Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo de conferência |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/23557 |
Resumo: | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil |
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Morais, Isa Rita Brito deGuerreiro, Marcos Lázaro da SilvaPatriota, G. S. QSantos, Viviane CorrêaMacedo, Andrea MaraAndrade, Sonia Gumes2017-12-07T17:45:20Z2017-12-07T17:45:20Z2012MORAIS, I. R. B. et al. Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18 e CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012.https://www.arca.fiocruz.br/handle/icict/23557engSociedade Brasileira de Medicina TropicalTrypanosoma cruziQuimioterápicosDrogasCamundogosAnimaisTrypanosoma cruziChemotherapicDrugsMiceAnimalsBiological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not curedinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, BrasilUniversidade Federal de Minas Gerais. Departamento de Bioquimica e IMunologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Departamento de Bioquimica e IMunologia. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, BrasilIntroduction: Different strains and clones of Trypanosoma cruzi present different degrees of susceptibility to treatment with chemotherapic drugs. Several studies have been developed to evaluate the response to different drugs concerning the strains prototypes of Biodemes Types I, II and III according to the biological characterization. Results have shown that the strains prototypes of the Biodeme Type I (Y and Peruvian strains) disclosed a high susceptibility to treatment with Benznidazole and Nifurtimox; strains of the Biodeme Type II (prototype: the 21SF strain) showed a medium susceptibility; the strains of the Biodeme Type III (Colombian strain) were highly resistantinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/23557/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALChag13 Morais IRB Biological and molecular... SBMT 2012.pdfChag13 Morais IRB Biological and molecular... SBMT 2012.pdfapplication/pdf88238https://www.arca.fiocruz.br/bitstream/icict/23557/2/Chag13%20Morais%20IRB%20Biological%20and%20molecular...%20SBMT%202012.pdf5ac2b42b471cb65d3f686313c43373d3MD52TEXTChag13 Morais IRB Biological and molecular... SBMT 2012.pdf.txtChag13 Morais IRB Biological and molecular... SBMT 2012.pdf.txtExtracted texttext/plain3109https://www.arca.fiocruz.br/bitstream/icict/23557/3/Chag13%20Morais%20IRB%20Biological%20and%20molecular...%20SBMT%202012.pdf.txt5b310c4deb425c0fae8a6f72f0f1f26bMD53icict/235572019-06-26 11:18:28.336oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-06-26T14:18:28Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured |
title |
Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured |
spellingShingle |
Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured Morais, Isa Rita Brito de Trypanosoma cruzi Quimioterápicos Drogas Camundogos Animais Trypanosoma cruzi Chemotherapic Drugs Mice Animals |
title_short |
Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured |
title_full |
Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured |
title_fullStr |
Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured |
title_full_unstemmed |
Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured |
title_sort |
Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured |
author |
Morais, Isa Rita Brito de |
author_facet |
Morais, Isa Rita Brito de Guerreiro, Marcos Lázaro da Silva Patriota, G. S. Q Santos, Viviane Corrêa Macedo, Andrea Mara Andrade, Sonia Gumes |
author_role |
author |
author2 |
Guerreiro, Marcos Lázaro da Silva Patriota, G. S. Q Santos, Viviane Corrêa Macedo, Andrea Mara Andrade, Sonia Gumes |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Morais, Isa Rita Brito de Guerreiro, Marcos Lázaro da Silva Patriota, G. S. Q Santos, Viviane Corrêa Macedo, Andrea Mara Andrade, Sonia Gumes |
dc.subject.other.pt_BR.fl_str_mv |
Trypanosoma cruzi Quimioterápicos Drogas Camundogos Animais |
topic |
Trypanosoma cruzi Quimioterápicos Drogas Camundogos Animais Trypanosoma cruzi Chemotherapic Drugs Mice Animals |
dc.subject.en.pt_BR.fl_str_mv |
Trypanosoma cruzi Chemotherapic Drugs Mice Animals |
description |
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2017-12-07T17:45:20Z |
dc.date.available.fl_str_mv |
2017-12-07T17:45:20Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/conferenceObject |
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conferenceObject |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
MORAIS, I. R. B. et al. Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18 e CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/23557 |
identifier_str_mv |
MORAIS, I. R. B. et al. Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18 e CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012. |
url |
https://www.arca.fiocruz.br/handle/icict/23557 |
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eng |
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eng |
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Sociedade Brasileira de Medicina Tropical |
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Sociedade Brasileira de Medicina Tropical |
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