Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system

Detalhes bibliográficos
Autor(a) principal: Azevedo, Carine Machado
Data de Publicação: 2006
Outros Autores: Borges, Claudia Maria da Cunha, Andrade, Zilton de Araújo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/2753
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
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spelling Azevedo, Carine MachadoBorges, Claudia Maria da CunhaAndrade, Zilton de Araújo2011-07-13T18:06:51Z2011-07-13T18:06:51Z2006AZEVEDO, C. M.; BORGES, C. C.; ANDRADE, Z. A. Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system. Memórias do Instituto Oswaldo Cruz, v.101, supl.1, p.199-203, 2006.0074-0276https://www.arca.fiocruz.br/handle/icict/2753engMemórias do Instituto Oswaldo CruzHemócitosBiomphalaria glabrataSchistosoma mansoniAntígenosHemocytesBiomphalaria glabrataSchistosoma mansoniAntigensHemócitosSchistosoma mansoniAntígenosChanges induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense systeminfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, BrasilBiomphalaria glabrata can react through different pathways to Schistosoma mansoni miracidium penetration, according to the degree of resistance/susceptibility presented by different snail strains, which is a genetically determined character, resistance being the dominant feature. However, it has been observed that previous susceptible snail strain may change its reactive behavior along the course of infection, exhibiting later a pattern of cercarial shedding and histopatopathological picture compatible with high resistance. Such observation suggests the possibility of B. glabrata to develop a sort of adaptative immunity face a schistosome infection. To explore on this aspect, the present investigation looked for the behavior of S. mansoni infection in B. glabrata previously subjected to different means of artificial stimulation of its internal defense system. Snails previously inoculated with irradiated miracídia (Group I); treated with S. mansoni antigens (Group II) or with a non-related parasite antigen (Group III) were challenged with 20 viable S. mansoni miracidia, and later looked for cercarial shedding and histopathologic changes at different times from exposition. Nodules of hemocyte accumulations were found at the site of antigen injection. These nodules resembled solid granulomas, and were larger and more frequent in snails injected with S. mansoni products as compared to those injected with Capillaria hepatica. However, the presence of such granulomas did not avoid the S. mansoni challenge infection from developing in a similar way as that seen in controls. The data are indicative that hemocytes are able to proliferate locally when stimulated, such capacity also remaining localized, not being shared by the population of hemocytes located elsewhere within the snail body.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALAzevedo_Borges_Andrade.pdfAzevedo_Borges_Andrade.pdfapplication/pdf2020934https://www.arca.fiocruz.br/bitstream/icict/2753/1/Azevedo_Borges_Andrade.pdf9ade401bd583c7084a5ea10f1bc2acb1MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/2753/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTAzevedo_Borges_Andrade.pdf.txtAzevedo_Borges_Andrade.pdf.txtExtracted texttext/plain18048https://www.arca.fiocruz.br/bitstream/icict/2753/5/Azevedo_Borges_Andrade.pdf.txt0e9193c57ca4726658087c12df8abd84MD55THUMBNAILAzevedo_Borges_Andrade.pdf.jpgAzevedo_Borges_Andrade.pdf.jpgGenerated Thumbnailimage/jpeg2292https://www.arca.fiocruz.br/bitstream/icict/2753/4/Azevedo_Borges_Andrade.pdf.jpgcf282393a90bc71a40e1261541d2002aMD54icict/27532023-03-15 14:34:09.511oai:www.arca.fiocruz.br:icict/2753Tk9OLUVYQ0xVU0lWRSBESVNUUklCVVRJT04gTElDRU5TRQoKQnkgc2lnbmluZyBhbmQgc3VibWl0dGluZyB0aGlzIGxpY2Vuc2UsIHlvdSAodGhlIGF1dGhvcihzKSBvciBjb3B5cmlnaHQKb3duZXIpIGdyYW50cyB0byBEU3BhY2UgVW5pdmVyc2l0eSAoRFNVKSB0aGUgbm9uLWV4Y2x1c2l2ZSByaWdodCB0byByZXByb2R1Y2UsCnRyYW5zbGF0ZSAoYXMgZGVmaW5lZCBiZWxvdyksIGFuZC9vciBkaXN0cmlidXRlIHlvdXIgc3VibWlzc2lvbiAoaW5jbHVkaW5nCnRoZSBhYnN0cmFjdCkgd29ybGR3aWRlIGluIHByaW50IGFuZCBlbGVjdHJvbmljIGZvcm1hdCBhbmQgaW4gYW55IG1lZGl1bSwKaW5jbHVkaW5nIGJ1dCBub3QgbGltaXRlZCB0byBhdWRpbyBvciB2aWRlby4KCllvdSBhZ3JlZSB0aGF0IERTVSBtYXksIHdpdGhvdXQgY2hhbmdpbmcgdGhlIGNvbnRlbnQsIHRyYW5zbGF0ZSB0aGUKc3VibWlzc2lvbiB0byBhbnkgbWVkaXVtIG9yIGZvcm1hdCBmb3IgdGhlIHB1cnBvc2Ugb2YgcHJlc2VydmF0aW9uLgoKWW91IGFsc28gYWdyZWUgdGhhdCBEU1UgbWF5IGtlZXAgbW9yZSB0aGFuIG9uZSBjb3B5IG9mIHRoaXMgc3VibWlzc2lvbiBmb3IKcHVycG9zZXMgb2Ygc2VjdXJpdHksIGJhY2stdXAgYW5kIHByZXNlcnZhdGlvbi4KCllvdSByZXByZXNlbnQgdGhhdCB0aGUgc3VibWlzc2lvbiBpcyB5b3VyIG9yaWdpbmFsIHdvcmssIGFuZCB0aGF0IHlvdSBoYXZlCnRoZSByaWdodCB0byBncmFudCB0aGUgcmlnaHRzIGNvbnRhaW5lZCBpbiB0aGlzIGxpY2Vuc2UuIFlvdSBhbHNvIHJlcHJlc2VudAp0aGF0IHlvdXIgc3VibWlzc2lvbiBkb2VzIG5vdCwgdG8gdGhlIGJlc3Qgb2YgeW91ciBrbm93bGVkZ2UsIGluZnJpbmdlIHVwb24KYW55b25lJ3MgY29weXJpZ2h0LgoKSWYgdGhlIHN1Ym1pc3Npb24gY29udGFpbnMgbWF0ZXJpYWwgZm9yIHdoaWNoIHlvdSBkbyBub3QgaG9sZCBjb3B5cmlnaHQsCnlvdSByZXByZXNlbnQgdGhhdCB5b3UgaGF2ZSBvYnRhaW5lZCB0aGUgdW5yZXN0cmljdGVkIHBlcm1pc3Npb24gb2YgdGhlCmNvcHlyaWdodCBvd25lciB0byBncmFudCBEU1UgdGhlIHJpZ2h0cyByZXF1aXJlZCBieSB0aGlzIGxpY2Vuc2UsIGFuZCB0aGF0CnN1Y2ggdGhpcmQtcGFydHkgb3duZWQgbWF0ZXJpYWwgaXMgY2xlYXJseSBpZGVudGlmaWVkIGFuZCBhY2tub3dsZWRnZWQKd2l0aGluIHRoZSB0ZXh0IG9yIGNvbnRlbnQgb2YgdGhlIHN1Ym1pc3Npb24uCgpJRiBUSEUgU1VCTUlTU0lPTiBJUyBCQVNFRCBVUE9OIFdPUksgVEhBVCBIQVMgQkVFTiBTUE9OU09SRUQgT1IgU1VQUE9SVEVECkJZIEFOIEFHRU5DWSBPUiBPUkdBTklaQVRJT04gT1RIRVIgVEhBTiBEU1UsIFlPVSBSRVBSRVNFTlQgVEhBVCBZT1UgSEFWRQpGVUxGSUxMRUQgQU5ZIFJJR0hUIE9GIFJFVklFVyBPUiBPVEhFUiBPQkxJR0FUSU9OUyBSRVFVSVJFRCBCWSBTVUNICkNPTlRSQUNUIE9SIEFHUkVFTUVOVC4KCkRTVSB3aWxsIGNsZWFybHkgaWRlbnRpZnkgeW91ciBuYW1lKHMpIGFzIHRoZSBhdXRob3Iocykgb3Igb3duZXIocykgb2YgdGhlCnN1Ym1pc3Npb24sIGFuZCB3aWxsIG5vdCBtYWtlIGFueSBhbHRlcmF0aW9uLCBvdGhlciB0aGFuIGFzIGFsbG93ZWQgYnkgdGhpcwpsaWNlbnNlLCB0byB5b3VyIHN1Ym1pc3Npb24uCg==Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:34:09Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system
title Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system
spellingShingle Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system
Azevedo, Carine Machado
Hemócitos
Biomphalaria glabrata
Schistosoma mansoni
Antígenos
Hemocytes
Biomphalaria glabrata
Schistosoma mansoni
Antigens
Hemócitos
Schistosoma mansoni
Antígenos
title_short Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system
title_full Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system
title_fullStr Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system
title_full_unstemmed Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system
title_sort Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system
author Azevedo, Carine Machado
author_facet Azevedo, Carine Machado
Borges, Claudia Maria da Cunha
Andrade, Zilton de Araújo
author_role author
author2 Borges, Claudia Maria da Cunha
Andrade, Zilton de Araújo
author2_role author
author
dc.contributor.author.fl_str_mv Azevedo, Carine Machado
Borges, Claudia Maria da Cunha
Andrade, Zilton de Araújo
dc.subject.other.pt_BR.fl_str_mv Hemócitos
Biomphalaria glabrata
Schistosoma mansoni
Antígenos
topic Hemócitos
Biomphalaria glabrata
Schistosoma mansoni
Antígenos
Hemocytes
Biomphalaria glabrata
Schistosoma mansoni
Antigens
Hemócitos
Schistosoma mansoni
Antígenos
dc.subject.en.pt_BR.fl_str_mv Hemocytes
Biomphalaria glabrata
Schistosoma mansoni
Antigens
dc.subject.decs.pt_BR.fl_str_mv Hemócitos
Schistosoma mansoni
Antígenos
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
publishDate 2006
dc.date.issued.fl_str_mv 2006
dc.date.accessioned.fl_str_mv 2011-07-13T18:06:51Z
dc.date.available.fl_str_mv 2011-07-13T18:06:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv AZEVEDO, C. M.; BORGES, C. C.; ANDRADE, Z. A. Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system. Memórias do Instituto Oswaldo Cruz, v.101, supl.1, p.199-203, 2006.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/2753
dc.identifier.issn.none.fl_str_mv 0074-0276
identifier_str_mv AZEVEDO, C. M.; BORGES, C. C.; ANDRADE, Z. A. Changes induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system. Memórias do Instituto Oswaldo Cruz, v.101, supl.1, p.199-203, 2006.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/2753
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Memórias do Instituto Oswaldo Cruz
publisher.none.fl_str_mv Memórias do Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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