Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/56932 |
Resumo: | Background: The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding Plasmodium vivax infected NHPs adds even more concern. Methods: Both Free-living monkeys in forest fragments inside the urban area and captive monkeys from a local zoo had blood samples tested for Plasmodium species. Results: In this study, among the Neotropical monkeys tested, three (4.4%), one captive and two free-living, were found to be naturally infected by P. vivax. Conclusion: This important finding indicates that it is necessary to estimate the extent to which P. vivax NHP infection contributes to the maintenance of malaria transmission to humans. Therefore, the discussion on wildlife conservation and management must be incorporated into the malaria elimination agenda. |
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Chaves, Bárbara AparecidaAlvarenga, Denise Anete Madureira dePereira, Matheus de Oliveira CostaGordo, MarceloSilva, Emanuelle L DaCosta, Edson RodriguesMedeiros, Aline Souza de MenezesPedrosa, Igor José MartinsBrito, DanielaLima, Maurício TeixeiraMourão, Maria PaulaMonteiro, Wuelton MVasilakis, NikosBrito, Cristiana Ferreira Alves deMelo, Gisely CLacerda, Marcus V G2023-02-07T17:48:34Z2023-02-07T17:48:34Z2022CHAVES, Bárbara Aparecida et al. Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? Malar J., v. 21, n. 1, 343, 2022. doi: 10.1186/s12936-022-04349-6.1475-2875https://www.arca.fiocruz.br/handle/icict/56932engBioMed CentralIs zoonotic Plasmodium vivax malaria an obstacle for disease elimination?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBackground: The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding Plasmodium vivax infected NHPs adds even more concern. Methods: Both Free-living monkeys in forest fragments inside the urban area and captive monkeys from a local zoo had blood samples tested for Plasmodium species. Results: In this study, among the Neotropical monkeys tested, three (4.4%), one captive and two free-living, were found to be naturally infected by P. vivax. Conclusion: This important finding indicates that it is necessary to estimate the extent to which P. vivax NHP infection contributes to the maintenance of malaria transmission to humans. Therefore, the discussion on wildlife conservation and management must be incorporated into the malaria elimination agenda.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/do Estado do Amazonas. Manaus, AM, Brazil/Universidade Federal do Amazonas. Programa de Pós-Graduação em Ciências da Saúde. Manaus, AM, Brazil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de pesquisa em Biologia molecular e imunologia da Malária. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de pesquisa em Biologia molecular e imunologia da Malária. Belo Horizonte, MG, Brazil.Universidade Federal do Amazonas. Instituto de Ciências Biológicas. Laboratório de Biologia da Conservação. Projeto Sauim-de-Coleira. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil.Universidade Federal do Amazonas. Instituto de Ciências Biológicas. Laboratório de Biologia da Conservação. Projeto Sauim-de-Coleira. Manaus, AM, Brazil/Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil.Universidade Federal do Amazonas. Instituto de Ciências Biológicas. Laboratório de Biologia da Conservação. Projeto Sauim-de-Coleira. Manaus, AM, Brazil/Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/Universidade Federal do Amazonas. Programa de Pós-Graduação em Ciências da Saúde. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, BrazilFundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/Universidade do Estado do Amazonas. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/Universidade do Estado do Amazonas. Manaus, AM, Brazil.Department of Pathology. Center for Biodefense and Emerging Infectious Diseases. Center for Tropical Diseases. Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX, USA.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de pesquisa em Biologia molecular e imunologia da Malária. Belo Horizonte, MG, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/Universidade do Estado do Amazonas. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/Fundação Oswaldo Cruz. Instituto Leônidas & Maria Deane. Manaus, AM, Brazil.MalariaMalaria eliminationNon-human primatesPlasmodium vivaxZoonotic cycleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/56932/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALIs zoonotic Plasmodium vivax malaria an.pdfIs zoonotic Plasmodium vivax malaria an.pdfapplication/pdf1067647https://www.arca.fiocruz.br/bitstream/icict/56932/2/Is%20zoonotic%20Plasmodium%20vivax%20malaria%20an.pdf5048f3e28ac2b542e928e75a5dcff1adMD52icict/569322023-02-07 14:48:35.878oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-02-07T17:48:35Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.en_US.fl_str_mv |
Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
title |
Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
spellingShingle |
Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? Chaves, Bárbara Aparecida Malaria Malaria elimination Non-human primates Plasmodium vivax Zoonotic cycle |
title_short |
Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
title_full |
Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
title_fullStr |
Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
title_full_unstemmed |
Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
title_sort |
Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
author |
Chaves, Bárbara Aparecida |
author_facet |
Chaves, Bárbara Aparecida Alvarenga, Denise Anete Madureira de Pereira, Matheus de Oliveira Costa Gordo, Marcelo Silva, Emanuelle L Da Costa, Edson Rodrigues Medeiros, Aline Souza de Menezes Pedrosa, Igor José Martins Brito, Daniela Lima, Maurício Teixeira Mourão, Maria Paula Monteiro, Wuelton M Vasilakis, Nikos Brito, Cristiana Ferreira Alves de Melo, Gisely C Lacerda, Marcus V G |
author_role |
author |
author2 |
Alvarenga, Denise Anete Madureira de Pereira, Matheus de Oliveira Costa Gordo, Marcelo Silva, Emanuelle L Da Costa, Edson Rodrigues Medeiros, Aline Souza de Menezes Pedrosa, Igor José Martins Brito, Daniela Lima, Maurício Teixeira Mourão, Maria Paula Monteiro, Wuelton M Vasilakis, Nikos Brito, Cristiana Ferreira Alves de Melo, Gisely C Lacerda, Marcus V G |
author2_role |
author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Chaves, Bárbara Aparecida Alvarenga, Denise Anete Madureira de Pereira, Matheus de Oliveira Costa Gordo, Marcelo Silva, Emanuelle L Da Costa, Edson Rodrigues Medeiros, Aline Souza de Menezes Pedrosa, Igor José Martins Brito, Daniela Lima, Maurício Teixeira Mourão, Maria Paula Monteiro, Wuelton M Vasilakis, Nikos Brito, Cristiana Ferreira Alves de Melo, Gisely C Lacerda, Marcus V G |
dc.subject.en.en_US.fl_str_mv |
Malaria Malaria elimination Non-human primates Plasmodium vivax Zoonotic cycle |
topic |
Malaria Malaria elimination Non-human primates Plasmodium vivax Zoonotic cycle |
description |
Background: The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding Plasmodium vivax infected NHPs adds even more concern. Methods: Both Free-living monkeys in forest fragments inside the urban area and captive monkeys from a local zoo had blood samples tested for Plasmodium species. Results: In this study, among the Neotropical monkeys tested, three (4.4%), one captive and two free-living, were found to be naturally infected by P. vivax. Conclusion: This important finding indicates that it is necessary to estimate the extent to which P. vivax NHP infection contributes to the maintenance of malaria transmission to humans. Therefore, the discussion on wildlife conservation and management must be incorporated into the malaria elimination agenda. |
publishDate |
2022 |
dc.date.issued.fl_str_mv |
2022 |
dc.date.accessioned.fl_str_mv |
2023-02-07T17:48:34Z |
dc.date.available.fl_str_mv |
2023-02-07T17:48:34Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
CHAVES, Bárbara Aparecida et al. Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? Malar J., v. 21, n. 1, 343, 2022. doi: 10.1186/s12936-022-04349-6. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/56932 |
dc.identifier.issn.en_US.fl_str_mv |
1475-2875 |
identifier_str_mv |
CHAVES, Bárbara Aparecida et al. Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? Malar J., v. 21, n. 1, 343, 2022. doi: 10.1186/s12936-022-04349-6. 1475-2875 |
url |
https://www.arca.fiocruz.br/handle/icict/56932 |
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eng |
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eng |
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BioMed Central |
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BioMed Central |
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