Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study

Detalhes bibliográficos
Autor(a) principal: Voieta, Izabela
Data de Publicação: 2010
Outros Autores: Queiroz, Leonardo C. de, Andrade, Luciene M., Silva, Luciana Cristina S., Fontes, Vitor F., Barbosa Junior, Aryon de Almeida, Resende, Vivian, Petroianu, Andy, Andrade, Zilton de Araújo, Antunes, Carlos Mauricio de Figueiredo, Lambertucci, José Roberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/6063
Resumo: Universidade Federal de Minas Gerais. Faculdade de Medicina. Infectologia e Medicina Tropical. Belo Horizonte, MG, Brasil
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spelling Voieta, IzabelaQueiroz, Leonardo C. deAndrade, Luciene M.Silva, Luciana Cristina S.Fontes, Vitor F.Barbosa Junior, Aryon de AlmeidaResende, VivianPetroianu, AndyAndrade, Zilton de AraújoAntunes, Carlos Mauricio de FigueiredoLambertucci, José Roberto2012-12-26T17:57:24Z2012-12-26T17:57:24Z2010VOIETA, I. et al. Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study. Memórias do Instituto Oswaldo Cruz, v. 105, n. 4, p. 414-421, july. 2010.0074-0276https://www.arca.fiocruz.br/handle/icict/6063engImaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Faculdade de Medicina. Infectologia e Medicina Tropical. Belo Horizonte, MG, BrasilHospital das Clínicas. Serviço de Radiologia. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Infectologia e Medicina Tropical. Belo Horizonte, MG, Brasil / Laboratórios Hermes Pardini. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Infectologia e Medicina Tropical. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Infectologia e Medicina Tropical. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilServiço de Cirurgia de Fígado e Vias Biliares. Belo Horizonte, MG, BrasilServiço de Cirurgia de Fígado e Vias Biliares. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Infectologia e Medicina Tropical. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Infectologia e Medicina Tropical. Belo Horizonte, MG, BrasilFew publications have compared ultrasound (US) to histology in diagnosing schistosomiasis-induced liver fibrosis (LF); none has used magnetic resonance (MR). The aim of this study was to evaluate schistosomal LF using these three methods. Fourteen patients with hepatosplenic schistosomiasis admitted to hospital for surgical treatment of variceal bleeding were investigated. They were submitted to upper digestive endoscopy, US, MR and wedge liver biopsy. The World Health Organization protocol for US in schistosomiasis was used. Hepatic fibrosis was classified as absent, slight, moderate or intense. Histology and MR confirmed Symmers’ fibrosis in all cases. US failed to detect it in one patient. Moderate agreement was found comparing US to MR; poor agreement was found when US or MR were compared to histology. Re-classifying LF as only slight or intense created moderate agreement between imaging techniques and histology. Histomorphometry did not separate slight from intense LF. Two patients with advanced hepatosplenic schistosomiasis presented slight LF. Our data suggest that the presence of the characteristic periportal fibrosis, diagnosed by US, MR or histology, associated with a sign of portal hypertension, defines the severity of the disease. We conclude that imaging techniques are reliable to define the presence of LF but fail in grading its intensity.SchistosomiasisUltrasoundMagnetic resonanceLiver fibrosisSymmers’ fibrosisSplenectomyPortal hypertensionCirrose HepáticaHepatopatias ParasitáriasEsquistossomose mansoniEsplenopatiasBiópsiaVarizes Esofágicas e GástricasCirrose HepáticaCirrose Hepática/patologiaCirrose Hepática/ultrassonografiaHepatopatias ParasitáriasHepatopatias Parasitárias/patologiaHepatopatias Parasitárias/ultrassonografiaEsquistossomose mansoniEsquistossomose mansoni/patologiaEsquistossomose mansoni/ultrassonografiaÍndice de Gravidade de DoençaEsplenectomiaEsplenopatiasEsplenopatias/patologiaEsplenopatias/ultrassonografiaAdultoFemininoHumanosMasculinoMeia-IdadeAdulto JovemEstudo Comparativoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALVoieta, Izabela. et al. Imaging tecniques and histology....pdfVoieta, Izabela. et al. Imaging tecniques and histology....pdfapplication/pdf1518907https://www.arca.fiocruz.br/bitstream/icict/6063/1/Voieta%2c%20Izabela.%20et%20al.%20Imaging%20tecniques%20and%20histology....pdfcb332049b0fadf22bd08640731ac46a9MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/6063/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTVoieta, Izabela. et al. Imaging tecniques and histology....pdf.txtVoieta, Izabela. et al. Imaging tecniques and histology....pdf.txtExtracted texttext/plain31376https://www.arca.fiocruz.br/bitstream/icict/6063/5/Voieta%2c%20Izabela.%20et%20al.%20Imaging%20tecniques%20and%20histology....pdf.txt05c58f34239d1886070916e4ac375ebaMD55THUMBNAILVoieta, Izabela. et al. Imaging tecniques and histology....pdf.jpgVoieta, Izabela. et al. 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dc.title.pt_BR.fl_str_mv Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study
title Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study
spellingShingle Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study
Voieta, Izabela
Schistosomiasis
Ultrasound
Magnetic resonance
Liver fibrosis
Symmers’ fibrosis
Splenectomy
Portal hypertension
Cirrose Hepática
Hepatopatias Parasitárias
Esquistossomose mansoni
Esplenopatias
Biópsia
Varizes Esofágicas e Gástricas
Cirrose Hepática
Cirrose Hepática/patologia
Cirrose Hepática/ultrassonografia
Hepatopatias Parasitárias
Hepatopatias Parasitárias/patologia
Hepatopatias Parasitárias/ultrassonografia
Esquistossomose mansoni
Esquistossomose mansoni/patologia
Esquistossomose mansoni/ultrassonografia
Índice de Gravidade de Doença
Esplenectomia
Esplenopatias
Esplenopatias/patologia
Esplenopatias/ultrassonografia
Adulto
Feminino
Humanos
Masculino
Meia-Idade
Adulto Jovem
Estudo Comparativo
title_short Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study
title_full Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study
title_fullStr Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study
title_full_unstemmed Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study
title_sort Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study
author Voieta, Izabela
author_facet Voieta, Izabela
Queiroz, Leonardo C. de
Andrade, Luciene M.
Silva, Luciana Cristina S.
Fontes, Vitor F.
Barbosa Junior, Aryon de Almeida
Resende, Vivian
Petroianu, Andy
Andrade, Zilton de Araújo
Antunes, Carlos Mauricio de Figueiredo
Lambertucci, José Roberto
author_role author
author2 Queiroz, Leonardo C. de
Andrade, Luciene M.
Silva, Luciana Cristina S.
Fontes, Vitor F.
Barbosa Junior, Aryon de Almeida
Resende, Vivian
Petroianu, Andy
Andrade, Zilton de Araújo
Antunes, Carlos Mauricio de Figueiredo
Lambertucci, José Roberto
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Voieta, Izabela
Queiroz, Leonardo C. de
Andrade, Luciene M.
Silva, Luciana Cristina S.
Fontes, Vitor F.
Barbosa Junior, Aryon de Almeida
Resende, Vivian
Petroianu, Andy
Andrade, Zilton de Araújo
Antunes, Carlos Mauricio de Figueiredo
Lambertucci, José Roberto
dc.subject.en.pt_BR.fl_str_mv Schistosomiasis
Ultrasound
Magnetic resonance
Liver fibrosis
Symmers’ fibrosis
Splenectomy
Portal hypertension
topic Schistosomiasis
Ultrasound
Magnetic resonance
Liver fibrosis
Symmers’ fibrosis
Splenectomy
Portal hypertension
Cirrose Hepática
Hepatopatias Parasitárias
Esquistossomose mansoni
Esplenopatias
Biópsia
Varizes Esofágicas e Gástricas
Cirrose Hepática
Cirrose Hepática/patologia
Cirrose Hepática/ultrassonografia
Hepatopatias Parasitárias
Hepatopatias Parasitárias/patologia
Hepatopatias Parasitárias/ultrassonografia
Esquistossomose mansoni
Esquistossomose mansoni/patologia
Esquistossomose mansoni/ultrassonografia
Índice de Gravidade de Doença
Esplenectomia
Esplenopatias
Esplenopatias/patologia
Esplenopatias/ultrassonografia
Adulto
Feminino
Humanos
Masculino
Meia-Idade
Adulto Jovem
Estudo Comparativo
dc.subject.decs.pt_BR.fl_str_mv Cirrose Hepática
Hepatopatias Parasitárias
Esquistossomose mansoni
Esplenopatias
Biópsia
Varizes Esofágicas e Gástricas
Cirrose Hepática
Cirrose Hepática/patologia
Cirrose Hepática/ultrassonografia
Hepatopatias Parasitárias
Hepatopatias Parasitárias/patologia
Hepatopatias Parasitárias/ultrassonografia
Esquistossomose mansoni
Esquistossomose mansoni/patologia
Esquistossomose mansoni/ultrassonografia
Índice de Gravidade de Doença
Esplenectomia
Esplenopatias
Esplenopatias/patologia
Esplenopatias/ultrassonografia
Adulto
Feminino
Humanos
Masculino
Meia-Idade
Adulto Jovem
Estudo Comparativo
description Universidade Federal de Minas Gerais. Faculdade de Medicina. Infectologia e Medicina Tropical. Belo Horizonte, MG, Brasil
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2012-12-26T17:57:24Z
dc.date.available.fl_str_mv 2012-12-26T17:57:24Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv VOIETA, I. et al. Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study. Memórias do Instituto Oswaldo Cruz, v. 105, n. 4, p. 414-421, july. 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/6063
dc.identifier.issn.none.fl_str_mv 0074-0276
identifier_str_mv VOIETA, I. et al. Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study. Memórias do Instituto Oswaldo Cruz, v. 105, n. 4, p. 414-421, july. 2010.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/6063
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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