Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups

Detalhes bibliográficos
Autor(a) principal: Costa, Giselle Calasans de Souza
Data de Publicação: 2009
Outros Autores: Alcantara, Luiz Carlos Júnior, Azevedo, Rochele, Muricy, Gabriel, Kashima, Simone Haddad, Covas, Dimas Tadeu, Castro Filho, Bernardo Galvão, Gadelha, Sandra Rocha
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/1897
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador,Bahia, Brasil
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spelling Costa, Giselle Calasans de SouzaAlcantara, Luiz Carlos JúniorAzevedo, RocheleMuricy, GabrielKashima, Simone HaddadCovas, Dimas TadeuCastro Filho, Bernardo GalvãoGadelha, Sandra Rocha2011-04-13T02:37:24Z2011-04-13T02:37:24Z2009COSTA, G. C. S. et al. Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups. Molecular Biology Reports, v.37, n.1, p. 75-79, 2010.0301-4851https://www.arca.fiocruz.br/handle/icict/189710.1007/s11033-009-9528-0engFrequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groupsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador,Bahia, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador,Bahia, BrasilLaboratório de Biologia Molecular, Banco de Sangue Regional de Ribeirão Preto, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, São Paulo, BrasilLaboratório Avançado de Saúde Pública. Centro de Pesquisas Gonçalo Moniz - FIOCRUZ, Bahia, BrasilUniversidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Laboratório de Biologia Molecular. Banco de Sangue Regional de Ribeirão Preto. São Paulo, BrasilUniversidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Laboratório de Biologia Molecular. Banco de Sangue Regional de Ribeirão Preto. São Paulo, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador,Bahia, BrasilUniversidade Estadual de Santa Cruz, Campus Prof Soane Nazaré de Andrade, Ilheus, Bahia, BrazilGLUT is the major glucose transporter in mammalian cells. Single nucleotide polymorphisms (SNP) at GLUT1 promoter and regulatory regions have been associated to the risk of developing nephropathy in different type 1 and type 2 diabetic populations. It has been demonstrated that differences in allelic and genotypic frequencies of GLUT1 gene (SLC2A1) polymorphisms occur among different populations. Therefore, ethnic differences in distribution of GLUT1 gene polymorphisms may be an important factor in determining gene-disease association. In this study, we investigated the XbaIG > T and HaeIIIT > C polymorphisms in six different Brazilian populations: 102 individuals from Salvador population (Northern Brazil), 56 European descendants from Joinville (South Brazil), 85 Indians from Tiryió tribe (North Brazil) and 127 samples from Southern Brazil: 44 from European descendants, 42 from African descendants and 41 from Japanese descendants. Genotype frequencies from both sites did not differ significantly from those expected under the Hardy-Weinberg equilibrium. We verified that the allele frequencies of both polymorphisms were heterogeneous in these six Brazilian ethnic groups.GLUT1PolymorphismsBrazilian populationsDesoxirribonucleases de Sítio Específico do Tipo IIGrupos ÉtnicosTransportador de Glucose Tipo 1Polimorfismo de Um Único NucleotídeoHumanosFrequência do Geneinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALFrequency distribution of XbaIG.pdfFrequency distribution of XbaIG.pdfapplication/pdf200744https://www.arca.fiocruz.br/bitstream/icict/1897/1/Frequency%20distribution%20of%20XbaIG.pdfd10e19f97efdcad831a70621eeb1aeebMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/1897/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTFrequency distribution of XbaIG.pdf.txtFrequency distribution of XbaIG.pdf.txtExtracted texttext/plain21611https://www.arca.fiocruz.br/bitstream/icict/1897/5/Frequency%20distribution%20of%20XbaIG.pdf.txte049dca4a636f47973f0b0d3cf1b22baMD55THUMBNAILFrequency distribution of XbaIG.pdf.jpgFrequency distribution of XbaIG.pdf.jpgGenerated Thumbnailimage/jpeg2024https://www.arca.fiocruz.br/bitstream/icict/1897/4/Frequency%20distribution%20of%20XbaIG.pdf.jpg5ec69082f115cd7931f6b4c31e22f341MD54icict/18972023-03-15 14:33:19.195oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:19Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups
title Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups
spellingShingle Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups
Costa, Giselle Calasans de Souza
GLUT1
Polymorphisms
Brazilian populations
Desoxirribonucleases de Sítio Específico do Tipo II
Grupos Étnicos
Transportador de Glucose Tipo 1
Polimorfismo de Um Único Nucleotídeo
Humanos
Frequência do Gene
title_short Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups
title_full Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups
title_fullStr Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups
title_full_unstemmed Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups
title_sort Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups
author Costa, Giselle Calasans de Souza
author_facet Costa, Giselle Calasans de Souza
Alcantara, Luiz Carlos Júnior
Azevedo, Rochele
Muricy, Gabriel
Kashima, Simone Haddad
Covas, Dimas Tadeu
Castro Filho, Bernardo Galvão
Gadelha, Sandra Rocha
author_role author
author2 Alcantara, Luiz Carlos Júnior
Azevedo, Rochele
Muricy, Gabriel
Kashima, Simone Haddad
Covas, Dimas Tadeu
Castro Filho, Bernardo Galvão
Gadelha, Sandra Rocha
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Costa, Giselle Calasans de Souza
Alcantara, Luiz Carlos Júnior
Azevedo, Rochele
Muricy, Gabriel
Kashima, Simone Haddad
Covas, Dimas Tadeu
Castro Filho, Bernardo Galvão
Gadelha, Sandra Rocha
dc.subject.en.pt_BR.fl_str_mv GLUT1
Polymorphisms
Brazilian populations
topic GLUT1
Polymorphisms
Brazilian populations
Desoxirribonucleases de Sítio Específico do Tipo II
Grupos Étnicos
Transportador de Glucose Tipo 1
Polimorfismo de Um Único Nucleotídeo
Humanos
Frequência do Gene
dc.subject.decs.pt_BR.fl_str_mv Desoxirribonucleases de Sítio Específico do Tipo II
Grupos Étnicos
Transportador de Glucose Tipo 1
Polimorfismo de Um Único Nucleotídeo
Humanos
Frequência do Gene
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador,Bahia, Brasil
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2011-04-13T02:37:24Z
dc.date.available.fl_str_mv 2011-04-13T02:37:24Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv COSTA, G. C. S. et al. Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups. Molecular Biology Reports, v.37, n.1, p. 75-79, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/1897
dc.identifier.issn.none.fl_str_mv 0301-4851
dc.identifier.doi.none.fl_str_mv 10.1007/s11033-009-9528-0
identifier_str_mv COSTA, G. C. S. et al. Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups. Molecular Biology Reports, v.37, n.1, p. 75-79, 2010.
0301-4851
10.1007/s11033-009-9528-0
url https://www.arca.fiocruz.br/handle/icict/1897
dc.language.iso.fl_str_mv eng
language eng
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