Inflammatory cell infiltration and high antibody production in balb/c mice caused by natural exposure to Lutzomyia longipalpis bites
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2005 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/3239 |
Resumo: | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brazil |
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Silva, FrancinaldoGomes, Regis Bernardo BrandimPrates, Deboraci BritoMiranda, José CarlosAndrade, Bruno de BezerrilBarral Netto, ManoelBarral, Aldina Maria Prado2011-09-14T18:12:44Z2011-09-14T18:12:44Z2005SILVA, F. et al. Inflammatory cell infiltration and high antibody production in BALB/c mice caused by natural exposure to Lutzomyia longipalpis bites. American Journal of Tropical Medicine and Hygiene, v.72, n.1, p.94-98, jan. 2005.0002-9637https://www.arca.fiocruz.br/handle/icict/3239engInflammatory cell infiltration and high antibody production in balb/c mice caused by natural exposure to Lutzomyia longipalpis bitesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, BrazilSand flies inject saliva into the mammalian host when probing for a blood meal. Understanding the initial vertebrate reactions against sand fly saliva is important for possible interventions because these insects transmit diseases to humans and other animals. Little is known of these reactions to New World sand flies. Repeated exposure of BALB/c mice to Lutzomyia longipalpis bites leads to local inflammatory cell infiltration comprised of neutrophils, macrophages, and eosinophils. Total IgG and IgG1 antibodies react predominantly with three major protein bands (45, 44, and 16 kD) of the insect saliva by Western blot. The injection of immune serum previously incubated with salivary gland homogenate induced an early infiltration with neutrophils and macrophages, suggesting the participation of immune complexes in triggering inflammation.AnticorposMordeduras e Picadas de InsetosMacrófagosCamundongos Endogâmicos BALB CPsychodidaeSalivaLinfócitosAnimaisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALSilva F Inflammatory cell infiltration....pdfSilva F Inflammatory cell infiltration....pdfapplication/pdf468424https://www.arca.fiocruz.br/bitstream/icict/3239/1/Silva%20F%20Inflammatory%20cell%20infiltration....pdf27dce6a49eb7b55d0e2786e519a3cff9MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/3239/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTSilva F Inflammatory cell infiltration....pdf.txtSilva F Inflammatory cell infiltration....pdf.txtExtracted texttext/plain21192https://www.arca.fiocruz.br/bitstream/icict/3239/5/Silva%20F%20Inflammatory%20cell%20infiltration....pdf.txta0de5a41c5cc8f03993a1555a50866e5MD55THUMBNAILSilva F Inflammatory cell infiltration....pdf.jpgSilva F Inflammatory cell infiltration....pdf.jpgGenerated Thumbnailimage/jpeg2126https://www.arca.fiocruz.br/bitstream/icict/3239/4/Silva%20F%20Inflammatory%20cell%20infiltration....pdf.jpg42126f9843c6e6a3ec80f1a2cfa4ba00MD54icict/32392023-03-15 14:33:56.838oai:www.arca.fiocruz.br:icict/3239Tk9OLUVYQ0xVU0lWRSBESVNUUklCVVRJT04gTElDRU5TRQoKQnkgc2lnbmluZyBhbmQgc3VibWl0dGluZyB0aGlzIGxpY2Vuc2UsIHlvdSAodGhlIGF1dGhvcihzKSBvciBjb3B5cmlnaHQKb3duZXIpIGdyYW50cyB0byBEU3BhY2UgVW5pdmVyc2l0eSAoRFNVKSB0aGUgbm9uLWV4Y2x1c2l2ZSByaWdodCB0byByZXByb2R1Y2UsCnRyYW5zbGF0ZSAoYXMgZGVmaW5lZCBiZWxvdyksIGFuZC9vciBkaXN0cmlidXRlIHlvdXIgc3VibWlzc2lvbiAoaW5jbHVkaW5nCnRoZSBhYnN0cmFjdCkgd29ybGR3aWRlIGluIHByaW50IGFuZCBlbGVjdHJvbmljIGZvcm1hdCBhbmQgaW4gYW55IG1lZGl1bSwKaW5jbHVkaW5nIGJ1dCBub3QgbGltaXRlZCB0byBhdWRpbyBvciB2aWRlby4KCllvdSBhZ3JlZSB0aGF0IERTVSBtYXksIHdpdGhvdXQgY2hhbmdpbmcgdGhlIGNvbnRlbnQsIHRyYW5zbGF0ZSB0aGUKc3VibWlzc2lvbiB0byBhbnkgbWVkaXVtIG9yIGZvcm1hdCBmb3IgdGhlIHB1cnBvc2Ugb2YgcHJlc2VydmF0aW9uLgoKWW91IGFsc28gYWdyZWUgdGhhdCBEU1UgbWF5IGtlZXAgbW9yZSB0aGFuIG9uZSBjb3B5IG9mIHRoaXMgc3VibWlzc2lvbiBmb3IKcHVycG9zZXMgb2Ygc2VjdXJpdHksIGJhY2stdXAgYW5kIHByZXNlcnZhdGlvbi4KCllvdSByZXByZXNlbnQgdGhhdCB0aGUgc3VibWlzc2lvbiBpcyB5b3VyIG9yaWdpbmFsIHdvcmssIGFuZCB0aGF0IHlvdSBoYXZlCnRoZSByaWdodCB0byBncmFudCB0aGUgcmlnaHRzIGNvbnRhaW5lZCBpbiB0aGlzIGxpY2Vuc2UuIFlvdSBhbHNvIHJlcHJlc2VudAp0aGF0IHlvdXIgc3VibWlzc2lvbiBkb2VzIG5vdCwgdG8gdGhlIGJlc3Qgb2YgeW91ciBrbm93bGVkZ2UsIGluZnJpbmdlIHVwb24KYW55b25lJ3MgY29weXJpZ2h0LgoKSWYgdGhlIHN1Ym1pc3Npb24gY29udGFpbnMgbWF0ZXJpYWwgZm9yIHdoaWNoIHlvdSBkbyBub3QgaG9sZCBjb3B5cmlnaHQsCnlvdSByZXByZXNlbnQgdGhhdCB5b3UgaGF2ZSBvYnRhaW5lZCB0aGUgdW5yZXN0cmljdGVkIHBlcm1pc3Npb24gb2YgdGhlCmNvcHlyaWdodCBvd25lciB0byBncmFudCBEU1UgdGhlIHJpZ2h0cyByZXF1aXJlZCBieSB0aGlzIGxpY2Vuc2UsIGFuZCB0aGF0CnN1Y2ggdGhpcmQtcGFydHkgb3duZWQgbWF0ZXJpYWwgaXMgY2xlYXJseSBpZGVudGlmaWVkIGFuZCBhY2tub3dsZWRnZWQKd2l0aGluIHRoZSB0ZXh0IG9yIGNvbnRlbnQgb2YgdGhlIHN1Ym1pc3Npb24uCgpJRiBUSEUgU1VCTUlTU0lPTiBJUyBCQVNFRCBVUE9OIFdPUksgVEhBVCBIQVMgQkVFTiBTUE9OU09SRUQgT1IgU1VQUE9SVEVECkJZIEFOIEFHRU5DWSBPUiBPUkdBTklaQVRJT04gT1RIRVIgVEhBTiBEU1UsIFlPVSBSRVBSRVNFTlQgVEhBVCBZT1UgSEFWRQpGVUxGSUxMRUQgQU5ZIFJJR0hUIE9GIFJFVklFVyBPUiBPVEhFUiBPQkxJR0FUSU9OUyBSRVFVSVJFRCBCWSBTVUNICkNPTlRSQUNUIE9SIEFHUkVFTUVOVC4KCkRTVSB3aWxsIGNsZWFybHkgaWRlbnRpZnkgeW91ciBuYW1lKHMpIGFzIHRoZSBhdXRob3Iocykgb3Igb3duZXIocykgb2YgdGhlCnN1Ym1pc3Npb24sIGFuZCB3aWxsIG5vdCBtYWtlIGFueSBhbHRlcmF0aW9uLCBvdGhlciB0aGFuIGFzIGFsbG93ZWQgYnkgdGhpcwpsaWNlbnNlLCB0byB5b3VyIHN1Ym1pc3Npb24uCg==Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:56Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Inflammatory cell infiltration and high antibody production in balb/c mice caused by natural exposure to Lutzomyia longipalpis bites |
| title |
Inflammatory cell infiltration and high antibody production in balb/c mice caused by natural exposure to Lutzomyia longipalpis bites |
| spellingShingle |
Inflammatory cell infiltration and high antibody production in balb/c mice caused by natural exposure to Lutzomyia longipalpis bites Silva, Francinaldo Anticorpos Mordeduras e Picadas de Insetos Macrófagos Camundongos Endogâmicos BALB C Psychodidae Saliva Linfócitos Animais |
| title_short |
Inflammatory cell infiltration and high antibody production in balb/c mice caused by natural exposure to Lutzomyia longipalpis bites |
| title_full |
Inflammatory cell infiltration and high antibody production in balb/c mice caused by natural exposure to Lutzomyia longipalpis bites |
| title_fullStr |
Inflammatory cell infiltration and high antibody production in balb/c mice caused by natural exposure to Lutzomyia longipalpis bites |
| title_full_unstemmed |
Inflammatory cell infiltration and high antibody production in balb/c mice caused by natural exposure to Lutzomyia longipalpis bites |
| title_sort |
Inflammatory cell infiltration and high antibody production in balb/c mice caused by natural exposure to Lutzomyia longipalpis bites |
| author |
Silva, Francinaldo |
| author_facet |
Silva, Francinaldo Gomes, Regis Bernardo Brandim Prates, Deboraci Brito Miranda, José Carlos Andrade, Bruno de Bezerril Barral Netto, Manoel Barral, Aldina Maria Prado |
| author_role |
author |
| author2 |
Gomes, Regis Bernardo Brandim Prates, Deboraci Brito Miranda, José Carlos Andrade, Bruno de Bezerril Barral Netto, Manoel Barral, Aldina Maria Prado |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Silva, Francinaldo Gomes, Regis Bernardo Brandim Prates, Deboraci Brito Miranda, José Carlos Andrade, Bruno de Bezerril Barral Netto, Manoel Barral, Aldina Maria Prado |
| dc.subject.decs.pt_BR.fl_str_mv |
Anticorpos Mordeduras e Picadas de Insetos Macrófagos Camundongos Endogâmicos BALB C Psychodidae Saliva Linfócitos Animais |
| topic |
Anticorpos Mordeduras e Picadas de Insetos Macrófagos Camundongos Endogâmicos BALB C Psychodidae Saliva Linfócitos Animais |
| description |
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brazil |
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2005 |
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2005 |
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2011-09-14T18:12:44Z |
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2011-09-14T18:12:44Z |
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info:eu-repo/semantics/publishedVersion |
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SILVA, F. et al. Inflammatory cell infiltration and high antibody production in BALB/c mice caused by natural exposure to Lutzomyia longipalpis bites. American Journal of Tropical Medicine and Hygiene, v.72, n.1, p.94-98, jan. 2005. |
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https://www.arca.fiocruz.br/handle/icict/3239 |
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0002-9637 |
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SILVA, F. et al. Inflammatory cell infiltration and high antibody production in BALB/c mice caused by natural exposure to Lutzomyia longipalpis bites. American Journal of Tropical Medicine and Hygiene, v.72, n.1, p.94-98, jan. 2005. 0002-9637 |
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