Epidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazil

Detalhes bibliográficos
Autor(a) principal: Falqueto, A.
Data de Publicação: 2003
Outros Autores: Sessa, P. A., Ferreira, A. L., Vieira, V. P., Santos, C. B., Varejão, J. B. M., Cupolillo, E., Porrozzi, R., Paes, L. E. Carvalho, Grimaldi Jr., Gabriel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/19331
Resumo: Universidade Federal do Espírito Santo. Centro Biomédico. Departamento de Patologia. Unidade de Medicina Tropical. Vitória, ES, Brasil.
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spelling Falqueto, A.Sessa, P. A.Ferreira, A. L.Vieira, V. P.Santos, C. B.Varejão, J. B. M.Cupolillo, E.Porrozzi, R.Paes, L. E. CarvalhoGrimaldi Jr., Gabriel2017-06-06T17:40:23Z2017-06-06T17:40:23Z2003FALQUETO, A. et al. Epidemiological and Clinical Features of Leishmania (Viannia) braziliensis American Cutaneous and Mucocutaneous Leishmaniasis in the State of Espírito Santo, Brazil. Mem Inst Oswaldo Cruz, v.98, n.8, p.1003-1010, Dec. 2003.0074-0276https://www.arca.fiocruz.br/handle/icict/1933110.1590/S0074-027620030008000041678-8060engFundação Oswaldo Cruz. Instituto Oswaldo CruzLeishmania braziliensisLeishmaniose cutâneaEpidemiologia MolecularEspírito SantoBrasilLeishmania (Viannia) braziliensiscutaneous leishmaniasisMolecular EpidemiologyEspírito SantoBrazilEpidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Espírito Santo. Centro Biomédico. Departamento de Patologia. Unidade de Medicina Tropical. Vitória, ES, Brasil.Universidade Federal do Espírito Santo. Centro Biomédico. Departamento de Patologia. Unidade de Medicina Tropical. Vitória, ES, Brasil.Universidade Federal do Espírito Santo. Centro Biomédico. Departamento de Patologia. Unidade de Medicina Tropical. Vitória, ES, Brasil.Universidade Federal do Espírito Santo. Centro Biomédico. Departamento de Patologia. Unidade de Medicina Tropical. Vitória, ES, Brasil.Universidade Federal do Espírito Santo. Centro Biomédico. Departamento de Patologia. Unidade de Medicina Tropical. Vitória, ES, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ. Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultraestrutura e Biologia Celular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ. Brasil.Between 1985 and 2000, epidemiological surveys of the American tegumentary leishmaniasis (ATL) were carried out in several rural and urban communities in Espírito Santo, Brazil. A total of 100 stocks of Leishmania (comprising isolates from both human and canine hosts with ATL) were identified by two methods of molecular characterization, using specific monoclonal antibodies and multilocus enzyme electrophoresis. Parasite isolates from 19 municipalities were found to belong to the same zymodeme and serodeme type as of the Leishmania (Viannia) braziliensis reference strain. In contrast, our genotyping studies have shown intra-specific variation among these parasites (comparisons of the variability of the internal transcribed spacers between the small and large subunits of the rRNA genes of the 22 stocks studied revealed at least 11 genotypes). Two main clusters of L. (V.) braziliensis genotypes were observed, representing parasites collected from different endemic regions in the state, where transmission reflects distinct eco-epidemiological features. Infection with this pathogen was associated with the characteristic disease forms, but neither the clinical outcome nor the response to treatment could be related to the genetic polymorphism of the isolates, as defined by using the proposed methodology.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/19331/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALgabriel_grimaldijr4_etal_IOC_2003.pdfgabriel_grimaldijr4_etal_IOC_2003.pdfapplication/pdf99958https://www.arca.fiocruz.br/bitstream/icict/19331/2/gabriel_grimaldijr4_etal_IOC_2003.pdf1f53db7093eda987085aa020fc73558eMD52TEXTgabriel_grimaldijr4_etal_IOC_2003.pdf.txtgabriel_grimaldijr4_etal_IOC_2003.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Epidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazil
title Epidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazil
spellingShingle Epidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazil
Falqueto, A.
Leishmania braziliensis
Leishmaniose cutânea
Epidemiologia Molecular
Espírito Santo
Brasil
Leishmania (Viannia) braziliensis
cutaneous leishmaniasis
Molecular Epidemiology
Espírito Santo
Brazil
title_short Epidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazil
title_full Epidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazil
title_fullStr Epidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazil
title_full_unstemmed Epidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazil
title_sort Epidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazil
author Falqueto, A.
author_facet Falqueto, A.
Sessa, P. A.
Ferreira, A. L.
Vieira, V. P.
Santos, C. B.
Varejão, J. B. M.
Cupolillo, E.
Porrozzi, R.
Paes, L. E. Carvalho
Grimaldi Jr., Gabriel
author_role author
author2 Sessa, P. A.
Ferreira, A. L.
Vieira, V. P.
Santos, C. B.
Varejão, J. B. M.
Cupolillo, E.
Porrozzi, R.
Paes, L. E. Carvalho
Grimaldi Jr., Gabriel
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Falqueto, A.
Sessa, P. A.
Ferreira, A. L.
Vieira, V. P.
Santos, C. B.
Varejão, J. B. M.
Cupolillo, E.
Porrozzi, R.
Paes, L. E. Carvalho
Grimaldi Jr., Gabriel
dc.subject.other.pt_BR.fl_str_mv Leishmania braziliensis
Leishmaniose cutânea
Epidemiologia Molecular
Espírito Santo
Brasil
topic Leishmania braziliensis
Leishmaniose cutânea
Epidemiologia Molecular
Espírito Santo
Brasil
Leishmania (Viannia) braziliensis
cutaneous leishmaniasis
Molecular Epidemiology
Espírito Santo
Brazil
dc.subject.en.pt_BR.fl_str_mv Leishmania (Viannia) braziliensis
cutaneous leishmaniasis
Molecular Epidemiology
Espírito Santo
Brazil
description Universidade Federal do Espírito Santo. Centro Biomédico. Departamento de Patologia. Unidade de Medicina Tropical. Vitória, ES, Brasil.
publishDate 2003
dc.date.issued.fl_str_mv 2003
dc.date.accessioned.fl_str_mv 2017-06-06T17:40:23Z
dc.date.available.fl_str_mv 2017-06-06T17:40:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv FALQUETO, A. et al. Epidemiological and Clinical Features of Leishmania (Viannia) braziliensis American Cutaneous and Mucocutaneous Leishmaniasis in the State of Espírito Santo, Brazil. Mem Inst Oswaldo Cruz, v.98, n.8, p.1003-1010, Dec. 2003.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/19331
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762003000800004
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv FALQUETO, A. et al. Epidemiological and Clinical Features of Leishmania (Viannia) braziliensis American Cutaneous and Mucocutaneous Leishmaniasis in the State of Espírito Santo, Brazil. Mem Inst Oswaldo Cruz, v.98, n.8, p.1003-1010, Dec. 2003.
0074-0276
10.1590/S0074-02762003000800004
1678-8060
url https://www.arca.fiocruz.br/handle/icict/19331
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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