Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil

Detalhes bibliográficos
Autor(a) principal: Santos, Debora Regina Lopes dos
Data de Publicação: 2011
Outros Autores: Paula, Vanessa Salete de, Oliveira, Jaqueline Mendes de, Marchevsky, Renato Sérgio, Pinto, Marcelo Alves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/30074
Resumo: Universidade Federal Rural do Rio de Janeiro. Instituto de Veterinária. Departamento de Microbiologia e Imunologia Veterinária. Laboratório de Imunologia e Virologia Veterinária. Seropédica, RJ, Brasil.
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spelling Santos, Debora Regina Lopes dosPaula, Vanessa Salete deOliveira, Jaqueline Mendes deMarchevsky, Renato SérgioPinto, Marcelo Alves2018-11-18T16:05:01Z2018-11-18T16:05:01Z2011SANTOS, Debora Regina Lopes dos; et al. Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil. Veterinary Microbiology, v.149, n.1-2, p.236-241, April 2011.0378-1135https://www.arca.fiocruz.br/handle/icict/3007410.1016/j.vetmic.2010.10.024engElseviersegurança alimentarsuínosHepatite EZoonoseBrasilSwineHepatitis EZoonosisFood safetyBrazilHepatitis E virus in swine and effluent samples from slaughterhouses in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal Rural do Rio de Janeiro. Instituto de Veterinária. Departamento de Microbiologia e Imunologia Veterinária. Laboratório de Imunologia e Virologia Veterinária. Seropédica, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Bio-Manguinhos. Laboratório de Neuro-Virulência. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.Hepatitis E is an infectious disease which virus (HEV) is highly disseminated in swine herd populations. Sporadic acute human hepatitis E cases have been associated to genotype 3 and 4 strains of HEV also reported in swine populations of endemic and non-endemic areas. With the aim to evaluate the incidence of animals with current infection of HEV, 115 bile samples were collected from three slaughterhouses under inspection by Animal Sanitary Protection Agency of Rio de Janeiro, Brazil. In parallel, effluent samples were collected from six sewage pipe exit sites of two slaughterhouses. HEV RNA was detected in 11 out of 115 (9.6%) bile samples collected and three waste samples from one slaughterhouse. Viral loads observed for bile samples varied from 10(1)-10(5) genome copies/mL and for effluent samples mean load was 10(2) genome copies/mL. Sequencing and phylogenetic analysis classified samples within genotype 3 subtype 3b closely related to the sample obtained from the first reported autochthonous human case and samples from swine of commercial herds in Brazil. Our data demonstrates that although most animals achieve slaughter age (around 20 weeks old) already immune to HEV, a significant number of animals are with current infection at commercial age. Further studies should be addressed to consider risk analysis and possible evaluation of inspection regulations considering food safety measures regarding hepatitis E zoonotic aspect in Brazil.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/30074/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALvanessas_paula_marcelopinto_etal_IOC_2011.pdfvanessas_paula_marcelopinto_etal_IOC_2011.pdfapplication/pdf327062https://www.arca.fiocruz.br/bitstream/icict/30074/2/vanessas_paula_marcelopinto_etal_IOC_2011.pdfcca9f8b8fa7606b729de769e96bf7e1fMD52TEXTvanessas_paula_marcelopinto_etal_IOC_2011.pdf.txtvanessas_paula_marcelopinto_etal_IOC_2011.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil
title Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil
spellingShingle Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil
Santos, Debora Regina Lopes dos
segurança alimentar
suínos
Hepatite E
Zoonose
Brasil
Swine
Hepatitis E
Zoonosis
Food safety
Brazil
title_short Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil
title_full Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil
title_fullStr Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil
title_full_unstemmed Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil
title_sort Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil
author Santos, Debora Regina Lopes dos
author_facet Santos, Debora Regina Lopes dos
Paula, Vanessa Salete de
Oliveira, Jaqueline Mendes de
Marchevsky, Renato Sérgio
Pinto, Marcelo Alves
author_role author
author2 Paula, Vanessa Salete de
Oliveira, Jaqueline Mendes de
Marchevsky, Renato Sérgio
Pinto, Marcelo Alves
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santos, Debora Regina Lopes dos
Paula, Vanessa Salete de
Oliveira, Jaqueline Mendes de
Marchevsky, Renato Sérgio
Pinto, Marcelo Alves
dc.subject.other.pt_BR.fl_str_mv segurança alimentar
suínos
Hepatite E
Zoonose
Brasil
topic segurança alimentar
suínos
Hepatite E
Zoonose
Brasil
Swine
Hepatitis E
Zoonosis
Food safety
Brazil
dc.subject.en.pt_BR.fl_str_mv Swine
Hepatitis E
Zoonosis
Food safety
Brazil
description Universidade Federal Rural do Rio de Janeiro. Instituto de Veterinária. Departamento de Microbiologia e Imunologia Veterinária. Laboratório de Imunologia e Virologia Veterinária. Seropédica, RJ, Brasil.
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2018-11-18T16:05:01Z
dc.date.available.fl_str_mv 2018-11-18T16:05:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SANTOS, Debora Regina Lopes dos; et al. Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil. Veterinary Microbiology, v.149, n.1-2, p.236-241, April 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/30074
dc.identifier.issn.pt_BR.fl_str_mv 0378-1135
dc.identifier.doi.none.fl_str_mv 10.1016/j.vetmic.2010.10.024
identifier_str_mv SANTOS, Debora Regina Lopes dos; et al. Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil. Veterinary Microbiology, v.149, n.1-2, p.236-241, April 2011.
0378-1135
10.1016/j.vetmic.2010.10.024
url https://www.arca.fiocruz.br/handle/icict/30074
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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