resulting in compromised immune system and advancement of infection to a systemic level. In addition, fat accumulation negatively affects the cardiovascular and respiratory systems. Thus, in the context of the pandemic COVID -19, the obese individual, who has an immune deficiency and a restrictive respiratory pattern, becomes more prone to a worse prognosis for the disease. Methodology is review was conducted on PubMed-indexed scientific literature database platforms with no time or language limits (update January 2021) Objective: elucidates the impact of obesity on the immune pattern and prognosis of COVID -19. Result: It was described on findings divided into Obesity vs Immune System; Obesity vs COVID -19. Conclusion; thus, knowledge of the impact of obesity on the immune system as well as implementation of therapeutic measures to reduce it are critical in the current coronavirus scenario. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-01-27 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/56836 10.34119/bjhrv6n1-186 |
url |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/56836 |
identifier_str_mv |
10.34119/bjhrv6n1-186 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/56836/41682 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
dc.source.none.fl_str_mv |
Brazilian Journal of Health Review; Vol. 6 No. 1 (2023); 2380-2391 Brazilian Journal of Health Review; Vol. 6 Núm. 1 (2023); 2380-2391 Brazilian Journal of Health Review; v. 6 n. 1 (2023); 2380-2391 2595-6825 reponame:Brazilian Journal of Health Review instname:Federação das Indústrias do Estado do Paraná (FIEP) instacron:BJRH |
instname_str |
Federação das Indústrias do Estado do Paraná (FIEP) |
instacron_str |
BJRH |
institution |
BJRH |
reponame_str |
Brazilian Journal of Health Review |
collection |
Brazilian Journal of Health Review |
repository.name.fl_str_mv |
Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP) |
repository.mail.fl_str_mv |
|| brazilianjhr@gmail.com |
_version_ |
1797240025662881792 |