Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?

Detalhes bibliográficos
Autor(a) principal: Chaves, Bárbara Aparecida
Data de Publicação: 2022
Outros Autores: Alvarenga, Denise Anete Madureira de, Pereira, Matheus de Oliveira Costa, Gordo, Marcelo, Silva, Emanuelle L Da, Costa, Edson Rodrigues, Medeiros, Aline Souza de Menezes, Pedrosa, Igor José Martins, Brito, Daniela, Lima, Maurício Teixeira, Mourão, Maria Paula, Monteiro, Wuelton M, Vasilakis, Nikos, Brito, Cristiana Ferreira Alves de, Melo, Gisely C, Lacerda, Marcus V G
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/56932
Resumo: Background: The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding Plasmodium vivax infected NHPs adds even more concern. Methods: Both Free-living monkeys in forest fragments inside the urban area and captive monkeys from a local zoo had blood samples tested for Plasmodium species. Results: In this study, among the Neotropical monkeys tested, three (4.4%), one captive and two free-living, were found to be naturally infected by P. vivax. Conclusion: This important finding indicates that it is necessary to estimate the extent to which P. vivax NHP infection contributes to the maintenance of malaria transmission to humans. Therefore, the discussion on wildlife conservation and management must be incorporated into the malaria elimination agenda.
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spelling Chaves, Bárbara AparecidaAlvarenga, Denise Anete Madureira dePereira, Matheus de Oliveira CostaGordo, MarceloSilva, Emanuelle L DaCosta, Edson RodriguesMedeiros, Aline Souza de MenezesPedrosa, Igor José MartinsBrito, DanielaLima, Maurício TeixeiraMourão, Maria PaulaMonteiro, Wuelton MVasilakis, NikosBrito, Cristiana Ferreira Alves deMelo, Gisely CLacerda, Marcus V G2023-02-07T17:48:34Z2023-02-07T17:48:34Z2022CHAVES, Bárbara Aparecida et al. Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? Malar J., v. 21, n. 1, 343, 2022. doi: 10.1186/s12936-022-04349-6.1475-2875https://www.arca.fiocruz.br/handle/icict/56932engBioMed CentralIs zoonotic Plasmodium vivax malaria an obstacle for disease elimination?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBackground: The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding Plasmodium vivax infected NHPs adds even more concern. Methods: Both Free-living monkeys in forest fragments inside the urban area and captive monkeys from a local zoo had blood samples tested for Plasmodium species. Results: In this study, among the Neotropical monkeys tested, three (4.4%), one captive and two free-living, were found to be naturally infected by P. vivax. Conclusion: This important finding indicates that it is necessary to estimate the extent to which P. vivax NHP infection contributes to the maintenance of malaria transmission to humans. Therefore, the discussion on wildlife conservation and management must be incorporated into the malaria elimination agenda.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/do Estado do Amazonas. Manaus, AM, Brazil/Universidade Federal do Amazonas. Programa de Pós-Graduação em Ciências da Saúde. Manaus, AM, Brazil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de pesquisa em Biologia molecular e imunologia da Malária. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de pesquisa em Biologia molecular e imunologia da Malária. Belo Horizonte, MG, Brazil.Universidade Federal do Amazonas. Instituto de Ciências Biológicas. Laboratório de Biologia da Conservação. Projeto Sauim-de-Coleira. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil.Universidade Federal do Amazonas. Instituto de Ciências Biológicas. Laboratório de Biologia da Conservação. Projeto Sauim-de-Coleira. Manaus, AM, Brazil/Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil.Universidade Federal do Amazonas. Instituto de Ciências Biológicas. Laboratório de Biologia da Conservação. Projeto Sauim-de-Coleira. Manaus, AM, Brazil/Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/Universidade Federal do Amazonas. Programa de Pós-Graduação em Ciências da Saúde. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, BrazilFundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/Universidade do Estado do Amazonas. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/Universidade do Estado do Amazonas. Manaus, AM, Brazil.Department of Pathology. Center for Biodefense and Emerging Infectious Diseases. Center for Tropical Diseases. Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX, USA.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de pesquisa em Biologia molecular e imunologia da Malária. Belo Horizonte, MG, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/Universidade do Estado do Amazonas. Manaus, AM, Brazil.Fundação de Medicina Tropical Doutor Heitor. Instituto de Pesquisas Clínicas Carlos Borborema. Manaus, AM, Brazil/Fundação Oswaldo Cruz. Instituto Leônidas & Maria Deane. Manaus, AM, Brazil.MalariaMalaria eliminationNon-human primatesPlasmodium vivaxZoonotic cycleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/56932/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALIs zoonotic Plasmodium vivax malaria an.pdfIs zoonotic Plasmodium vivax malaria an.pdfapplication/pdf1067647https://www.arca.fiocruz.br/bitstream/icict/56932/2/Is%20zoonotic%20Plasmodium%20vivax%20malaria%20an.pdf5048f3e28ac2b542e928e75a5dcff1adMD52icict/569322023-02-07 14:48:35.878oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-02-07T17:48:35Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?
title Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?
spellingShingle Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?
Chaves, Bárbara Aparecida
Malaria
Malaria elimination
Non-human primates
Plasmodium vivax
Zoonotic cycle
title_short Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?
title_full Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?
title_fullStr Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?
title_full_unstemmed Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?
title_sort Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?
author Chaves, Bárbara Aparecida
author_facet Chaves, Bárbara Aparecida
Alvarenga, Denise Anete Madureira de
Pereira, Matheus de Oliveira Costa
Gordo, Marcelo
Silva, Emanuelle L Da
Costa, Edson Rodrigues
Medeiros, Aline Souza de Menezes
Pedrosa, Igor José Martins
Brito, Daniela
Lima, Maurício Teixeira
Mourão, Maria Paula
Monteiro, Wuelton M
Vasilakis, Nikos
Brito, Cristiana Ferreira Alves de
Melo, Gisely C
Lacerda, Marcus V G
author_role author
author2 Alvarenga, Denise Anete Madureira de
Pereira, Matheus de Oliveira Costa
Gordo, Marcelo
Silva, Emanuelle L Da
Costa, Edson Rodrigues
Medeiros, Aline Souza de Menezes
Pedrosa, Igor José Martins
Brito, Daniela
Lima, Maurício Teixeira
Mourão, Maria Paula
Monteiro, Wuelton M
Vasilakis, Nikos
Brito, Cristiana Ferreira Alves de
Melo, Gisely C
Lacerda, Marcus V G
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Chaves, Bárbara Aparecida
Alvarenga, Denise Anete Madureira de
Pereira, Matheus de Oliveira Costa
Gordo, Marcelo
Silva, Emanuelle L Da
Costa, Edson Rodrigues
Medeiros, Aline Souza de Menezes
Pedrosa, Igor José Martins
Brito, Daniela
Lima, Maurício Teixeira
Mourão, Maria Paula
Monteiro, Wuelton M
Vasilakis, Nikos
Brito, Cristiana Ferreira Alves de
Melo, Gisely C
Lacerda, Marcus V G
dc.subject.en.en_US.fl_str_mv Malaria
Malaria elimination
Non-human primates
Plasmodium vivax
Zoonotic cycle
topic Malaria
Malaria elimination
Non-human primates
Plasmodium vivax
Zoonotic cycle
description Background: The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding Plasmodium vivax infected NHPs adds even more concern. Methods: Both Free-living monkeys in forest fragments inside the urban area and captive monkeys from a local zoo had blood samples tested for Plasmodium species. Results: In this study, among the Neotropical monkeys tested, three (4.4%), one captive and two free-living, were found to be naturally infected by P. vivax. Conclusion: This important finding indicates that it is necessary to estimate the extent to which P. vivax NHP infection contributes to the maintenance of malaria transmission to humans. Therefore, the discussion on wildlife conservation and management must be incorporated into the malaria elimination agenda.
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-02-07T17:48:34Z
dc.date.available.fl_str_mv 2023-02-07T17:48:34Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CHAVES, Bárbara Aparecida et al. Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? Malar J., v. 21, n. 1, 343, 2022. doi: 10.1186/s12936-022-04349-6.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/56932
dc.identifier.issn.en_US.fl_str_mv 1475-2875
identifier_str_mv CHAVES, Bárbara Aparecida et al. Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? Malar J., v. 21, n. 1, 343, 2022. doi: 10.1186/s12936-022-04349-6.
1475-2875
url https://www.arca.fiocruz.br/handle/icict/56932
dc.language.iso.fl_str_mv eng
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dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
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