Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo de conferência |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/23313 |
Resumo: | Introduction: There is a need for improved diagnostics since standard tests for leptospirosis are not widely accessible and have low sensitivity during early-phase illness. Lig proteins were shown to be highperforming serodiagnostic markers for leptospirosis in immunoblot and ELISA studies. In this study, we evaluated the feasibility of developing a rapid Lig protein-based assay. |
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Medeiros, Marco AlbertoCarolina L. AquinoSilva, Edimilson Domingos daRibeiro, Guilherme de SousaCouceiro, Eliane dos Santos SilvaPinto, Antonio G.Esfandiari, JavanLyashchenko, KonstantinReis, Mitermayer Galvão dosKo, Albert Icksang2017-11-22T19:05:09Z2017-11-22T19:05:09Z2010MEDEIROS, Marco Alberto et al. Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay. In: CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 46., 2010, Foz do Iguaçu, Paraná. Anais ... Foz do Iguaçu, Paraná: Sociedade Brasileira de Medicina Tropical, 2010. 1 p.https://www.arca.fiocruz.br/handle/icict/23313Introduction: There is a need for improved diagnostics since standard tests for leptospirosis are not widely accessible and have low sensitivity during early-phase illness. Lig proteins were shown to be highperforming serodiagnostic markers for leptospirosis in immunoblot and ELISA studies. In this study, we evaluated the feasibility of developing a rapid Lig protein-based assay.Fundação Oswaldo Cruz. Biomanguinhos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Biomanguinhos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Biomanguinhos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Biomanguinhos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Biomanguinhos. Rio de Janeiro, RJ, Brasil / Universidade Federal da Bahia. Salvador, BA, Brasil.Chembio Diagnostics Inc. USA.Chembio Diagnostics Inc. USA.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Ministério da Saúde. Brasília, DF, Brasil / Weill Medical College of Cornell University. 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dc.title.pt_BR.fl_str_mv |
Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay |
title |
Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay |
spellingShingle |
Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay Medeiros, Marco Alberto Leptospirose Leptospira Interrogans Proteina Diagnóstico Leptospirosis Leptospira Interrogans Protein Diagnosis |
title_short |
Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay |
title_full |
Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay |
title_fullStr |
Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay |
title_full_unstemmed |
Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay |
title_sort |
Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay |
author |
Medeiros, Marco Alberto |
author_facet |
Medeiros, Marco Alberto Carolina L. Aquino Silva, Edimilson Domingos da Ribeiro, Guilherme de Sousa Couceiro, Eliane dos Santos Silva Pinto, Antonio G. Esfandiari, Javan Lyashchenko, Konstantin Reis, Mitermayer Galvão dos Ko, Albert Icksang |
author_role |
author |
author2 |
Carolina L. Aquino Silva, Edimilson Domingos da Ribeiro, Guilherme de Sousa Couceiro, Eliane dos Santos Silva Pinto, Antonio G. Esfandiari, Javan Lyashchenko, Konstantin Reis, Mitermayer Galvão dos Ko, Albert Icksang |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Medeiros, Marco Alberto Carolina L. Aquino Silva, Edimilson Domingos da Ribeiro, Guilherme de Sousa Couceiro, Eliane dos Santos Silva Pinto, Antonio G. Esfandiari, Javan Lyashchenko, Konstantin Reis, Mitermayer Galvão dos Ko, Albert Icksang |
dc.subject.other.pt_BR.fl_str_mv |
Leptospirose Leptospira Interrogans Proteina Diagnóstico |
topic |
Leptospirose Leptospira Interrogans Proteina Diagnóstico Leptospirosis Leptospira Interrogans Protein Diagnosis |
dc.subject.en.pt_BR.fl_str_mv |
Leptospirosis Leptospira Interrogans Protein Diagnosis |
description |
Introduction: There is a need for improved diagnostics since standard tests for leptospirosis are not widely accessible and have low sensitivity during early-phase illness. Lig proteins were shown to be highperforming serodiagnostic markers for leptospirosis in immunoblot and ELISA studies. In this study, we evaluated the feasibility of developing a rapid Lig protein-based assay. |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010 |
dc.date.accessioned.fl_str_mv |
2017-11-22T19:05:09Z |
dc.date.available.fl_str_mv |
2017-11-22T19:05:09Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
format |
conferenceObject |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MEDEIROS, Marco Alberto et al. Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay. In: CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 46., 2010, Foz do Iguaçu, Paraná. Anais ... Foz do Iguaçu, Paraná: Sociedade Brasileira de Medicina Tropical, 2010. 1 p. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/23313 |
identifier_str_mv |
MEDEIROS, Marco Alberto et al. Rapid diagnosis of Leptospirosis: pilot evaluation of a Leptospiral immunoglobulin-like protein-based dual path Platform assay. In: CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 46., 2010, Foz do Iguaçu, Paraná. Anais ... Foz do Iguaçu, Paraná: Sociedade Brasileira de Medicina Tropical, 2010. 1 p. |
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https://www.arca.fiocruz.br/handle/icict/23313 |
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eng |
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eng |
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Sociedade Brasileira de Medicina Tropical |
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Sociedade Brasileira de Medicina Tropical |
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