Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response

Detalhes bibliográficos
Autor(a) principal: Koopmans, Marion
Data de Publicação: 2019
Outros Autores: Lamballerie, Xavier de, Jaenisch, Thomas, ZIKAlliance Consortium
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32313
Resumo: ZIKAlliance Consortium - Patricia Brasil - Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento.
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spelling Koopmans, MarionLamballerie, Xavier deJaenisch, ThomasZIKAlliance Consortium2019-04-01T14:23:08Z2019-04-01T14:23:08Z2019KOOPMANS, Marion et al. Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response. Lancet Infectious Diseases, v. 19, p. 59-62, Feb. 2019.1473-3099https://www.arca.fiocruz.br/handle/icict/3231310.1016/S1473-3099(18)30497-31474-4457ZIKAlliance Consortium - Patricia Brasil - Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento.ZIKAlliance Consortium - Renata Rabello - Fundação Oswaldo Cruz. Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.2020-03-01Erasmus MC. Rotterdam, Netherlands.Aix-Marseille University. Unité des Virus Émergents. Marseille, France.Heidelberg University Hospital. Section Clinical Tropical Medicine. Department of Infectious Diseases. Heidelberg, Germany.Research is an important component of an effective response to the increasing frequency of widespread infectious disease outbreaks. In turn, the ability to do such studies relies on willingness of partners in different regions to collaborate and the capacity to mount a rapid research response. The EU-funded ZIKAlliance Consortium has initiated a multicountry epidemiological, clinical, and laboratory research agenda to determine the incidence, risk factors, and outcomes of Zika virus infection in pregnant women and their children. We reviewed the timeline of patient cohort initiation in relation to the Zika virus epidemic and mapped key events regarding funding, regulatory approvals, and site preparation during this timeline. We then assessed barriers and delays that the international research team experienced through a systematic telephone interview. We have identified three major bottlenecks in the implementation of a swift response: the absence of a timeline for the funding process, delays in regulatory and ethical approval, and the challenging logistics of laboratory support, including diagnostics. These bottlenecks illustrate the clear and urgent need for implementing a strong and permanent global emerging infectious diseases research capacity that has structured funding, enables long-term partnerships, and develops basic clinical and laboratorial research and a response infrastructure that is ready to deploy.engElsevierFamiliar barriers still unresolved: a perspective on the Zika virus outbreak research responseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleZika virusPregnant womenResearch responseinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response
title Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response
spellingShingle Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response
Koopmans, Marion
Zika virus
Pregnant women
Research response
title_short Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response
title_full Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response
title_fullStr Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response
title_full_unstemmed Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response
title_sort Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response
author Koopmans, Marion
author_facet Koopmans, Marion
Lamballerie, Xavier de
Jaenisch, Thomas
ZIKAlliance Consortium
author_role author
author2 Lamballerie, Xavier de
Jaenisch, Thomas
ZIKAlliance Consortium
author2_role author
author
author
dc.contributor.author.fl_str_mv Koopmans, Marion
Lamballerie, Xavier de
Jaenisch, Thomas
ZIKAlliance Consortium
dc.subject.en.pt_BR.fl_str_mv Zika virus
Pregnant women
Research response
topic Zika virus
Pregnant women
Research response
description ZIKAlliance Consortium - Patricia Brasil - Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-04-01T14:23:08Z
dc.date.available.fl_str_mv 2019-04-01T14:23:08Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv KOOPMANS, Marion et al. Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response. Lancet Infectious Diseases, v. 19, p. 59-62, Feb. 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32313
dc.identifier.issn.pt_BR.fl_str_mv 1473-3099
dc.identifier.doi.none.fl_str_mv 10.1016/S1473-3099(18)30497-3
dc.identifier.eissn.none.fl_str_mv 1474-4457
identifier_str_mv KOOPMANS, Marion et al. Familiar barriers still unresolved: a perspective on the Zika virus outbreak research response. Lancet Infectious Diseases, v. 19, p. 59-62, Feb. 2019.
1473-3099
10.1016/S1473-3099(18)30497-3
1474-4457
url https://www.arca.fiocruz.br/handle/icict/32313
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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