Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/25905 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ, Brasil. |
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Gama, Bianca E.Carvalho, Guilhermina A. L. PereiraLutucuta Kosi, Florbela J. I.Oliveira, Natália K. Almeida deFortes, FilomenoRosenthal, Philip J.Rosário, Virgílio E. deDaniel-Ribeiro, Cláudio TadeuCruz, Maria de Fátima Ferreira da2018-04-17T15:37:54Z2018-04-17T15:37:54Z2011GAMA, Bianca E. et al. Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola. Malaria Journal, v.10:248, 5p, 2011.1475-2875https://www.arca.fiocruz.br/handle/icict/2590510.1186/1475-2875-10-248engBioMed CentralPlasmodium falciparumMarcadores molecularesantifolato resistênciaLuandaPlasmodium falciparumMolecular markersantifolate resistanceLuandaMolecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angolainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ, Brasil.Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal.Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal.Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal.Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ, Brasil. / Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ, Brasil. / Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal / National Institute of Public Health. Luanda, Angola.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ, Brasil. / Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal.Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal / National Institute of Public Health. Luanda, Angola.University of California San Francisco. San Francisco General Hospital. Department of Medicine. San Francisco, CA, USA.Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ, Brasil. / Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ, Brasil. / Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Centro de Malária e Doenças Tropicais. Health Progress and Investigation Network of the Portuguese-Speaking Countries Community. Lisboa, Portugal.Plasmodium falciparum malaria remains a leading health problem in Africa and its control is seriously challenged by drug resistance. Although resistance to the sulphadoxine-pyrimethamine (SP) is widespread, this combination remains an important component of malaria control programmes as intermittent preventive therapy (IPT) for pregnant women and children. In Angola, resistance patterns have been poorly characterized, and IPT has been employed for pregnant women since 2006. The aim of this study was to assess the prevalence of key antifolate resistance mediating polymorphisms in the pfdhfr and pfdhps genes in P. falciparum samples from Angola.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/25905/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALflorbela_kosi_etal_IOC_2011.pdfflorbela_kosi_etal_IOC_2011.pdfapplication/pdf241379https://www.arca.fiocruz.br/bitstream/icict/25905/2/florbela_kosi_etal_IOC_2011.pdf33ecfb0820b6bcd12f20f94b6ed85f4eMD52TEXTflorbela_kosi_etal_IOC_2011.pdf.txtflorbela_kosi_etal_IOC_2011.pdf.txtExtracted texttext/plain24778https://www.arca.fiocruz.br/bitstream/icict/25905/3/florbela_kosi_etal_IOC_2011.pdf.txt88b00421335b3c7f2f940eb12eb5e015MD53icict/259052018-12-28 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| dc.title.pt_BR.fl_str_mv |
Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola |
| title |
Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola |
| spellingShingle |
Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola Gama, Bianca E. Plasmodium falciparum Marcadores moleculares antifolato resistência Luanda Plasmodium falciparum Molecular markers antifolate resistance Luanda |
| title_short |
Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola |
| title_full |
Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola |
| title_fullStr |
Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola |
| title_full_unstemmed |
Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola |
| title_sort |
Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola |
| author |
Gama, Bianca E. |
| author_facet |
Gama, Bianca E. Carvalho, Guilhermina A. L. Pereira Lutucuta Kosi, Florbela J. I. Oliveira, Natália K. Almeida de Fortes, Filomeno Rosenthal, Philip J. Rosário, Virgílio E. de Daniel-Ribeiro, Cláudio Tadeu Cruz, Maria de Fátima Ferreira da |
| author_role |
author |
| author2 |
Carvalho, Guilhermina A. L. Pereira Lutucuta Kosi, Florbela J. I. Oliveira, Natália K. Almeida de Fortes, Filomeno Rosenthal, Philip J. Rosário, Virgílio E. de Daniel-Ribeiro, Cláudio Tadeu Cruz, Maria de Fátima Ferreira da |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Gama, Bianca E. Carvalho, Guilhermina A. L. Pereira Lutucuta Kosi, Florbela J. I. Oliveira, Natália K. Almeida de Fortes, Filomeno Rosenthal, Philip J. Rosário, Virgílio E. de Daniel-Ribeiro, Cláudio Tadeu Cruz, Maria de Fátima Ferreira da |
| dc.subject.other.pt_BR.fl_str_mv |
Plasmodium falciparum Marcadores moleculares antifolato resistência Luanda |
| topic |
Plasmodium falciparum Marcadores moleculares antifolato resistência Luanda Plasmodium falciparum Molecular markers antifolate resistance Luanda |
| dc.subject.en.pt_BR.fl_str_mv |
Plasmodium falciparum Molecular markers antifolate resistance Luanda |
| description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ, Brasil. |
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2011 |
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2011 |
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2018-04-17T15:37:54Z |
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2018-04-17T15:37:54Z |
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GAMA, Bianca E. et al. Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola. Malaria Journal, v.10:248, 5p, 2011. |
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https://www.arca.fiocruz.br/handle/icict/25905 |
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1475-2875 |
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10.1186/1475-2875-10-248 |
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GAMA, Bianca E. et al. Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola. Malaria Journal, v.10:248, 5p, 2011. 1475-2875 10.1186/1475-2875-10-248 |
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