Epidemiology of sepsis in Brazil: incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015

Detalhes bibliográficos
Autor(a) principal: Neira, Ricardo Alfredo Quintano
Data de Publicação: 2018
Outros Autores: Hamacher, Silvio, Japiassú, André Miguel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32341
Resumo: Pontifícia Universidade Católica do Rio de Janeiro. Industrial Engineering Department. Rio de Janeiro, RJ, Brasil / Philips Research Brazil. Barueri, SP, Brazil.
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spelling Neira, Ricardo Alfredo QuintanoHamacher, SilvioJapiassú, André Miguel2019-04-03T02:04:48Z2019-04-03T02:04:48Z2018NEIRA, Ricardo Alfredo Quintano; HAMACHER, Silvio; JAPIASSÚ, André Miguel. Epidemiology of sepsis in Brazil: Incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015. Plos One, p. 1-15, Apr. 13, 2018.1932-6203https://www.arca.fiocruz.br/handle/icict/3234110.1371/journal.pone.01958731932-6203engPublic Library of ScienceEpidemiology of sepsis in Brazil: incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlePontifícia Universidade Católica do Rio de Janeiro. Industrial Engineering Department. Rio de Janeiro, RJ, Brasil / Philips Research Brazil. Barueri, SP, Brazil.Pontifícia Universidade Católica do Rio de Janeiro. Industrial Engineering Department. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Background: Sepsis is considered a major worldwide health burden, with high mortality and associated costs. Health indicators are essential to define strategies to improve the treatment of diseases, and the epidemiology information of sepsis in developing countries is scarce. Thus, the aim of this work is to assess trends in the incidence, lethality, costs, and other indicators of sepsis for Brazilian Unified Health System (SUS—Sistema Único de Saúde) hospitalizations for the period from January 2006 to December 2015. Materials and methods: We conducted this study using data from the SUS hospital information system. We selected registries of SUS hospitalizations of patients diagnosed with sepsis (total of 724,458 cases from 4,271 public and private Brazilian hospitals). Results: From 2006 to 2015, the annual sepsis incidence increased 50.5% from 31.5/100,000 to 47.4/100,000 persons. The mean hospital length of stay (LOS) was 9.0 days. A total of 29.1% of the hospitalizations had admission to the intensive care unit (ICU) with a mean ICU LOS of 8.0 days. The mean cost per hospitalization was US$624.0 and for hospitalizations requiring intensive care was U$1,708.1. The overall sepsis lethality rate was 46.3%, and for hospitalizations with admission to the ICU, it was 64.5%. During the study period, the lethality rate for children/teenagers decreased 40.1%, but for all other age groups it increased 11.4%. The sepsis lethality rate in public hospitals (55.5%) was higher than private hospitals (37.0%) (p < 0.001). The mean hospitalization LOS for public hospitals (10.3 days) was higher than private hospitals (7.6 days) (p < 0.001). Conclusions: The incidence and lethality rate of sepsis increased in SUS hospitalizations during the study period. The SUS’s low reimbursement to hospitals for treating sepsis may be one of the reasons for the high lethality rate.SepsisEpidemiologyBrazilBrazilian Unified Health Systeminfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/32341/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Neira_Ricardo_etal_INI_2018.pdfve_Neira_Ricardo_etal_INI_2018.pdfapplication/pdf2775752https://www.arca.fiocruz.br/bitstream/icict/32341/2/ve_Neira_Ricardo_etal_INI_2018.pdf0efd913e64746e4bae5a6074cb98c756MD52TEXTve_Neira_Ricardo_etal_INI_2018.pdf.txtve_Neira_Ricardo_etal_INI_2018.pdf.txtExtracted texttext/plain49996https://www.arca.fiocruz.br/bitstream/icict/32341/3/ve_Neira_Ricardo_etal_INI_2018.pdf.txt8ed8f0184b7eb7851a02dd8214ee7959MD53icict/323412019-04-04 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dc.title.pt_BR.fl_str_mv Epidemiology of sepsis in Brazil: incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015
title Epidemiology of sepsis in Brazil: incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015
spellingShingle Epidemiology of sepsis in Brazil: incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015
Neira, Ricardo Alfredo Quintano
Sepsis
Epidemiology
Brazil
Brazilian Unified Health System
title_short Epidemiology of sepsis in Brazil: incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015
title_full Epidemiology of sepsis in Brazil: incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015
title_fullStr Epidemiology of sepsis in Brazil: incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015
title_full_unstemmed Epidemiology of sepsis in Brazil: incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015
title_sort Epidemiology of sepsis in Brazil: incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015
author Neira, Ricardo Alfredo Quintano
author_facet Neira, Ricardo Alfredo Quintano
Hamacher, Silvio
Japiassú, André Miguel
author_role author
author2 Hamacher, Silvio
Japiassú, André Miguel
author2_role author
author
dc.contributor.author.fl_str_mv Neira, Ricardo Alfredo Quintano
Hamacher, Silvio
Japiassú, André Miguel
dc.subject.en.pt_BR.fl_str_mv Sepsis
Epidemiology
Brazil
Brazilian Unified Health System
topic Sepsis
Epidemiology
Brazil
Brazilian Unified Health System
description Pontifícia Universidade Católica do Rio de Janeiro. Industrial Engineering Department. Rio de Janeiro, RJ, Brasil / Philips Research Brazil. Barueri, SP, Brazil.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-04-03T02:04:48Z
dc.date.available.fl_str_mv 2019-04-03T02:04:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv NEIRA, Ricardo Alfredo Quintano; HAMACHER, Silvio; JAPIASSÚ, André Miguel. Epidemiology of sepsis in Brazil: Incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015. Plos One, p. 1-15, Apr. 13, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32341
dc.identifier.issn.pt_BR.fl_str_mv 1932-6203
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pone.0195873
dc.identifier.eissn.none.fl_str_mv 1932-6203
identifier_str_mv NEIRA, Ricardo Alfredo Quintano; HAMACHER, Silvio; JAPIASSÚ, André Miguel. Epidemiology of sepsis in Brazil: Incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015. Plos One, p. 1-15, Apr. 13, 2018.
1932-6203
10.1371/journal.pone.0195873
url https://www.arca.fiocruz.br/handle/icict/32341
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/32341/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/32341/2/ve_Neira_Ricardo_etal_INI_2018.pdf
https://www.arca.fiocruz.br/bitstream/icict/32341/3/ve_Neira_Ricardo_etal_INI_2018.pdf.txt
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