Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure

Detalhes bibliográficos
Autor(a) principal: Power, Grace M.
Data de Publicação: 2020
Outros Autores: Francis, Suzanna C., Clemente, Nuria Sanchez, Vasconcelos, Zilton Farias Meira de, Brasil, Patricia, Nielsen-Saines, Karin, Brickley, Elizabeth B., Moreira, Maria E.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/45815
Resumo: London School of Hygiene & Tropical Medicine. Faculty of Infectious and Tropical Diseases. Department of Disease Control. London, UK / London School of Hygiene & Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK / University of Bristol. Bristol Medical School. Population Health Sciences. MRC Integrative Epidemiology Unit. Bristol, UK.
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spelling Power, Grace M.Francis, Suzanna C.Clemente, Nuria SanchezVasconcelos, Zilton Farias Meira deBrasil, PatriciaNielsen-Saines, KarinBrickley, Elizabeth B.Moreira, Maria E.2021-01-25T21:47:22Z2021-01-25T21:47:22Z2020POWER, Grace M. et al. Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure. Viruses, v. 12, n. 11, p. 1-21, 2020.1999-4915https://www.arca.fiocruz.br/handle/icict/4581510.3390/v12111342engMDPIExamining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposureinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleLondon School of Hygiene & Tropical Medicine. Faculty of Infectious and Tropical Diseases. Department of Disease Control. London, UK / London School of Hygiene & Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK / University of Bristol. Bristol Medical School. Population Health Sciences. MRC Integrative Epidemiology Unit. Bristol, UK.London School of Hygiene & Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK.Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Rio de Janeiro, RJ, Brasil / London School of Hygiene & Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.University of California. Pediatrics. Los Angeles, CA, USA.London School of Hygiene & Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Increased rates of Zika virus have been identified in economically deprived areas in Brazil at the population level; yet, the implications of the interaction between socioeconomic position and prenatal Zika virus exposure on adverse neurodevelopmental outcomes remains insufficiently evaluated at the individual level. Using data collected between September 2015 and September 2019 from 163 children with qRT-PCR and/or IgM-confirmed prenatal exposure to Zika virus participating in a prospective cohort study in Rio de Janeiro, Brazil (NCT03255369), this study evaluated the relationships of socioeconomic indicators with microcephaly at birth and Bayley-III neurodevelopmental scores during the early life course. Adjusted logistic regression models indicated increased odds of microcephaly in children born to families with lower household income (OR, 95% CI: 3.85, 1.43 to 10.37) and higher household crowding (OR, 95% CI: 1.83, 1.16 to 2.91), while maternal secondary and higher education appeared to have a protective effect for microcephaly compared to primary education (OR, 95% CI: 0.33, 0.11 to 0.98 and 0.10, 0.03 to 0.36, respectively). Consistent with these findings, adjusted linear regression models indicated lower composite language (-10.78, 95% CI: -19.87 to -1.69), motor (-10.45, 95% CI: -19.22 to -1.69), and cognitive (-17.20, 95% CI: -26.13 to -8.28) scores in children whose families participated in the Bolsa Família social protection programme. As such, the results from this investigation further emphasise the detrimental effects of childhood disadvantage on human health and development by providing novel evidence on the link between individual level socioeconomic indicators and microcephaly and delayed early life neurodevelopment following prenatal Zika virus exposure.Zika virusCongenital Zika syndromeHealth equityMicrocephalyNeurodevelopmentSocioeconomic positioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure
title Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure
spellingShingle Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure
Power, Grace M.
Zika virus
Congenital Zika syndrome
Health equity
Microcephaly
Neurodevelopment
Socioeconomic position
title_short Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure
title_full Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure
title_fullStr Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure
title_full_unstemmed Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure
title_sort Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure
author Power, Grace M.
author_facet Power, Grace M.
Francis, Suzanna C.
Clemente, Nuria Sanchez
Vasconcelos, Zilton Farias Meira de
Brasil, Patricia
Nielsen-Saines, Karin
Brickley, Elizabeth B.
Moreira, Maria E.
author_role author
author2 Francis, Suzanna C.
Clemente, Nuria Sanchez
Vasconcelos, Zilton Farias Meira de
Brasil, Patricia
Nielsen-Saines, Karin
Brickley, Elizabeth B.
Moreira, Maria E.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Power, Grace M.
Francis, Suzanna C.
Clemente, Nuria Sanchez
Vasconcelos, Zilton Farias Meira de
Brasil, Patricia
Nielsen-Saines, Karin
Brickley, Elizabeth B.
Moreira, Maria E.
dc.subject.en.pt_BR.fl_str_mv Zika virus
Congenital Zika syndrome
Health equity
Microcephaly
Neurodevelopment
Socioeconomic position
topic Zika virus
Congenital Zika syndrome
Health equity
Microcephaly
Neurodevelopment
Socioeconomic position
description London School of Hygiene & Tropical Medicine. Faculty of Infectious and Tropical Diseases. Department of Disease Control. London, UK / London School of Hygiene & Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK / University of Bristol. Bristol Medical School. Population Health Sciences. MRC Integrative Epidemiology Unit. Bristol, UK.
publishDate 2020
dc.date.issued.fl_str_mv 2020
dc.date.accessioned.fl_str_mv 2021-01-25T21:47:22Z
dc.date.available.fl_str_mv 2021-01-25T21:47:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv POWER, Grace M. et al. Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure. Viruses, v. 12, n. 11, p. 1-21, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/45815
dc.identifier.issn.pt_BR.fl_str_mv 1999-4915
dc.identifier.doi.none.fl_str_mv 10.3390/v12111342
identifier_str_mv POWER, Grace M. et al. Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure. Viruses, v. 12, n. 11, p. 1-21, 2020.
1999-4915
10.3390/v12111342
url https://www.arca.fiocruz.br/handle/icict/45815
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/45815/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/45815/2/Examining_Maria_Moreira_etal_INI_2020.pdf
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