Decellularized extracellular matrix: the role of this complex biomaterial in regeneration

Detalhes bibliográficos
Autor(a) principal: Paula, André Guilherme Portela de
Data de Publicação: 2023
Outros Autores: Lima, Jordana Dinorá de, Bastos, Thais Sibioni Berti, Czaikovski, Andressa Pacheco, Luz, Rebeca Bosso dos Santos, Yuasa, Bruna Sadae, Smanioto, Caio Cesar Souza, Robert, Anny Waloski, Braga, Tárcio Teodoro
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/60195
https://doi.org/10.1021/acsomega.2c06216
Resumo: Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil.
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spelling Paula, André Guilherme Portela deLima, Jordana Dinorá deBastos, Thais Sibioni BertiCzaikovski, Andressa PachecoLuz, Rebeca Bosso dos SantosYuasa, Bruna SadaeSmanioto, Caio Cesar SouzaRobert, Anny WaloskiBraga, Tárcio Teodoro2023-08-22T17:41:47Z2023-08-22T17:41:47Z2023PAULA, André Guilherme Portela de et al. Decellularized extracellular matrix: The role of this complex biomaterial in regeneration. ACS Omega, v. 8, p. 22256 -22267, 2023.2470-1343https://www.arca.fiocruz.br/handle/icict/60195https://doi.org/10.1021/acsomega.2c06216porAmerican Chemical SocietyTecidos DescelularizadosDecellularized TissuesAcellular DermisBiocompatible MaterialsTissue EngineeringDermis AcelularMateriales BiocompatiblesIngeniería de TejidosDerme acellulaireMatériaux biocompatiblesIngénierie tissulaireDerme AcelularMateriais BiocompatíveisEngenharia TecidualDecellularized extracellular matrix: the role of this complex biomaterial in regenerationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Biologia Básica de Células Tronco. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil. / Fundação Oswaldo Cruz. Instituto Carlos Chagas. Programa de Pós-Graduação em Biociências e Biotecnologia. Curitiba, PR, Brasil.Organ transplantation is understood as a technique where an organ from a donor patient is transferred to a recipient patient. This practice gained strength in the 20th century and ensured advances in areas of knowledge such as immunology and tissue engineering. The main problems that comprise the practice of transplants involve the demand for viable organs and immunological aspects related to organ rejection. In this review, we address advances in tissue engineering for reversing the current challenges of transplants, focusing on the possible use of decellularized tissues in tissue engineering. We address the interaction of acellular tissues with immune cells, especially macrophages and stem cells, due to their potential use in regenerative medicine. Our goal is to exhibit data that demonstrate the use of decellularized tissues as alternative biomaterials that can be applied clinically as partial or complete organ substitutes.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALacsomega.2c06216ok.pdfacsomega.2c06216ok.pdfapplication/pdf5330170https://www.arca.fiocruz.br/bitstream/icict/60195/2/acsomega.2c06216ok.pdf74ee54d449cd76339adc5991ecd60696MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/60195/1/license.txt5a560609d32a3863062d77ff32785d58MD51icict/601952023-08-22 14:41:48.952oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-08-22T17:41:48Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Decellularized extracellular matrix: the role of this complex biomaterial in regeneration
title Decellularized extracellular matrix: the role of this complex biomaterial in regeneration
spellingShingle Decellularized extracellular matrix: the role of this complex biomaterial in regeneration
Paula, André Guilherme Portela de
Tecidos Descelularizados
Decellularized Tissues
Acellular Dermis
Biocompatible Materials
Tissue Engineering
Dermis Acelular
Materiales Biocompatibles
Ingeniería de Tejidos
Derme acellulaire
Matériaux biocompatibles
Ingénierie tissulaire
Derme Acelular
Materiais Biocompatíveis
Engenharia Tecidual
title_short Decellularized extracellular matrix: the role of this complex biomaterial in regeneration
title_full Decellularized extracellular matrix: the role of this complex biomaterial in regeneration
title_fullStr Decellularized extracellular matrix: the role of this complex biomaterial in regeneration
title_full_unstemmed Decellularized extracellular matrix: the role of this complex biomaterial in regeneration
title_sort Decellularized extracellular matrix: the role of this complex biomaterial in regeneration
author Paula, André Guilherme Portela de
author_facet Paula, André Guilherme Portela de
Lima, Jordana Dinorá de
Bastos, Thais Sibioni Berti
Czaikovski, Andressa Pacheco
Luz, Rebeca Bosso dos Santos
Yuasa, Bruna Sadae
Smanioto, Caio Cesar Souza
Robert, Anny Waloski
Braga, Tárcio Teodoro
author_role author
author2 Lima, Jordana Dinorá de
Bastos, Thais Sibioni Berti
Czaikovski, Andressa Pacheco
Luz, Rebeca Bosso dos Santos
Yuasa, Bruna Sadae
Smanioto, Caio Cesar Souza
Robert, Anny Waloski
Braga, Tárcio Teodoro
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Paula, André Guilherme Portela de
Lima, Jordana Dinorá de
Bastos, Thais Sibioni Berti
Czaikovski, Andressa Pacheco
Luz, Rebeca Bosso dos Santos
Yuasa, Bruna Sadae
Smanioto, Caio Cesar Souza
Robert, Anny Waloski
Braga, Tárcio Teodoro
dc.subject.other.en_US.fl_str_mv Tecidos Descelularizados
topic Tecidos Descelularizados
Decellularized Tissues
Acellular Dermis
Biocompatible Materials
Tissue Engineering
Dermis Acelular
Materiales Biocompatibles
Ingeniería de Tejidos
Derme acellulaire
Matériaux biocompatibles
Ingénierie tissulaire
Derme Acelular
Materiais Biocompatíveis
Engenharia Tecidual
dc.subject.en.en_US.fl_str_mv Decellularized Tissues
Acellular Dermis
Biocompatible Materials
Tissue Engineering
dc.subject.es.en_US.fl_str_mv Dermis Acelular
Materiales Biocompatibles
Ingeniería de Tejidos
dc.subject.fr.en_US.fl_str_mv Derme acellulaire
Matériaux biocompatibles
Ingénierie tissulaire
dc.subject.decs.en_US.fl_str_mv Derme Acelular
Materiais Biocompatíveis
Engenharia Tecidual
description Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-08-22T17:41:47Z
dc.date.available.fl_str_mv 2023-08-22T17:41:47Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv PAULA, André Guilherme Portela de et al. Decellularized extracellular matrix: The role of this complex biomaterial in regeneration. ACS Omega, v. 8, p. 22256 -22267, 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/60195
dc.identifier.issn.en_US.fl_str_mv 2470-1343
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1021/acsomega.2c06216
identifier_str_mv PAULA, André Guilherme Portela de et al. Decellularized extracellular matrix: The role of this complex biomaterial in regeneration. ACS Omega, v. 8, p. 22256 -22267, 2023.
2470-1343
url https://www.arca.fiocruz.br/handle/icict/60195
https://doi.org/10.1021/acsomega.2c06216
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/60195/2/acsomega.2c06216ok.pdf
https://www.arca.fiocruz.br/bitstream/icict/60195/1/license.txt
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bitstream.checksumAlgorithm.fl_str_mv MD5
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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