Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.

Detalhes bibliográficos
Autor(a) principal: McBride, Alan John Alexander
Data de Publicação: 2007
Outros Autores: Pereira, Fernanda Albuquerque, Silva, Emilson Domingos da, Matos, Rosan B. de, Silva, Edimilson Domingos da, Ferreira, Antonio Gomes Pinto, Reis, Mitermayer Galvão dos, Ko, Albert Icksang
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7546
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
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spelling McBride, Alan John AlexanderPereira, Fernanda AlbuquerqueSilva, Emilson Domingos daMatos, Rosan B. deSilva, Edimilson Domingos daFerreira, Antonio Gomes PintoReis, Mitermayer Galvão dosKo, Albert Icksang2014-04-25T18:49:40Z2014-04-25T18:49:40Z2007McBRIDE, A. j. A. et al. Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. Acta Tropica, v. 102, n. 3, p. 206-211, 2007.0001-706Xhttps://www.arca.fiocruz.br/handle/icict/7546engNational Institute of HealthEvaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Division of International Medicine and Infectious Disease. Weill Medical College of Cornell University. New York, USAAccess to low-cost, effective diagnosis for leptospirosis is urgently needed in developing countries. The EIE-IgM-Leptospirose, a kit produced for public health laboratories in Brazil, was shown to have a sensitivity of 76% (77 of 102 patients) and 100% (102 of 102 patients) during acute and convalescent-phase leptospirosis, respectively, and a specificity of 93-100% (total healthy and patient control subjects evaluated, 486). These findings indicate that the assay will be useful for diagnosis of this emerging infectious disease in Brazil and other developing countries.IgM ELISADiagnosisEpidemicsUrbanserovarLeptospiraCopenhageniBrazilEnsaio de Imunoadsorção EnzimáticaImunoglobulina M/análiseLeptospirose/diagnósticoLeptospirose/imunologiaKit de Reagentes para DiagnósticoBrasil/epidemiologiaHumanosLeptospirose/epidemiologiaSensibilidade e EspecificidadeTestes Sorológicosinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALMcBRIDE AJA Evaluation of the EIE-Igm......pdfMcBRIDE AJA Evaluation of the EIE-Igm......pdfapplication/pdf336093https://www.arca.fiocruz.br/bitstream/icict/7546/1/McBRIDE%20AJA%20Evaluation%20of%20the%20EIE-Igm......pdfe940bd79db5b0665ca7af5562adbd1e3MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7546/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTMcBRIDE AJA Evaluation of the EIE-Igm......pdf.txtMcBRIDE AJA Evaluation of the EIE-Igm......pdf.txtExtracted texttext/plain27414https://www.arca.fiocruz.br/bitstream/icict/7546/5/McBRIDE%20AJA%20Evaluation%20of%20the%20EIE-Igm......pdf.txtacfdc677903990f4174a5a4217e79782MD55THUMBNAILMcBRIDE AJA Evaluation of the EIE-Igm......pdf.jpgMcBRIDE AJA Evaluation of the EIE-Igm......pdf.jpgGenerated Thumbnailimage/jpeg2420https://www.arca.fiocruz.br/bitstream/icict/7546/4/McBRIDE%20AJA%20Evaluation%20of%20the%20EIE-Igm......pdf.jpg90349154b34a5d1cd9b61160947a68c1MD54icict/75462023-03-15 14:33:18.944oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:18Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
title Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
spellingShingle Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
McBride, Alan John Alexander
IgM ELISA
Diagnosis
Epidemics
Urban
serovar
Leptospira
Copenhageni
Brazil
Ensaio de Imunoadsorção Enzimática
Imunoglobulina M/análise
Leptospirose/diagnóstico
Leptospirose/imunologia
Kit de Reagentes para Diagnóstico
Brasil/epidemiologia
Humanos
Leptospirose/epidemiologia
Sensibilidade e Especificidade
Testes Sorológicos
title_short Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
title_full Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
title_fullStr Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
title_full_unstemmed Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
title_sort Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
author McBride, Alan John Alexander
author_facet McBride, Alan John Alexander
Pereira, Fernanda Albuquerque
Silva, Emilson Domingos da
Matos, Rosan B. de
Silva, Edimilson Domingos da
Ferreira, Antonio Gomes Pinto
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
author_role author
author2 Pereira, Fernanda Albuquerque
Silva, Emilson Domingos da
Matos, Rosan B. de
Silva, Edimilson Domingos da
Ferreira, Antonio Gomes Pinto
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv McBride, Alan John Alexander
Pereira, Fernanda Albuquerque
Silva, Emilson Domingos da
Matos, Rosan B. de
Silva, Edimilson Domingos da
Ferreira, Antonio Gomes Pinto
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
dc.subject.en.pt_BR.fl_str_mv IgM ELISA
Diagnosis
Epidemics
Urban
serovar
Leptospira
Copenhageni
Brazil
topic IgM ELISA
Diagnosis
Epidemics
Urban
serovar
Leptospira
Copenhageni
Brazil
Ensaio de Imunoadsorção Enzimática
Imunoglobulina M/análise
Leptospirose/diagnóstico
Leptospirose/imunologia
Kit de Reagentes para Diagnóstico
Brasil/epidemiologia
Humanos
Leptospirose/epidemiologia
Sensibilidade e Especificidade
Testes Sorológicos
dc.subject.decs.pt_BR.fl_str_mv Ensaio de Imunoadsorção Enzimática
Imunoglobulina M/análise
Leptospirose/diagnóstico
Leptospirose/imunologia
Kit de Reagentes para Diagnóstico
Brasil/epidemiologia
Humanos
Leptospirose/epidemiologia
Sensibilidade e Especificidade
Testes Sorológicos
description Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2014-04-25T18:49:40Z
dc.date.available.fl_str_mv 2014-04-25T18:49:40Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv McBRIDE, A. j. A. et al. Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. Acta Tropica, v. 102, n. 3, p. 206-211, 2007.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7546
dc.identifier.issn.none.fl_str_mv 0001-706X
identifier_str_mv McBRIDE, A. j. A. et al. Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. Acta Tropica, v. 102, n. 3, p. 206-211, 2007.
0001-706X
url https://www.arca.fiocruz.br/handle/icict/7546
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language eng
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dc.publisher.none.fl_str_mv National Institute of Health
publisher.none.fl_str_mv National Institute of Health
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