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spelling Resende, Paola CristinaNaveca, Felipe G.LIns, Roberto D.Dezordi, Filipe ZimmerFerraz, Matheus V. F.Moreira, Emerson G.Coelho, Danilo F.Motta, Fernando CoutoFerraz, Matheus V. F.Moreira, Emerson G.Coêlho, Danilo F.Motta, Fernando CoutoPaixão, Anna Carolina DiasAppolinario, LucianaLopes, Renata SerranoMendonça, Ana Carolina da FonsecaRocha, Alice Sampaio Barreto daNascimento, ValdineteSouza, VictorSilva, GeorgeNascimento, FernandaLima Neto, Lidio Gonçalves LimaSilva, Fabiano Vieira daRiediger, IrinaDebur, Maria do CarmoLeite, Anderson BrandãoMAttos, TirzaCosta, Cristiano Fernandes daPereira, Felicidade MotaSantos, Cliomar Alves dosRovaris, Darcita BuergerFernandes, Sandra BianchiniAbbud, AdrianoSacchi, ClaudioKhouri, RicardoBernardes, André Felipe LealDelatorre, EdsonGräf, TiagoSiqueira, Marilda Agudo Mendonça Teixeira deBello, GonzaloWallau, Gabriel L.2022-03-20T15:10:17Z2022-03-20T15:10:17Z2021RESENDE, Paola Cristina et al. The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein. Virus Evolution, v. 7, n. 2, p. 1 - 11, 2021.2057-1577https://www.arca.fiocruz.br/handle/icict/5175610.1093/ve/veab069engOxford University Presshttps://www.arca.fiocruz.br/handle/icict/49135COVID-19SARS-CoV-2PandemiasFuga de anticorposTransmissão comunitáriaCOVID-19PandemicsAntibody escapeSARS-CoV-2Community transmissionThe ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike proteininfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Entomologia. Recife, PE, Brasil / Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Núcleo de Bioinformática. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia. Recife, PE, Brasil / Universidade Federal de Pernambuco. Departamento de Química Fundamental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia. Recife, PE, Brasil / Universidade Federal de Pernambuco. Departamento de Química Fundamental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia. Recife, PE, Brasil / Universidade Federal de Pernambuco. Departamento de Química Fundamental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, AM, Brasil.Laboratório Central de Saúde Pública do Estado do Maranhão. São Luis, MA, Brasil.Laboratório Central de Saúde Pública do Estado do Maranhão. São Luis, MA, Brasil.Fundação de Vigilância em Saúde do Amazonas. Colônia Santo Antônio. Manaus, AM, Brasil.Laboratório Central de Saúde Pública do Estado da Bahia. Salvador, BA, Brasil.Laboratório Central de Saúde Pública do Estado de Sergipe. Aracaju, SE, Brasil.Laboratório Central de Saúde Pública do Estado de Santa Catarina. Florianópolis, SC, Brasil.Laboratório Central de Saúde Pública do Estado de Santa Catarina. Florianópolis, SC, Brasil.Instituto Adolfo Lutz. São Paulo, SP, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Enfermidades Infecciosas Transmitidas por Vetores. Salvador, BA, Brasil.Laboratório Central de Saúde Pública do Estado de Minas Gerais. Belo Horizonte, MG, Brasil.Universidade Federal do Espírito Santo. Centro de Ciências Exatas, Naturais e da Saúde. Departamento de Biologia. Alegre, ES, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Plataforma de Vigilância Molecular. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Entomologia. Recife, PE, Brasil / Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Núcleo de Bionformática. Recife, PE, Brasil.Mutations at both the receptor-binding domain (RBD) and the amino (N)-terminal domain (NTD) of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike (S) glycoprotein can alter its antigenicity and promote immune escape. We identified that SARS-CoV-2 lineages circulating in Brazil with mutations of concern in the RBD independently acquired convergent deletions and insertions in the NTD of the S protein, which altered the NTD antigenic-supersite and other predicted epitopes at this region. Importantly, we detected the community transmission of different P.1 lineages bearing NTD indels Δ69-70 (which can impact several SARS-CoV-2 diagnostic protocols), Δ144 and ins214ANRN, and a new VOI N.10 derived from the B.1.1.33 lineage carrying three NTD deletions (Δ141– 144, Δ211, and Δ256–258). These findings support that the ongoing widespread transmission of SARS-CoV-2 in Brazil generates new viral lineages that might be more resistant to antibody neutralization than parental variants of concern.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/51756/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALRenataLopes_PaolaResende_etal_IOC_2021.pdfRenataLopes_PaolaResende_etal_IOC_2021.pdfapplication/pdf3599837https://www.arca.fiocruz.br/bitstream/icict/51756/2/RenataLopes_PaolaResende_etal_IOC_2021.pdf3f2bf37d1c7a8ce40841dfe51cd05214MD52icict/517562022-03-25 23:39:39.821oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-03-26T02:39:39Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.pt_BR.fl_str_mv The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein
title The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein
spellingShingle The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein
Resende, Paola Cristina
COVID-19
SARS-CoV-2
Pandemias
Fuga de anticorpos
Transmissão comunitária
COVID-19
Pandemics
Antibody escape
SARS-CoV-2
Community transmission
title_short The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein
title_full The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein
title_fullStr The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein
title_full_unstemmed The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein
title_sort The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein
author Resende, Paola Cristina
author_facet Resende, Paola Cristina
Naveca, Felipe G.
LIns, Roberto D.
Dezordi, Filipe Zimmer
Ferraz, Matheus V. F.
Moreira, Emerson G.
Coelho, Danilo F.
Motta, Fernando Couto
Coêlho, Danilo F.
Paixão, Anna Carolina Dias
Appolinario, Luciana
Lopes, Renata Serrano
Mendonça, Ana Carolina da Fonseca
Rocha, Alice Sampaio Barreto da
Nascimento, Valdinete
Souza, Victor
Silva, George
Nascimento, Fernanda
Lima Neto, Lidio Gonçalves Lima
Silva, Fabiano Vieira da
Riediger, Irina
Debur, Maria do Carmo
Leite, Anderson Brandão
MAttos, Tirza
Costa, Cristiano Fernandes da
Pereira, Felicidade Mota
Santos, Cliomar Alves dos
Rovaris, Darcita Buerger
Fernandes, Sandra Bianchini
Abbud, Adriano
Sacchi, Claudio
Khouri, Ricardo
Bernardes, André Felipe Leal
Delatorre, Edson
Gräf, Tiago
Siqueira, Marilda Agudo Mendonça Teixeira de
Bello, Gonzalo
Wallau, Gabriel L.
author_role author
author2 Naveca, Felipe G.
LIns, Roberto D.
Dezordi, Filipe Zimmer
Ferraz, Matheus V. F.
Moreira, Emerson G.
Coelho, Danilo F.
Motta, Fernando Couto
Coêlho, Danilo F.
Paixão, Anna Carolina Dias
Appolinario, Luciana
Lopes, Renata Serrano
Mendonça, Ana Carolina da Fonseca
Rocha, Alice Sampaio Barreto da
Nascimento, Valdinete
Souza, Victor
Silva, George
Nascimento, Fernanda
Lima Neto, Lidio Gonçalves Lima
Silva, Fabiano Vieira da
Riediger, Irina
Debur, Maria do Carmo
Leite, Anderson Brandão
MAttos, Tirza
Costa, Cristiano Fernandes da
Pereira, Felicidade Mota
Santos, Cliomar Alves dos
Rovaris, Darcita Buerger
Fernandes, Sandra Bianchini
Abbud, Adriano
Sacchi, Claudio
Khouri, Ricardo
Bernardes, André Felipe Leal
Delatorre, Edson
Gräf, Tiago
Siqueira, Marilda Agudo Mendonça Teixeira de
Bello, Gonzalo
Wallau, Gabriel L.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Resende, Paola Cristina
Naveca, Felipe G.
LIns, Roberto D.
Dezordi, Filipe Zimmer
Ferraz, Matheus V. F.
Moreira, Emerson G.
Coelho, Danilo F.
Motta, Fernando Couto
Ferraz, Matheus V. F.
Moreira, Emerson G.
Coêlho, Danilo F.
Motta, Fernando Couto
Paixão, Anna Carolina Dias
Appolinario, Luciana
Lopes, Renata Serrano
Mendonça, Ana Carolina da Fonseca
Rocha, Alice Sampaio Barreto da
Nascimento, Valdinete
Souza, Victor
Silva, George
Nascimento, Fernanda
Lima Neto, Lidio Gonçalves Lima
Silva, Fabiano Vieira da
Riediger, Irina
Debur, Maria do Carmo
Leite, Anderson Brandão
MAttos, Tirza
Costa, Cristiano Fernandes da
Pereira, Felicidade Mota
Santos, Cliomar Alves dos
Rovaris, Darcita Buerger
Fernandes, Sandra Bianchini
Abbud, Adriano
Sacchi, Claudio
Khouri, Ricardo
Bernardes, André Felipe Leal
Delatorre, Edson
Gräf, Tiago
Siqueira, Marilda Agudo Mendonça Teixeira de
Bello, Gonzalo
Wallau, Gabriel L.
dc.subject.other.pt_BR.fl_str_mv COVID-19
SARS-CoV-2
Pandemias
Fuga de anticorpos
Transmissão comunitária
topic COVID-19
SARS-CoV-2
Pandemias
Fuga de anticorpos
Transmissão comunitária
COVID-19
Pandemics
Antibody escape
SARS-CoV-2
Community transmission
dc.subject.en.pt_BR.fl_str_mv COVID-19
Pandemics
Antibody escape
SARS-CoV-2
Community transmission
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-03-20T15:10:17Z
dc.date.available.fl_str_mv 2022-03-20T15:10:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv RESENDE, Paola Cristina et al. The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein. Virus Evolution, v. 7, n. 2, p. 1 - 11, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/51756
dc.identifier.issn.pt_BR.fl_str_mv 2057-1577
dc.identifier.doi.none.fl_str_mv 10.1093/ve/veab069
identifier_str_mv RESENDE, Paola Cristina et al. The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein. Virus Evolution, v. 7, n. 2, p. 1 - 11, 2021.
2057-1577
10.1093/ve/veab069
url https://www.arca.fiocruz.br/handle/icict/51756
dc.language.iso.fl_str_mv eng
language eng
dc.relation.isversionof.pt_BR.fl_str_mv https://www.arca.fiocruz.br/handle/icict/49135
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/51756/1/license.txt
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