Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Luciano Corrêa
Data de Publicação: 2012
Outros Autores: Wanke, Bodo, Silva, Manuela da, Dias, Luciana Basili, Mello, Renato, Canavarros, Fernando Artur Pena Borges, Leite-Jr, Diniz Pereira, Hahn, Rosane Christine
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1007/s11046-011-9472-0
Texto Completo: https://www.arca.fiocruz.br/handle/icict/36627
Resumo: 2020-10-22
id CRUZ_7f5563622a053d3bfda82c6041752fdb
oai_identifier_str oai:www.arca.fiocruz.br:icict/36627
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Ribeiro, Luciano CorrêaWanke, BodoSilva, Manuela daDias, Luciana BasiliMello, RenatoCanavarros, Fernando Artur Pena BorgesLeite-Jr, Diniz PereiraHahn, Rosane Christine2019-10-22T13:02:26Z2019-10-22T13:02:26Z2012RIBEIRO, Luciano Corrêa et al. Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis. Mycopathologia, v. 173, p. 187-192, 2012.0301-486Xhttps://www.arca.fiocruz.br/handle/icict/3662710.1007/s11046-011-9472-01573-0832engSpringer VerlagMucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-10-22University of Mato Grosso. Faculty of Medicine. Mycology Laboratory. Cuiabá, MT, Brazil / Infectious and Tropical Diseases Centre of Mato Grosso. Cuiabá, MT, Brazil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Programa de Pós-Graduação em Vigilância Sanitária. Rio de Janeiro, RJ, Brasil.University of Mato Grosso. Faculty of Medicine. Mycology Laboratory. Cuiabá, MT, Brazil.Santa Rosa Hospital. Cuiabá, MT, Brazil.Santa Rosa Hospital. Cuiabá, MT, Brazil.Infectious and Tropical Diseases Centre of Mato Grosso. Cuiabá, MT, Brazil.University of Mato Grosso. Faculty of Medicine. Mycology Laboratory. Cuiabá, MT, Brazil.We identified the etiological agents responsible for two fatal cases of rhinocerebral mucormycosis with the classical risk factor for uncontrolled type II diabetes mellitus. Their initial symptoms did not point immediately to the suspicion of mucormycosis. Case 1, caused by Rhizopus microsporus var. oligosporus, was a 52-year-old man who presented with a painful pimple on his nose, which evolved with swelling, erythema, and a central pustule on his right hemiface suspected to be cellulitis. After 7 days of antibiotic treatment, the patient worsened with signs of sepsis and the lesion evolved to necrosis involving all his right face. Case 2, caused by Rhizopus microsporus var. rhizopodiformis, was a 57-year-old woman placed on continuous therapy with azathioprine and corticoids after a renal transplant due to chronic arterial hypertension and uncontrolled type II diabetes mellitus. Because she was suspected to have sepsis, the patient was treated with broadspectrum antibiotics and mechanical ventilation, yet she deteriorated. Because Candida spp. were isolated from urine and a BAL, she was treated with fluconazole for 10 days, then substituted by caspofungin. Two weeks later, she presented with exophthalmus of the left eye that was surrounded by a large inflammatory and necrotic area. Both patients were the diagnosed with mucormycosis via direct microscopy of necrotic material prior to their death.MucormycosisBrazilRhizopus microsporus var. oligosporusRhizopus microsporus var. rhizopodiformisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/36627/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Ribeiro_Luciano_etal_INI_2012.pdfve_Ribeiro_Luciano_etal_INI_2012.pdfapplication/pdf307881https://www.arca.fiocruz.br/bitstream/icict/36627/2/ve_Ribeiro_Luciano_etal_INI_2012.pdff0ae5d7bb2c6549001d1be54016699f8MD52TEXTve_Ribeiro_Luciano_etal_INI_2012.pdf.txtve_Ribeiro_Luciano_etal_INI_2012.pdf.txtExtracted texttext/plain22473https://www.arca.fiocruz.br/bitstream/icict/36627/3/ve_Ribeiro_Luciano_etal_INI_2012.pdf.txt182b00397fb0e1877895f49a056849d2MD53icict/366272021-03-24 16:32:38.079oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:38Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis
title Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis
spellingShingle Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis
Ribeiro, Luciano Corrêa
Mucormycosis
Brazil
Rhizopus microsporus var. oligosporus
Rhizopus microsporus var. rhizopodiformis
title_short Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis
title_full Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis
title_fullStr Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis
title_full_unstemmed Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis
title_sort Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis
author Ribeiro, Luciano Corrêa
author_facet Ribeiro, Luciano Corrêa
Wanke, Bodo
Silva, Manuela da
Dias, Luciana Basili
Mello, Renato
Canavarros, Fernando Artur Pena Borges
Leite-Jr, Diniz Pereira
Hahn, Rosane Christine
author_role author
author2 Wanke, Bodo
Silva, Manuela da
Dias, Luciana Basili
Mello, Renato
Canavarros, Fernando Artur Pena Borges
Leite-Jr, Diniz Pereira
Hahn, Rosane Christine
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ribeiro, Luciano Corrêa
Wanke, Bodo
Silva, Manuela da
Dias, Luciana Basili
Mello, Renato
Canavarros, Fernando Artur Pena Borges
Leite-Jr, Diniz Pereira
Hahn, Rosane Christine
dc.subject.en.pt_BR.fl_str_mv Mucormycosis
Brazil
Rhizopus microsporus var. oligosporus
Rhizopus microsporus var. rhizopodiformis
topic Mucormycosis
Brazil
Rhizopus microsporus var. oligosporus
Rhizopus microsporus var. rhizopodiformis
description 2020-10-22
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2019-10-22T13:02:26Z
dc.date.available.fl_str_mv 2019-10-22T13:02:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv RIBEIRO, Luciano Corrêa et al. Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis. Mycopathologia, v. 173, p. 187-192, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/36627
dc.identifier.issn.pt_BR.fl_str_mv 0301-486X
dc.identifier.doi.none.fl_str_mv 10.1007/s11046-011-9472-0
dc.identifier.eissn.none.fl_str_mv 1573-0832
identifier_str_mv RIBEIRO, Luciano Corrêa et al. Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis. Mycopathologia, v. 173, p. 187-192, 2012.
0301-486X
10.1007/s11046-011-9472-0
1573-0832
url https://www.arca.fiocruz.br/handle/icict/36627
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Verlag
publisher.none.fl_str_mv Springer Verlag
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/36627/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/36627/2/ve_Ribeiro_Luciano_etal_INI_2012.pdf
https://www.arca.fiocruz.br/bitstream/icict/36627/3/ve_Ribeiro_Luciano_etal_INI_2012.pdf.txt
bitstream.checksum.fl_str_mv 8a4605be74aa9ea9d79846c1fba20a33
f0ae5d7bb2c6549001d1be54016699f8
182b00397fb0e1877895f49a056849d2
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1822792145132584960

Registros relacionados