Multicentric lymphoma in buffaloes in the Amazon region, Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2016 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/25500 |
Resumo: | Damasceno, Karine Araújo. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
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Oliveira, Cairo Henrique Sousa deBarbosa Neto, José DiomedesDamasceno, Karine AraujoCassali, Geovanni DantasOliveira, Carlos Magno ChavesLeite, Rômulo CeerqueiraReis, Jenner Karlisson Pimenta dos2018-03-26T19:22:35Z2018-03-26T19:22:35Z2016OLIVEIRA, C. H. S. et al. Multicentric lymphoma in buffaloes in the Amazon region, Brazil. BMC Veterinary Research, v. 12, p. 238, 2016.1746-6148https://www.arca.fiocruz.br/handle/icict/2550010.1186/s12917-016-0845-yDamasceno, Karine Araújo. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.Instituto Nacional de Ciência e Tecnologia - Pecuária (INCT-Pecuária), the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG). JKPR, RCL and JDB received fellowships from CNPq.Universidade Federal de Minas Gerais. Escola de Veterinária.Laboratório de Retroviroses. Departamento de Medicina Veterinária Preventiva. Belo Horizonte, MG, Brasil / Universidade Federal de Goiás. Escola de Veterinária e Zootecnia. Setor de Medicina Veterinária Preventiva. Goiânia, GO, Brasil.Universidade Federal do Pará. Instituto de Medicina Veterinária. Hospital Veterinário de Grandes Animais. Castanhal, PA, BrasilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Laboratório de Patologia Comparada. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Laboratório de Patologia Comparada. Belo Horizonte, MG, Brasil.Universidade Federal do Pará. Instituto de Medicina Veterinária. Hospital Veterinário de Grandes Animais. Castanhal, PA, Brasil.Universidade Federal de Minas Gerais. Escola de Veterinária.Laboratório de Retroviroses. Departamento de Medicina Veterinária Preventiva. Belo Horizonte, MG, Brasil / Universidade Federal de Goiás. Escola de Veterinária e Zootecnia. Setor de Medicina Veterinária Preventiva. Goiânia, GO, Brasil / Universidade Federal do Pará. Instituto de Medicina Veterinária. Hospital Veterinário de Grandes Animais. Castanhal, PA, Brasil.Universidade Federal de Minas Gerais. Escola de Veterinária.Laboratório de Retroviroses. Departamento de Medicina Veterinária Preventiva. Belo Horizonte, MG, Brasil / Universidade Federal de Goiás. Escola de Veterinária e Zootecnia. Setor de Medicina Veterinária Preventiva. Goiânia, GO, Brasil.The presence of lymphoma in buffaloes was first reported in India in the 1960s. The disease is similar to Enzootic Bovine Leucosis (EBL) caused by Bovine leukemia virus (BLV) in cattle; however, according to our results and those of other studies, the etiology of these lymphomas in buffalo do not appear to be associated with BLV. The objectives of this study are to describe four cases of the disease in buffaloes belonging to the same herd in the Amazon region of Brazil and to perform a clinical-anatomopathological, immunohistochemical, and etiological study of the lymphomas. Results: Over a period of ten years, four buffaloes were observed presenting progressive weight loss, swelling of peripheral lymph nodes, and nodules in the subcutaneous tissue. Upon necropsy, whitish-colored tumor masses were observed in the form of nodules in the subcutaneous tissue, along with miliary nodules on the serosal surfaces of abdominal and thoracic organs and tumors in lymph nodes and other organs. Neoplastic lymphocyte proliferation was observed through histopathology. An immunohistochemical study revealed that the neoplasias were formed by proliferation of predominantly B lymphocytes. The presence of BLV genome was not detected in the lymphomas when using the real-time PCR technique, nor was it detected through immunohistochemical staining using monoclonal antibodies against two viral proteins. Bovine herpesvirus 6 was not detected in the tumors. However, Bovine immunodeficiency virus (BIV) was detected in samples of lymphoma and in the lymph nodes and kidneys of one of the animals. Conclusions: The occurrence of lymphoma in buffaloes is reported for the first time in Brazil and is characterized by B-cell multicentric lymphoma. The etiology of the disease does not appear to be associated with BLV; however, the detection of BIV in samples of lymphoma from one sick animal deserves further study, considering the oncogenic potential of this virus.engBioMed CentralLinfomaBúfaloBIVBLVBoHV-6BrasilLymphomaBuffaloBIVBLVBoHV-6BrazilMulticentric lymphoma in buffaloes in the Amazon region, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/25500/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALOliveira CH Multicentric lymphoma in buffaloes....pdfOliveira CH Multicentric lymphoma in 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| dc.title.pt_BR.fl_str_mv |
Multicentric lymphoma in buffaloes in the Amazon region, Brazil |
| title |
Multicentric lymphoma in buffaloes in the Amazon region, Brazil |
| spellingShingle |
Multicentric lymphoma in buffaloes in the Amazon region, Brazil Oliveira, Cairo Henrique Sousa de Linfoma Búfalo BIV BLV BoHV-6 Brasil Lymphoma Buffalo BIV BLV BoHV-6 Brazil |
| title_short |
Multicentric lymphoma in buffaloes in the Amazon region, Brazil |
| title_full |
Multicentric lymphoma in buffaloes in the Amazon region, Brazil |
| title_fullStr |
Multicentric lymphoma in buffaloes in the Amazon region, Brazil |
| title_full_unstemmed |
Multicentric lymphoma in buffaloes in the Amazon region, Brazil |
| title_sort |
Multicentric lymphoma in buffaloes in the Amazon region, Brazil |
| author |
Oliveira, Cairo Henrique Sousa de |
| author_facet |
Oliveira, Cairo Henrique Sousa de Barbosa Neto, José Diomedes Damasceno, Karine Araujo Cassali, Geovanni Dantas Oliveira, Carlos Magno Chaves Leite, Rômulo Ceerqueira Reis, Jenner Karlisson Pimenta dos |
| author_role |
author |
| author2 |
Barbosa Neto, José Diomedes Damasceno, Karine Araujo Cassali, Geovanni Dantas Oliveira, Carlos Magno Chaves Leite, Rômulo Ceerqueira Reis, Jenner Karlisson Pimenta dos |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Oliveira, Cairo Henrique Sousa de Barbosa Neto, José Diomedes Damasceno, Karine Araujo Cassali, Geovanni Dantas Oliveira, Carlos Magno Chaves Leite, Rômulo Ceerqueira Reis, Jenner Karlisson Pimenta dos |
| dc.subject.other.pt_BR.fl_str_mv |
Linfoma Búfalo BIV BLV BoHV-6 Brasil |
| topic |
Linfoma Búfalo BIV BLV BoHV-6 Brasil Lymphoma Buffalo BIV BLV BoHV-6 Brazil |
| dc.subject.en.pt_BR.fl_str_mv |
Lymphoma Buffalo BIV BLV BoHV-6 Brazil |
| description |
Damasceno, Karine Araújo. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
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2016 |
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2016 |
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2018-03-26T19:22:35Z |
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2018-03-26T19:22:35Z |
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OLIVEIRA, C. H. S. et al. Multicentric lymphoma in buffaloes in the Amazon region, Brazil. BMC Veterinary Research, v. 12, p. 238, 2016. |
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https://www.arca.fiocruz.br/handle/icict/25500 |
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1746-6148 |
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10.1186/s12917-016-0845-y |
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OLIVEIRA, C. H. S. et al. Multicentric lymphoma in buffaloes in the Amazon region, Brazil. BMC Veterinary Research, v. 12, p. 238, 2016. 1746-6148 10.1186/s12917-016-0845-y |
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