Lung in dengue: computed tomography findings
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/10589 |
Resumo: | D’Or Institute for Research and Education |
| id |
CRUZ_7363def9d3cc78d9527221d14f6d2c8d |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/10589 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Rodrigues, Rosana SouzaBrum, Ana Livia GarciaPaes, Marciano VianaPóvoa, Tiago FajardoOliveira, Carlos Alberto Basilio deMarchiori, EdsonBorghi, Danielle ProvençanoRamos, Grazielle VianaBozza, Fernando Augusto2015-06-01T16:13:18Z2015-06-01T16:13:18Z2014RODRIGUES, Rosana Souza et al. Lung in dengue: computed tomography findings. Plos One, v. 9, n. 5, p. 1-7, 2014.1932-6203https://www.arca.fiocruz.br/handle/icict/1058910.1371/journal.pone.00963131932-6203D’Or Institute for Research and EducationInstituto de Pesquisa e Educação D`Or. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Instituto de Pesquisa e Educação D`Or. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biotecnologia e Fisiologia de Infecções Virais. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biotecnologia e Fisiologia de Infecções Virais. Rio de Janeiro, RJ, Brasil.Universidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro, RJ, Brasil.Corpo de Bombeiros Militar do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Instituto de Pesquisa e Educação D`Or. Rio de Janeiro, RJ, Brasil.Background: Dengue is the most important mosquito-borne viral disease in the world. Dengue virus infection may be asymptomatic or lead to undifferentiated fever, dengue fever with or without warning signs, or severe dengue. Lower respiratory symptoms are unusual and lung-imaging data in patients with dengue are scarce. Methodology/Principal Findings: To evaluate lung changes associated with dengue infection, we retrospectively analyzed 2,020 confirmed cases of dengue. Twenty-nine of these patients (11 females and 18 males aged 16–90 years) underwent chest computed tomography (CT), which yielded abnormal findings in 17 patients: 16 patients had pleural effusion (the sole finding in six patients) and 11 patients had pulmonary abnormalities. Lung parenchyma involvement ranged from subtle to moderate unilateral and bilateral abnormalities. The most common finding was ground-glass opacity in eight patients, followed by consolidation in six patients. Less common findings were airspace nodules (two patients), interlobular septal thickening (two patients), and peribronchovascular interstitial thickening (one patient). Lung histopathological findings in four fatal cases showed thickening of the alveolar septa, hemorrhage, and interstitial edema. Conclusions/Significance: In this largest series involving the use of chest CT to evaluate lung involvement in patients with dengue, CT findings of lower respiratory tract involvement were uncommon. When abnormalities were present, pleural effusion was the most frequent finding and lung involvement was often mild or moderate and bilateral. Extensive lung abnormalities are infrequent even in severe disease and when present should lead physicians to consider other diagnostic possibilities.engPublic Library of ScienceLung in dengue: computed tomography findingsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleDengueSevere dengueLungX-ray computed tomographyDengueDengue gravePulmãoTomografia computadorizada por raios Xinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82352https://www.arca.fiocruz.br/bitstream/icict/10589/1/license.txtafbdf7d7a9bcf771a1cc7edf5f618413MD51ORIGINALLung in dengue Computed tomography findings.pdfLung in dengue Computed tomography findings.pdfapplication/pdf1101565https://www.arca.fiocruz.br/bitstream/icict/10589/2/Lung%20in%20dengue%20Computed%20tomography%20findings.pdf023c93df1d4ca3c0d57c4ba0a4fc57b5MD52TEXTLung in dengue Computed tomography findings.pdf.txtLung in dengue Computed tomography findings.pdf.txtExtracted texttext/plain34210https://www.arca.fiocruz.br/bitstream/icict/10589/3/Lung%20in%20dengue%20Computed%20tomography%20findings.pdf.txt7fce34c7255e9403e326b2803c822441MD53icict/105892023-09-14 16:02:06.247oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-14T19:02:06Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Lung in dengue: computed tomography findings |
| title |
Lung in dengue: computed tomography findings |
| spellingShingle |
Lung in dengue: computed tomography findings Rodrigues, Rosana Souza Dengue Severe dengue Lung X-ray computed tomography Dengue Dengue grave Pulmão Tomografia computadorizada por raios X |
| title_short |
Lung in dengue: computed tomography findings |
| title_full |
Lung in dengue: computed tomography findings |
| title_fullStr |
Lung in dengue: computed tomography findings |
| title_full_unstemmed |
Lung in dengue: computed tomography findings |
| title_sort |
Lung in dengue: computed tomography findings |
| author |
Rodrigues, Rosana Souza |
| author_facet |
Rodrigues, Rosana Souza Brum, Ana Livia Garcia Paes, Marciano Viana Póvoa, Tiago Fajardo Oliveira, Carlos Alberto Basilio de Marchiori, Edson Borghi, Danielle Provençano Ramos, Grazielle Viana Bozza, Fernando Augusto |
| author_role |
author |
| author2 |
Brum, Ana Livia Garcia Paes, Marciano Viana Póvoa, Tiago Fajardo Oliveira, Carlos Alberto Basilio de Marchiori, Edson Borghi, Danielle Provençano Ramos, Grazielle Viana Bozza, Fernando Augusto |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Rodrigues, Rosana Souza Brum, Ana Livia Garcia Paes, Marciano Viana Póvoa, Tiago Fajardo Oliveira, Carlos Alberto Basilio de Marchiori, Edson Borghi, Danielle Provençano Ramos, Grazielle Viana Bozza, Fernando Augusto |
| dc.subject.en.pt_BR.fl_str_mv |
Dengue Severe dengue Lung X-ray computed tomography |
| topic |
Dengue Severe dengue Lung X-ray computed tomography Dengue Dengue grave Pulmão Tomografia computadorizada por raios X |
| dc.subject.decs.pt_BR.fl_str_mv |
Dengue Dengue grave Pulmão Tomografia computadorizada por raios X |
| description |
D’Or Institute for Research and Education |
| publishDate |
2014 |
| dc.date.issued.fl_str_mv |
2014 |
| dc.date.accessioned.fl_str_mv |
2015-06-01T16:13:18Z |
| dc.date.available.fl_str_mv |
2015-06-01T16:13:18Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
RODRIGUES, Rosana Souza et al. Lung in dengue: computed tomography findings. Plos One, v. 9, n. 5, p. 1-7, 2014. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/10589 |
| dc.identifier.issn.none.fl_str_mv |
1932-6203 |
| dc.identifier.doi.none.fl_str_mv |
10.1371/journal.pone.0096313 |
| dc.identifier.eissn.none.fl_str_mv |
1932-6203 |
| identifier_str_mv |
RODRIGUES, Rosana Souza et al. Lung in dengue: computed tomography findings. Plos One, v. 9, n. 5, p. 1-7, 2014. 1932-6203 10.1371/journal.pone.0096313 |
| url |
https://www.arca.fiocruz.br/handle/icict/10589 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Public Library of Science |
| publisher.none.fl_str_mv |
Public Library of Science |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/10589/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/10589/2/Lung%20in%20dengue%20Computed%20tomography%20findings.pdf https://www.arca.fiocruz.br/bitstream/icict/10589/3/Lung%20in%20dengue%20Computed%20tomography%20findings.pdf.txt |
| bitstream.checksum.fl_str_mv |
afbdf7d7a9bcf771a1cc7edf5f618413 023c93df1d4ca3c0d57c4ba0a4fc57b5 7fce34c7255e9403e326b2803c822441 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1798324632117313536 |