A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality

Detalhes bibliográficos
Autor(a) principal: Silva, Walter A. Eyer
Data de Publicação: 2005
Outros Autores: Morgado, Mariza G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/44566
Resumo: Universidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Rio de Janeiro, RJ, Brasil / Programa Municipal de HIV/Aids de Miracema. Miracema, RJ, Brasil.
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spelling Silva, Walter A. EyerMorgado, Mariza G.2020-11-20T20:24:01Z2020-11-20T20:24:01Z2005SILVA, Walter A. Eyer; MORGADO, Mariza G. A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 8, p. 869-873, Dec. 2005.0074-0276https://www.arca.fiocruz.br/handle/icict/4456610.1590/S0074-027620050008000081678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Resistência antirretroviralGenotipagemSmall municipalitiesVírus da imunodeficiência humana tipo 1SubtiposBrasilGenotypingAntiretroviral resistanceHuman immunodeficiency virus type-1Small municipalitiesSubtypesBrazilA genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipalityinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Rio de Janeiro, RJ, Brasil / Programa Municipal de HIV/Aids de Miracema. Miracema, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Aids & Imunologia Molecular. Rio de Janeiro, RJ, Brasil.In Brazil, surveillance studies on antiretroviral drug resistance among drug-naïve and treatment-experienced patients have focused primarily on patients living in large urban centers. As the epidemic spreads towards small municipalities and the innermost parts of the country, it will be essential to monitor the prevalence of antiretroviral drug resistance in these areas. We report the first survey on the prevalence of antiretroviral drug resistance in a small Brazilian municipality. Between July 1999 and March 2005, 72 adult human immunodeficiency virus type-1(HIV-1)-infected patients received care at the Municipal HIV/AIDS Program of the small, southeastern municipality of Miracema, state of Rio de Janeiro. A genotyping study of antiretroviral drug resistance was performed in 54 patients. Among 27 samples from treatment-experienced patients, 9 (33.3%) harbored strains with reduced drug susceptibility. Among these, 6 had reduced susceptibility to reverse transcriptase (RT) inhibitors and 3 to both RT and protease inhibitors. No primary antiretroviral drug resistance was recorded among 27 drug-naïve subjects. 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dc.title.pt_BR.fl_str_mv A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality
title A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality
spellingShingle A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality
Silva, Walter A. Eyer
Resistência antirretroviral
Genotipagem
Small municipalities
Vírus da imunodeficiência humana tipo 1
Subtipos
Brasil
Genotyping
Antiretroviral resistance
Human immunodeficiency virus type-1
Small municipalities
Subtypes
Brazil
title_short A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality
title_full A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality
title_fullStr A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality
title_full_unstemmed A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality
title_sort A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality
author Silva, Walter A. Eyer
author_facet Silva, Walter A. Eyer
Morgado, Mariza G.
author_role author
author2 Morgado, Mariza G.
author2_role author
dc.contributor.author.fl_str_mv Silva, Walter A. Eyer
Morgado, Mariza G.
dc.subject.other.pt_BR.fl_str_mv Resistência antirretroviral
Genotipagem
Small municipalities
Vírus da imunodeficiência humana tipo 1
Subtipos
Brasil
topic Resistência antirretroviral
Genotipagem
Small municipalities
Vírus da imunodeficiência humana tipo 1
Subtipos
Brasil
Genotyping
Antiretroviral resistance
Human immunodeficiency virus type-1
Small municipalities
Subtypes
Brazil
dc.subject.en.pt_BR.fl_str_mv Genotyping
Antiretroviral resistance
Human immunodeficiency virus type-1
Small municipalities
Subtypes
Brazil
description Universidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Rio de Janeiro, RJ, Brasil / Programa Municipal de HIV/Aids de Miracema. Miracema, RJ, Brasil.
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2020-11-20T20:24:01Z
dc.date.available.fl_str_mv 2020-11-20T20:24:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, Walter A. Eyer; MORGADO, Mariza G. A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 8, p. 869-873, Dec. 2005.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/44566
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762005000800008
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv SILVA, Walter A. Eyer; MORGADO, Mariza G. A genotyping study of human immunodeficiency virus type-1 drug resistance in a small Brazilian municipality. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 8, p. 869-873, Dec. 2005.
0074-0276
10.1590/S0074-02762005000800008
1678-8060
url https://www.arca.fiocruz.br/handle/icict/44566
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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