Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/44225 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. |
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Santos, Flavia Barreto dosMiagostovich, Marize PereiraNogueira, Rita Maria RibeiroEdgil, DiannaSchatzmayr, Hermann GonçalvesRiley, Lee W.Harris, Eva2020-10-27T14:07:27Z2020-10-27T14:07:27Z2002SANTOS, Flavia Barreto dos et al. Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n.7, p. 991-995, 2002.0074-0276https://www.arca.fiocruz.br/handle/icict/4422510.1590/S0074-027620020007000111678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Vírus da Dengue tipo 2Genoma completoBrasilDengue virus type 2Complete genomeBrazilComplete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Straininfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.University of California. School of Public Health. Division of Infectious Diseases. Berkeley, CA, USA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.University of California. School of Public Health. Division of Infectious Diseases. Berkeley, CA, USA.University of California. School of Public Health. Division of Infectious Diseases. Berkeley, CA, USA.In the last decade, dengue fever (DF) in Brazil has been recognized as an important public health problem, and an increasing number of dengue haemorrhagic fever (DHF) cases have been reported since the introduction of dengue virus type 2 (DEN-2) into the country in 1990. In order to analyze the complete genome sequence of a DEN2 Brazilian strain (BR64022/98), we designed primers to amplify contiguous segments of approximately 500 base pairs across the entire sequence of the viral genome. Twenty fragments amplified by reverse transcriptase-PCR were cloned, and the complete nucleotide and the deduced amino acid sequences were determined. This constitutes the first complete genetic characterization of a DEN-2 strain from Brazil. All amino acid changes differentiating strains related to the Asian/American-Asian genotype were observed in BR64022/98, indicating the Asiatic origin of the strain.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/44225/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALFlaviaBSantos_RtiaMNogueira_etal_IOC_2002.pdfFlaviaBSantos_RtiaMNogueira_etal_IOC_2002.pdfapplication/pdf54851https://www.arca.fiocruz.br/bitstream/icict/44225/2/FlaviaBSantos_RtiaMNogueira_etal_IOC_2002.pdf2c4db25e30833a493da0e602289801d7MD52TEXTFlaviaBSantos_RtiaMNogueira_etal_IOC_2002.pdf.txtFlaviaBSantos_RtiaMNogueira_etal_IOC_2002.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv |
Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain |
title |
Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain |
spellingShingle |
Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain Santos, Flavia Barreto dos Vírus da Dengue tipo 2 Genoma completo Brasil Dengue virus type 2 Complete genome Brazil |
title_short |
Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain |
title_full |
Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain |
title_fullStr |
Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain |
title_full_unstemmed |
Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain |
title_sort |
Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain |
author |
Santos, Flavia Barreto dos |
author_facet |
Santos, Flavia Barreto dos Miagostovich, Marize Pereira Nogueira, Rita Maria Ribeiro Edgil, Dianna Schatzmayr, Hermann Gonçalves Riley, Lee W. Harris, Eva |
author_role |
author |
author2 |
Miagostovich, Marize Pereira Nogueira, Rita Maria Ribeiro Edgil, Dianna Schatzmayr, Hermann Gonçalves Riley, Lee W. Harris, Eva |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Santos, Flavia Barreto dos Miagostovich, Marize Pereira Nogueira, Rita Maria Ribeiro Edgil, Dianna Schatzmayr, Hermann Gonçalves Riley, Lee W. Harris, Eva |
dc.subject.other.pt_BR.fl_str_mv |
Vírus da Dengue tipo 2 Genoma completo Brasil |
topic |
Vírus da Dengue tipo 2 Genoma completo Brasil Dengue virus type 2 Complete genome Brazil |
dc.subject.en.pt_BR.fl_str_mv |
Dengue virus type 2 Complete genome Brazil |
description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. |
publishDate |
2002 |
dc.date.issued.fl_str_mv |
2002 |
dc.date.accessioned.fl_str_mv |
2020-10-27T14:07:27Z |
dc.date.available.fl_str_mv |
2020-10-27T14:07:27Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SANTOS, Flavia Barreto dos et al. Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n.7, p. 991-995, 2002. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/44225 |
dc.identifier.issn.pt_BR.fl_str_mv |
0074-0276 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S0074-02762002000700011 |
dc.identifier.eissn.none.fl_str_mv |
1678-8060 |
identifier_str_mv |
SANTOS, Flavia Barreto dos et al. Complete Nucleotide Sequence Analysis of a Brazilian Dengue Virus Type 2 Strain. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n.7, p. 991-995, 2002. 0074-0276 10.1590/S0074-02762002000700011 1678-8060 |
url |
https://www.arca.fiocruz.br/handle/icict/44225 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. |
publisher.none.fl_str_mv |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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