Whole cells in enantioselective reduction of benzyl acetoacetate
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Microbiology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300023 |
Resumo: | The β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction. |
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Brazilian Journal of Microbiology |
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Whole cells in enantioselective reduction of benzyl acetoacetatebiotransformationchiral reductionβ-ketoesterKluyveromyces marxianusimmobilizationThe β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction.Sociedade Brasileira de Microbiologia2014-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300023Brazilian Journal of Microbiology v.45 n.3 2014reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1590/S1517-83822014000300023info:eu-repo/semantics/openAccessRibeiro,Joyce BenzaquemRamos,Aline de SouzaLopes,Raquel de OliveiraSilva,Gabriela Veloso Vieira daSouza,Rodrigo Octavio Mendonça Alves deeng2014-11-04T00:00:00Zoai:scielo:S1517-83822014000300023Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2014-11-04T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false |
dc.title.none.fl_str_mv |
Whole cells in enantioselective reduction of benzyl acetoacetate |
title |
Whole cells in enantioselective reduction of benzyl acetoacetate |
spellingShingle |
Whole cells in enantioselective reduction of benzyl acetoacetate Ribeiro,Joyce Benzaquem biotransformation chiral reduction β-ketoester Kluyveromyces marxianus immobilization |
title_short |
Whole cells in enantioselective reduction of benzyl acetoacetate |
title_full |
Whole cells in enantioselective reduction of benzyl acetoacetate |
title_fullStr |
Whole cells in enantioselective reduction of benzyl acetoacetate |
title_full_unstemmed |
Whole cells in enantioselective reduction of benzyl acetoacetate |
title_sort |
Whole cells in enantioselective reduction of benzyl acetoacetate |
author |
Ribeiro,Joyce Benzaquem |
author_facet |
Ribeiro,Joyce Benzaquem Ramos,Aline de Souza Lopes,Raquel de Oliveira Silva,Gabriela Veloso Vieira da Souza,Rodrigo Octavio Mendonça Alves de |
author_role |
author |
author2 |
Ramos,Aline de Souza Lopes,Raquel de Oliveira Silva,Gabriela Veloso Vieira da Souza,Rodrigo Octavio Mendonça Alves de |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ribeiro,Joyce Benzaquem Ramos,Aline de Souza Lopes,Raquel de Oliveira Silva,Gabriela Veloso Vieira da Souza,Rodrigo Octavio Mendonça Alves de |
dc.subject.por.fl_str_mv |
biotransformation chiral reduction β-ketoester Kluyveromyces marxianus immobilization |
topic |
biotransformation chiral reduction β-ketoester Kluyveromyces marxianus immobilization |
description |
The β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300023 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300023 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1517-83822014000300023 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Microbiologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Microbiologia |
dc.source.none.fl_str_mv |
Brazilian Journal of Microbiology v.45 n.3 2014 reponame:Brazilian Journal of Microbiology instname:Sociedade Brasileira de Microbiologia (SBM) instacron:SBM |
instname_str |
Sociedade Brasileira de Microbiologia (SBM) |
instacron_str |
SBM |
institution |
SBM |
reponame_str |
Brazilian Journal of Microbiology |
collection |
Brazilian Journal of Microbiology |
repository.name.fl_str_mv |
Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM) |
repository.mail.fl_str_mv |
bjm@sbmicrobiologia.org.br||mbmartin@usp.br |
_version_ |
1752122206605803520 |