Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?

Detalhes bibliográficos
Autor(a) principal: Val,Fernando Fonseca
Data de Publicação: 2014
Outros Autores: Sampaio,Vanderson Souza, Cassera,Maria Belén, Andrade,Raquel Tapajós, Tauil,Pedro Luiz, Monteiro,Wuelton Marcelo, Lacerda,Marcus Vinícius Guimarães
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500522
Resumo: In the 1950s, the strategy of adding chloroquine to food salt as a prophylaxis against malaria was considered to be a successful tool. However, with the development of Plasmodium resistance in the Brazilian Amazon, this control strategy was abandoned. More than 50 years later, asexual stage resistance can be avoided by screening for antimalarial drugs that have a selective action against gametocytes, thus old prophylactic measures can be revisited. The efficacy of the old methods should be tested as complementary tools for the elimination of malaria.
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spelling Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?malariaPlasmodiumeliminationcontrolantimalarialssaltIn the 1950s, the strategy of adding chloroquine to food salt as a prophylaxis against malaria was considered to be a successful tool. However, with the development of Plasmodium resistance in the Brazilian Amazon, this control strategy was abandoned. More than 50 years later, asexual stage resistance can be avoided by screening for antimalarial drugs that have a selective action against gametocytes, thus old prophylactic measures can be revisited. The efficacy of the old methods should be tested as complementary tools for the elimination of malaria.Instituto Oswaldo Cruz, Ministério da Saúde2014-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500522Memórias do Instituto Oswaldo Cruz v.109 n.5 2014reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/0074-0276140240info:eu-repo/semantics/openAccessVal,Fernando FonsecaSampaio,Vanderson SouzaCassera,Maria BelénAndrade,Raquel TapajósTauil,Pedro LuizMonteiro,Wuelton MarceloLacerda,Marcus Vinícius Guimarãeseng2020-04-25T17:51:46Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:19:43.001Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?
title Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?
spellingShingle Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?
Val,Fernando Fonseca
malaria
Plasmodium
elimination
control
antimalarials
salt
title_short Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?
title_full Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?
title_fullStr Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?
title_full_unstemmed Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?
title_sort Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?
author Val,Fernando Fonseca
author_facet Val,Fernando Fonseca
Sampaio,Vanderson Souza
Cassera,Maria Belén
Andrade,Raquel Tapajós
Tauil,Pedro Luiz
Monteiro,Wuelton Marcelo
Lacerda,Marcus Vinícius Guimarães
author_role author
author2 Sampaio,Vanderson Souza
Cassera,Maria Belén
Andrade,Raquel Tapajós
Tauil,Pedro Luiz
Monteiro,Wuelton Marcelo
Lacerda,Marcus Vinícius Guimarães
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Val,Fernando Fonseca
Sampaio,Vanderson Souza
Cassera,Maria Belén
Andrade,Raquel Tapajós
Tauil,Pedro Luiz
Monteiro,Wuelton Marcelo
Lacerda,Marcus Vinícius Guimarães
dc.subject.por.fl_str_mv malaria
Plasmodium
elimination
control
antimalarials
salt
topic malaria
Plasmodium
elimination
control
antimalarials
salt
dc.description.none.fl_txt_mv In the 1950s, the strategy of adding chloroquine to food salt as a prophylaxis against malaria was considered to be a successful tool. However, with the development of Plasmodium resistance in the Brazilian Amazon, this control strategy was abandoned. More than 50 years later, asexual stage resistance can be avoided by screening for antimalarial drugs that have a selective action against gametocytes, thus old prophylactic measures can be revisited. The efficacy of the old methods should be tested as complementary tools for the elimination of malaria.
description In the 1950s, the strategy of adding chloroquine to food salt as a prophylaxis against malaria was considered to be a successful tool. However, with the development of Plasmodium resistance in the Brazilian Amazon, this control strategy was abandoned. More than 50 years later, asexual stage resistance can be avoided by screening for antimalarial drugs that have a selective action against gametocytes, thus old prophylactic measures can be revisited. The efficacy of the old methods should be tested as complementary tools for the elimination of malaria.
publishDate 2014
dc.date.none.fl_str_mv 2014-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500522
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500522
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0074-0276140240
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.109 n.5 2014
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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