Lymphocyte subset reference intervals in blood donors from northeastern Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2015 |
| Outros Autores: | , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/15240 |
Resumo: | Universidade Federal da Bahia. Hospitalar Professor Edgard Santos. Laboratório de Pesquisa em Infectologia. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, Brasil |
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Torres, Alex José LeiteCisneiros, PatriciaGuedes, RosaGrassi, Maria Fernanda RiosMeyer, Roberto JoséBendicho, Maria TeresitaLopes, Tais Gardenia Santos LemosFélix, GabrielaMartins Netto, EduardoBrites, CarlosAbe-Sandes, KiyokoBrandão, ClaudioNeves, Neuza Maria AlcântaraFreire, Songeli Menezes2016-08-11T15:54:55Z2016-08-11T15:54:55Z2015TORRES, A. J. L. et al. Lymphocyte subset reference intervals in blood donors from northeastern Brazil. Anais da Academia Brasileira de Ciências, v. 87, n. 2, p. 1019-1025, 2015.0001-3765https://www.arca.fiocruz.br/handle/icict/15240engAcademia Brasileira de CiênciasLymphocyte subset reference intervals in blood donors from northeastern Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal da Bahia. Hospitalar Professor Edgard Santos. Laboratório de Pesquisa em Infectologia. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Imunologia e Biologia Molecular. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Imunologia e Biologia Molecular. Salvador, BA, BrasilEscola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Imunologia e Biologia Molecular. Salvador, BA / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, Brasil / Ministério da Ciência, Tecnologia e Inovação. Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais. Serviço de Imunologia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Imunologia e Biologia Molecular. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil / Universidade do Estado da Bahia. UNEB. Departamento de Ciências da Vida. Salvador, BA, BrasilUniversidade Federal da Bahia. Hospitalar Professor Edgard Santos. Laboratório de Pesquisa em Infectologia. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, BrasilUniversidade Federal da Bahia. Hospitalar Professor Edgard Santos. Laboratório de Pesquisa em Infectologia. Salvador, BA, Brasil /Universidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Imunologia e Biologia Molecular. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Imunologia e Biologia Molecular. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, Brasil / Ministério da Ciência, Tecnologia e Inovação. Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais. Serviço de Imunologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Hospitalar Professor Edgard Santos. Laboratório de Pesquisa em Infectologia. Salvador, BA, Brasil / Universidade do Estado da Bahia. UNEB. Departamento de Ciências da Vida. Salvador, BA, BrasilFundação de Hematologia e Hemoterapia da Bahia. HEMOBA. Hospital Geral. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Imunologia e Biologia Molecular. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, Brasil / Ministério da Ciência, Tecnologia e Inovação. Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais. INCT-DT. Serviço de Imunologia. Salvador, BA, BrasilThe reference intervals for leukocytes and lymphocytes currently used by most clinical laboratories present limitations as they are primarily derived from individuals of North American and European origin. The objective this study was to determine reference values for peripheral blood B lymphocytes, T lymphocyte subsets (CD4+, CD8+, naïve, memory, regulatory, TCRαβ and TCRγδ+) and NK cells from blood donors in Salvador-Bahia, Brazil. Results: The proportion of included male subjects was 73.7% and the median ages of males (34) and females (35) were found to be similar. Absolute counts total lymphocytes subsets to both gender was 1,956 (1,060-4,186) cells and relative values 34%. The T CD4+ and T CD8+ lymphocytes relative values was 51% (20-62) and 24% (9-28), respectively. The most statistically significant finding observed was a higher percentage of B lymphocytes (p=0.03) in females. Commonly cited subset reference intervals were found to be consistent with values in several populations from different geographic areas.Lymphocyte subsetsReference valuesFlow cytometryBrazilBlood donorsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/15240/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALTorres AJL Lymphocyte subset....pdfTorres AJL Lymphocyte subset....pdfapplication/pdf252170https://www.arca.fiocruz.br/bitstream/icict/15240/2/Torres%20AJL%20Lymphocyte%20subset....pdfc4550d55bb8e21289e7c9356b043b334MD52TEXTTorres AJL Lymphocyte subset....pdf.txtTorres AJL Lymphocyte subset....pdf.txtExtracted texttext/plain26765https://www.arca.fiocruz.br/bitstream/icict/15240/3/Torres%20AJL%20Lymphocyte%20subset....pdf.txt92a9a7534c28ceffd95db658f1caac21MD53icict/152402023-03-15 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| dc.title.pt_BR.fl_str_mv |
Lymphocyte subset reference intervals in blood donors from northeastern Brazil |
| title |
Lymphocyte subset reference intervals in blood donors from northeastern Brazil |
| spellingShingle |
Lymphocyte subset reference intervals in blood donors from northeastern Brazil Torres, Alex José Leite Lymphocyte subsets Reference values Flow cytometry Brazil Blood donors |
| title_short |
Lymphocyte subset reference intervals in blood donors from northeastern Brazil |
| title_full |
Lymphocyte subset reference intervals in blood donors from northeastern Brazil |
| title_fullStr |
Lymphocyte subset reference intervals in blood donors from northeastern Brazil |
| title_full_unstemmed |
Lymphocyte subset reference intervals in blood donors from northeastern Brazil |
| title_sort |
Lymphocyte subset reference intervals in blood donors from northeastern Brazil |
| author |
Torres, Alex José Leite |
| author_facet |
Torres, Alex José Leite Cisneiros, Patricia Guedes, Rosa Grassi, Maria Fernanda Rios Meyer, Roberto José Bendicho, Maria Teresita Lopes, Tais Gardenia Santos Lemos Félix, Gabriela Martins Netto, Eduardo Brites, Carlos Abe-Sandes, Kiyoko Brandão, Claudio Neves, Neuza Maria Alcântara Freire, Songeli Menezes |
| author_role |
author |
| author2 |
Cisneiros, Patricia Guedes, Rosa Grassi, Maria Fernanda Rios Meyer, Roberto José Bendicho, Maria Teresita Lopes, Tais Gardenia Santos Lemos Félix, Gabriela Martins Netto, Eduardo Brites, Carlos Abe-Sandes, Kiyoko Brandão, Claudio Neves, Neuza Maria Alcântara Freire, Songeli Menezes |
| author2_role |
author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Torres, Alex José Leite Cisneiros, Patricia Guedes, Rosa Grassi, Maria Fernanda Rios Meyer, Roberto José Bendicho, Maria Teresita Lopes, Tais Gardenia Santos Lemos Félix, Gabriela Martins Netto, Eduardo Brites, Carlos Abe-Sandes, Kiyoko Brandão, Claudio Neves, Neuza Maria Alcântara Freire, Songeli Menezes |
| dc.subject.en.pt_BR.fl_str_mv |
Lymphocyte subsets Reference values Flow cytometry Brazil Blood donors |
| topic |
Lymphocyte subsets Reference values Flow cytometry Brazil Blood donors |
| description |
Universidade Federal da Bahia. Hospitalar Professor Edgard Santos. Laboratório de Pesquisa em Infectologia. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, Brasil |
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2015 |
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2015 |
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2016-08-11T15:54:55Z |
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2016-08-11T15:54:55Z |
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info:eu-repo/semantics/article |
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TORRES, A. J. L. et al. Lymphocyte subset reference intervals in blood donors from northeastern Brazil. Anais da Academia Brasileira de Ciências, v. 87, n. 2, p. 1019-1025, 2015. |
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https://www.arca.fiocruz.br/handle/icict/15240 |
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0001-3765 |
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TORRES, A. J. L. et al. Lymphocyte subset reference intervals in blood donors from northeastern Brazil. Anais da Academia Brasileira de Ciências, v. 87, n. 2, p. 1019-1025, 2015. 0001-3765 |
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Academia Brasileira de Ciências |
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Academia Brasileira de Ciências |
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