Prevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazil

Detalhes bibliográficos
Autor(a) principal: Oliveira, Luciana A.
Data de Publicação: 2002
Outros Autores: Martins, Regina M. B., Carneiro, Megmar A. S., Teles, Sheila A., Silva, Simonne A., Cardoso, Divina D. P., Lampe, Elisabeth, Yoshida, Clara F. T.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/35180
Resumo: Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.
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spelling Oliveira, Luciana A.Martins, Regina M. B.Carneiro, Megmar A. S.Teles, Sheila A.Silva, Simonne A.Cardoso, Divina D. P.Lampe, ElisabethYoshida, Clara F. T.2019-08-29T12:26:48Z2019-08-29T12:26:48Z2002OLIVEIRA, Luciana A. et al. Prevalence and Genotypes of GB Virus C/Hepatitis G Virus among Blood Donors in Central Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n. 7, p. 953-957, Oct. 2002.0074-0276https://www.arca.fiocruz.br/handle/icict/3518010.1590/s0074-027620020007000051678-8060engFundação Oswaldo Cruz. Instituto Oswaldo CruzVírus da Hepatite GVírus GB CDoadores de sangueGoiâniaBrasil CentralHepatitis G virusGB virus CBlood donorsGoiâniaCentral BrazilPrevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.A survey was conducted in a blood donor population of Central Brazil aiming to investigate the prevalence of GB virus C (GBV-C)/hepatitis G virus (HGV) infection and also to analyze the virus genotypes distribution. A total of 241 voluntary blood donors were interviewed at the State Blood Bank in Goiânia, State of Goiás, Brazil. Blood samples were collected and serum samples tested for GBV-C/HGV RNA by polymerase chain reaction. Genotypes were determined by restriction fragment length polymorphism (RFLP) analysis. Seventeen samples were GBV-C/HGV RNA-positive, resulting in a prevalence of 7.1% (95% CI: 4.2-11.1). A significant trend of GBV-C/HGV RNA positivity in relation to age was observed, with the highest prevalence in donors between 29-39 years old. Ten infected individuals were characterized by reporting parenteral (30%), sexual (18%), both (6%) and intrafamiliar (6%) transmission. However, 7 (40%) GBV-C/HGV RNA-positive donors did not mention any potential transmission route. RFLP analysis revealed the presence of genotypes 1 and 2 of GBV-C/HGV; more precisely, 10 (58.9%) samples were found belonging to the 2b subtype, 4 (23.5%) to the 2a subtype, and 3 (17.6%) to genotype 1. The present data indicate an intermediate endemicity of GBV-C/HGV infection among this blood donor population, and a predominant circulation of genotype 2 (subtype 2b) in Central Brazil.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/35180/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALElisabethLampe_ClaraYoshida_etal_IOC_2002.pdfElisabethLampe_ClaraYoshida_etal_IOC_2002.pdfapplication/pdf68595https://www.arca.fiocruz.br/bitstream/icict/35180/2/ElisabethLampe_ClaraYoshida_etal_IOC_2002.pdfee58a22cec4974774490c6baefcf07c9MD52TEXTElisabethLampe_ClaraYoshida_etal_IOC_2002.pdf.txtElisabethLampe_ClaraYoshida_etal_IOC_2002.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Prevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazil
title Prevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazil
spellingShingle Prevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazil
Oliveira, Luciana A.
Vírus da Hepatite G
Vírus GB C
Doadores de sangue
Goiânia
Brasil Central
Hepatitis G virus
GB virus C
Blood donors
Goiânia
Central Brazil
title_short Prevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazil
title_full Prevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazil
title_fullStr Prevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazil
title_full_unstemmed Prevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazil
title_sort Prevalence and genotypes of GB virus C/hepatitis G virus among blood donors in Central Brazil
author Oliveira, Luciana A.
author_facet Oliveira, Luciana A.
Martins, Regina M. B.
Carneiro, Megmar A. S.
Teles, Sheila A.
Silva, Simonne A.
Cardoso, Divina D. P.
Lampe, Elisabeth
Yoshida, Clara F. T.
author_role author
author2 Martins, Regina M. B.
Carneiro, Megmar A. S.
Teles, Sheila A.
Silva, Simonne A.
Cardoso, Divina D. P.
Lampe, Elisabeth
Yoshida, Clara F. T.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Luciana A.
Martins, Regina M. B.
Carneiro, Megmar A. S.
Teles, Sheila A.
Silva, Simonne A.
Cardoso, Divina D. P.
Lampe, Elisabeth
Yoshida, Clara F. T.
dc.subject.other.pt_BR.fl_str_mv Vírus da Hepatite G
Vírus GB C
Doadores de sangue
Goiânia
Brasil Central
topic Vírus da Hepatite G
Vírus GB C
Doadores de sangue
Goiânia
Brasil Central
Hepatitis G virus
GB virus C
Blood donors
Goiânia
Central Brazil
dc.subject.en.pt_BR.fl_str_mv Hepatitis G virus
GB virus C
Blood donors
Goiânia
Central Brazil
description Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.
publishDate 2002
dc.date.issued.fl_str_mv 2002
dc.date.accessioned.fl_str_mv 2019-08-29T12:26:48Z
dc.date.available.fl_str_mv 2019-08-29T12:26:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv OLIVEIRA, Luciana A. et al. Prevalence and Genotypes of GB Virus C/Hepatitis G Virus among Blood Donors in Central Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n. 7, p. 953-957, Oct. 2002.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/35180
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/s0074-02762002000700005
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv OLIVEIRA, Luciana A. et al. Prevalence and Genotypes of GB Virus C/Hepatitis G Virus among Blood Donors in Central Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n. 7, p. 953-957, Oct. 2002.
0074-0276
10.1590/s0074-02762002000700005
1678-8060
url https://www.arca.fiocruz.br/handle/icict/35180
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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