Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2009 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/33737 |
Resumo: | O artigo encontra-se disponível para download no SciELO. |
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Castro-Costa, Carlos Maurício deAraújo, Abelardo de Queiroz CamposCâmara, Carlos C.Ferreira, Ayrton S.Santos, Terezinha de Jesus T.Castro-Costa, Samuel Bovy deAlcântara, Raimundo Neudson M.Taylor, Graham P.2019-06-30T17:28:38Z2019-06-30T17:28:38Z2009CASTRO-COSTA, Carlos Maurício de et al. Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients. Arquivos de Neuro-Psiquiatria, v. 67, 3B, p. 866-870, 2009.0022-3050https://www.arca.fiocruz.br/handle/icict/3373710.1590/S0004-282X20090005000161468-330XO artigo encontra-se disponível para download no SciELO.Objetivo: A Paraparesia Espástica Tropical/Mielopatia Associada ao HTLV-I (PET/MAH) é uma mielopatia crônica, e a dor tem sido mencionada como um sintoma sensitivo freqüente nessa condição. Os autores objetivam analisar esse sintoma numa série de pacientes com PET/MAH. Método: Para isso, 46 pacientes foram analisados considerando características demográficas e clínicas, e queixa de dor do ponto de vista da descrição verbal, tempo de início e classificação, correlacionados com o grau de incapacitação motora e o tipo de dor. Resultados: Dentre os 46 pacientes com PET/MAH, 28 (60,8%) se queixavam de dor, predominando na fase inicial da doença. A maioria dos pacientes evidenciou características de dor neuropática, correlacionada com aumento da incapacitação motora. Conclusão: A dor em pacientes com PET/MAH é um sintoma freqüente e inicial, sendo o tipo neuropático predominante (57,1%) e em paralelo com maior incapacitação. O envolvimento patogênico das citocinas poderá possivelmente estar relacionado com o significado desse sintoma nessa condição clínica.Objective: Tropical Spastic Paraparesis/HTLV-I Associated Myelopathy (TSP/HAM) is a chronic myelopathy, and pain has been mentioned as a frequent sensory symptom in this condition. The authors aimed at analyzing this symptom in a TSP/HAM patients series. Method: For this, 46 patients were analyzed considering demographic and clinical characteristics and complaint of pain as to verbal description, time of onset and classification, correlated with the degree of motor disability and type of pain. Results: Among the 46 TSP/HAM patients, 28 (60.8%) complained of pain, predominant in the early phase of the disease. Most of the patients exhibited neuropathic characteristics of pain, correlated with increased motor disability. Conclusion: Pain in TSP/HAM patients is a frequent and early symptom, and the neuropathic type is predominant (57.1%) and paralleled with increased incapacitation. The pathogenic involvement of cytokines may possibly be involved in the meaning of this symptom in this condition.Universidade Federal do Ceará. Instituto de Biomedicina. Departamento de Fisiologia e Farmacologia. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisas Clínicas Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Rio de Janeiro RJ, Brasil.Universidade Federal do Ceará. Instituto de Biomedicina. Departamento de Fisiologia e Farmacologia. Fortaleza, CE, Brasil.Universidade Federal do Ceará. Instituto de Biomedicina. Departamento de Fisiologia e Farmacologia. Fortaleza, CE, Brasil.Universidade Federal do Ceará. Instituto de Biomedicina. Departamento de Fisiologia e Farmacologia. Fortaleza, CE, Brasil.Universidade Federal do Ceará. Instituto de Biomedicina. Departamento de Fisiologia e Farmacologia. Fortaleza, CE, Brasil.Universidade Federal do Ceará. Instituto de Biomedicina. Departamento de Fisiologia e Farmacologia. Fortaleza, CE, Brasil.Imperial College London. Department of Genito-Urinary Medicine and Communicable Diseases. London, UK.engBMJ Publishing GroupPET/MAHHTLV-IDorNociceptiva inflamatória e neuropáticaCitocinasTSP/HAMHTLV-IPainInflammatory nociceptive and neuropathicCytokinesPain in tropical spastic paraparesis/HTLV-I associated myelopathy patientsDor em pacientes com paraparesia espástica tropical/mielopatia associada ao HTLV-Iinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/33737/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Castro-Costa_Carlos_etal_INI_2009.pdfve_Castro-Costa_Carlos_etal_INI_2009.pdfapplication/pdf202062https://www.arca.fiocruz.br/bitstream/icict/33737/2/ve_Castro-Costa_Carlos_etal_INI_2009.pdfc999a2e76d3fb09b2df6498f18822808MD52TEXTve_Castro-Costa_Carlos_etal_INI_2009.pdf.txtve_Castro-Costa_Carlos_etal_INI_2009.pdf.txtExtracted texttext/plain23466https://www.arca.fiocruz.br/bitstream/icict/33737/3/ve_Castro-Costa_Carlos_etal_INI_2009.pdf.txt675b8f6972fc7cd040a61b89356806e8MD53icict/337372019-07-01 02:02:28.828oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-07-01T05:02:28Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients |
| dc.title.alternative.pt_BR.fl_str_mv |
Dor em pacientes com paraparesia espástica tropical/mielopatia associada ao HTLV-I |
| title |
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients |
| spellingShingle |
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients Castro-Costa, Carlos Maurício de PET/MAH HTLV-I Dor Nociceptiva inflamatória e neuropática Citocinas TSP/HAM HTLV-I Pain Inflammatory nociceptive and neuropathic Cytokines |
| title_short |
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients |
| title_full |
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients |
| title_fullStr |
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients |
| title_full_unstemmed |
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients |
| title_sort |
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients |
| author |
Castro-Costa, Carlos Maurício de |
| author_facet |
Castro-Costa, Carlos Maurício de Araújo, Abelardo de Queiroz Campos Câmara, Carlos C. Ferreira, Ayrton S. Santos, Terezinha de Jesus T. Castro-Costa, Samuel Bovy de Alcântara, Raimundo Neudson M. Taylor, Graham P. |
| author_role |
author |
| author2 |
Araújo, Abelardo de Queiroz Campos Câmara, Carlos C. Ferreira, Ayrton S. Santos, Terezinha de Jesus T. Castro-Costa, Samuel Bovy de Alcântara, Raimundo Neudson M. Taylor, Graham P. |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Castro-Costa, Carlos Maurício de Araújo, Abelardo de Queiroz Campos Câmara, Carlos C. Ferreira, Ayrton S. Santos, Terezinha de Jesus T. Castro-Costa, Samuel Bovy de Alcântara, Raimundo Neudson M. Taylor, Graham P. |
| dc.subject.other.pt_BR.fl_str_mv |
PET/MAH HTLV-I Dor Nociceptiva inflamatória e neuropática Citocinas |
| topic |
PET/MAH HTLV-I Dor Nociceptiva inflamatória e neuropática Citocinas TSP/HAM HTLV-I Pain Inflammatory nociceptive and neuropathic Cytokines |
| dc.subject.en.pt_BR.fl_str_mv |
TSP/HAM HTLV-I Pain Inflammatory nociceptive and neuropathic Cytokines |
| description |
O artigo encontra-se disponível para download no SciELO. |
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2009 |
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2009 |
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2019-06-30T17:28:38Z |
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2019-06-30T17:28:38Z |
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info:eu-repo/semantics/article |
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article |
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| dc.identifier.citation.fl_str_mv |
CASTRO-COSTA, Carlos Maurício de et al. Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients. Arquivos de Neuro-Psiquiatria, v. 67, 3B, p. 866-870, 2009. |
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https://www.arca.fiocruz.br/handle/icict/33737 |
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0022-3050 |
| dc.identifier.doi.none.fl_str_mv |
10.1590/S0004-282X2009000500016 |
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1468-330X |
| identifier_str_mv |
CASTRO-COSTA, Carlos Maurício de et al. Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients. Arquivos de Neuro-Psiquiatria, v. 67, 3B, p. 866-870, 2009. 0022-3050 10.1590/S0004-282X2009000500016 1468-330X |
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BMJ Publishing Group |
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BMJ Publishing Group |
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