Whole cells in enantioselective reduction of benzyl acetoacetate

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Joyce Benzaquem
Data de Publicação: 2014
Outros Autores: Ramos, Aline de Souza, Lopes, Raquel de Oliveira Silva, Silva, Gabriela Veloso Vieira da, Souza, Rodrigo Octavio Mendonça Alves de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/47469
Resumo: Universidade Federal do Rio de Janeiro. Instituto de Química. Grupo de Biocatálise e Síntese Orgânica. Rio de Janeiro RJ, Brasil.
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spelling Ribeiro, Joyce BenzaquemRamos, Aline de SouzaLopes, Raquel de Oliveira SilvaSilva, Gabriela Veloso Vieira daSouza, Rodrigo Octavio Mendonça Alves de2021-05-31T19:51:44Z2021-05-31T19:51:44Z2014RIBEIRO, Joyce Benzaquem et al. Whole cells in enantioselective reduction of benzyl acetoacetate. Brazilian Journal of Microbiology, v. 45, n. 3, p. 929-932, Sept. 2014.1678-4405https://www.arca.fiocruz.br/handle/icict/4746910.1590/S1517-83822014000300023porWhole cells in enantioselective reduction of benzyl acetoacetateinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro. Instituto de Química. Grupo de Biocatálise e Síntese Orgânica. Rio de Janeiro RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Química. Grupo de Biocatálise e Síntese Orgânica. Rio de Janeiro RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Química. Grupo de Biocatálise e Síntese Orgânica. Rio de Janeiro RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Química. Grupo de Biocatálise e Síntese Orgânica. Rio de Janeiro RJ, Brasil.The β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction.BiotransformationChiral Reductionβ-KetoesterKluyveromyces MarxianusImmobilizationinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83093https://www.arca.fiocruz.br/bitstream/icict/47469/1/license.txt34529d73b0c3f33b39c969c511d590fbMD51ORIGINAL23.pdf23.pdfapplication/pdf583101https://www.arca.fiocruz.br/bitstream/icict/47469/2/23.pdfda9d79d19af762f9d099ec74de08e421MD52TEXT23.pdf.txt23.pdf.txtExtracted texttext/plain15939https://www.arca.fiocruz.br/bitstream/icict/47469/3/23.pdf.txt9377c310f27aa341ce09e355afd79bccMD53icict/474692021-06-09 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dc.title.pt_BR.fl_str_mv Whole cells in enantioselective reduction of benzyl acetoacetate
title Whole cells in enantioselective reduction of benzyl acetoacetate
spellingShingle Whole cells in enantioselective reduction of benzyl acetoacetate
Ribeiro, Joyce Benzaquem
Biotransformation
Chiral Reduction
β-Ketoester
Kluyveromyces Marxianus
Immobilization
title_short Whole cells in enantioselective reduction of benzyl acetoacetate
title_full Whole cells in enantioselective reduction of benzyl acetoacetate
title_fullStr Whole cells in enantioselective reduction of benzyl acetoacetate
title_full_unstemmed Whole cells in enantioselective reduction of benzyl acetoacetate
title_sort Whole cells in enantioselective reduction of benzyl acetoacetate
author Ribeiro, Joyce Benzaquem
author_facet Ribeiro, Joyce Benzaquem
Ramos, Aline de Souza
Lopes, Raquel de Oliveira Silva
Silva, Gabriela Veloso Vieira da
Souza, Rodrigo Octavio Mendonça Alves de
author_role author
author2 Ramos, Aline de Souza
Lopes, Raquel de Oliveira Silva
Silva, Gabriela Veloso Vieira da
Souza, Rodrigo Octavio Mendonça Alves de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Ribeiro, Joyce Benzaquem
Ramos, Aline de Souza
Lopes, Raquel de Oliveira Silva
Silva, Gabriela Veloso Vieira da
Souza, Rodrigo Octavio Mendonça Alves de
dc.subject.en.pt_BR.fl_str_mv Biotransformation
Chiral Reduction
β-Ketoester
Kluyveromyces Marxianus
Immobilization
topic Biotransformation
Chiral Reduction
β-Ketoester
Kluyveromyces Marxianus
Immobilization
description Universidade Federal do Rio de Janeiro. Instituto de Química. Grupo de Biocatálise e Síntese Orgânica. Rio de Janeiro RJ, Brasil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2021-05-31T19:51:44Z
dc.date.available.fl_str_mv 2021-05-31T19:51:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv RIBEIRO, Joyce Benzaquem et al. Whole cells in enantioselective reduction of benzyl acetoacetate. Brazilian Journal of Microbiology, v. 45, n. 3, p. 929-932, Sept. 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/47469
dc.identifier.issn.pt_BR.fl_str_mv 1678-4405
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/S1517-83822014000300023
identifier_str_mv RIBEIRO, Joyce Benzaquem et al. Whole cells in enantioselective reduction of benzyl acetoacetate. Brazilian Journal of Microbiology, v. 45, n. 3, p. 929-932, Sept. 2014.
1678-4405
10.1590/S1517-83822014000300023
url https://www.arca.fiocruz.br/handle/icict/47469
dc.language.iso.fl_str_mv por
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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