Actin cytoskeleton control of the comings and goings of T lymphocytes

Detalhes bibliográficos
Autor(a) principal: Lafouresse, F.
Data de Publicação: 2013
Outros Autores: Vasconcelos, Zilton Farias Meira de, Cotta-de-Almeida, V., Dupre, L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/8758
Resumo: 2014-11-29
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spelling Lafouresse, F.Vasconcelos, Zilton Farias Meira deCotta-de-Almeida, V.Dupre, L.2014-11-06T17:31:59Z2014-11-30T06:30:06Z2013LAFOURESSE, F. et al. Actin cytoskeleton control of the comings and goings of T lymphocytes. Tissue Antigens, Copenhagen, v. 82, n. 5, p. 301-311, 2013.0001-2815https://www.arca.fiocruz.br/handle/icict/875810.1111/tan.12193engMuskgaardActin cytoskeleton control of the comings and goings of T lymphocytesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2014-11-29INSERM. U1043. Toulouse, France / Université Toulouse III Paul-Sabatier. Centre de Physiopathologie de Toulouse Purpan. Toulouse, France / CNRS. U5282. Toulouse, France.Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Thymus. Rio de Janeiro, RJ, Brasil.INSERM. U1043. Toulouse, France / Université Toulouse III Paul-Sabatier. Centre de Physiopathologie de Toulouse Purpan. Toulouse, France / CNRS. U5282. Toulouse, France.T lymphocytes are key players of adaptive immune responses. Upon recognition of specific peptides presented by human leukocyte antigen (HLA) molecules on antigen presenting cells (APC), these cells execute subset-related functions such as killing, help and regulation. The ontogeny, the activation and the effector functions of T lymphocytes are all steps of T-lymphocyte life cycle that rely on high motility properties. These cells travel through the organism in a succession of steps, including entry into tissues, interstitial migration, APC scanning, synapse formation and tissue exit. Such ability is possible because of a plastic motility behavior, which is highly controlled in time and space. The molecular basis for the adaptable motility behavior of T lymphocytes is only starting to be unraveled. The scope of this review is to discuss recent data pointing to the key role of regulators of actin cytoskeleton remodeling in tuning distinct aspects of T-lymphocyte motility during their entry, residency and exit from tissues.Actin CytoskeletonMigrationT lymphocytesCitoesqueleto de ActinaMigraçãoLinfócitos Tinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALActin cytoskeleton control of the comings and goings of T.pdfEmbargo vencidoapplication/pdf1447640https://www.arca.fiocruz.br/bitstream/icict/8758/1/Actin%20cytoskeleton%20control%20of%20the%20comings%20and%20goings%20of%20T.pdf293482d3c53d6c8cfa2695736e513687MD51LICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/8758/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTActin cytoskeleton control of the comings and goings of T.pdf.txtActin cytoskeleton control of the comings and goings of T.pdf.txtExtracted texttext/plain59102https://www.arca.fiocruz.br/bitstream/icict/8758/3/Actin%20cytoskeleton%20control%20of%20the%20comings%20and%20goings%20of%20T.pdf.txta7522f3fb4245cbd221f86cc618a97b1MD53icict/87582022-06-24 12:19:34.252oai:www.arca.fiocruz.br:icict/8758TElDRU7Dh0EgREUgRElTVFJJQlVJw4fDg08gTsODTy1FWENMVVNJVkEKCkFvIGNvbmNvcmRhciBlIGFjZWl0YXIgZXN0YSBsaWNlbsOnYSB2b2PDqiAoYXV0b3Igb3UgZGV0ZW50b3IgZG9zIGRpcmVpdG9zIGF1dG9yYWlzKToKCmEpIERlY2xhcmEgcXVlIGNvbmhlY2UgYSBwb2zDrXRpY2EgZGUgY29weXJpZ2h0IGRhIGVkaXRvcmEgZG8gc2V1IGRvY3VtZW50by4KCmIpIERlY2xhcmEgcXVlIGNvbmhlY2UgZSBhY2VpdGEgYXMgRGlyZXRyaXplcyBwYXJhIG8gUmVwb3NpdMOzcmlvIEluc3RpdHVjaW9uYWwgZGEgRnVuZGHDp8OjbyBPc3dhbGRvIENydXogKEZJT0NSVVopLgoKYykgQ29uY2VkZSDDoCBGSU9DUlVaIG8gZGlyZWl0byBuw6NvLWV4Y2x1c2l2byBkZSBhcnF1aXZhciwgcmVwcm9kdXppciwgY29udmVydGVyIChjb21vIGRlZmluaWRvIGEgc2VndWlyKSwgY29tdW5pY2FyCiAKZS9vdSBkaXN0cmlidWlyIG5vIFJlcG9zaXTDs3JpbyBkYSBGSU9DUlVaLCBvIGRvY3VtZW50byBlbnRyZWd1ZSAoaW5jbHVpbmRvIG8gcmVzdW1vL2Fic3RyYWN0KSBlbSBmb3JtYXRvIGRpZ2l0YWwgb3UgCgpwb3IgcXVhbHF1ZXIgb3V0cm8gbWVpby4KCmQpIERlY2xhcmEgcXVlIGF1dG9yaXphIGEgRklPQ1JVWiBhIGFycXVpdmFyIG1haXMgZGUgdW1hIGPDs3BpYSBkZXN0ZSBkb2N1bWVudG8gZSBjb252ZXJ0w6otbG8sIHNlbSBhbHRlcmFyIG8gc2V1IGNvbnRlw7pkbywgCgpwYXJhIHF1YWxxdWVyIGZvcm1hdG8gZGUgYXJxdWl2bywgbWVpbyBvdSBzdXBvcnRlLCBwYXJhIGVmZWl0b3MgZGUgc2VndXJhbsOnYSwgcHJlc2VydmHDp8OjbyAoYmFja3VwKSBlIGFjZXNzby4KCmUpIERlY2xhcmEgcXVlIG8gZG9jdW1lbnRvIHN1Ym1ldGlkbyDDqSBvIHNldSB0cmFiYWxobyBvcmlnaW5hbCwgZSBxdWUgZGV0w6ltIG8gZGlyZWl0byBkZSBjb25jZWRlciBhIHRlcmNlaXJvcyBvcyBkaXJlaXRvcyAKCmNvbnRpZG9zIG5lc3RhIGxpY2Vuw6dhLiBEZWNsYXJhIHRhbWLDqW0gcXVlIGEgZW50cmVnYSBkbyBkb2N1bWVudG8gbsOjbyBpbmZyaW5nZSBvcyBkaXJlaXRvcyBkZSBxdWFscXVlciBvdXRyYSBwZXNzb2Egb3UgZW50aWRhZGUuCgpmKSBEZWNsYXJhIHF1ZSwgbm8gY2FzbyBkbyBkb2N1bWVudG8gc3VibWV0aWRvIGNvbnRlciBtYXRlcmlhbCBkbyBxdWFsIG7Do28gZGV0w6ltIG9zIGRpcmVpdG9zIGRlIGF1dG9yLCBvYnRldmUgYSBhdXRvcml6YcOnw6NvIAoKaXJyZXN0cml0YSBkbyByZXNwZWN0aXZvIGRldGVudG9yIGRlc3NlcyBkaXJlaXRvcywgcGFyYSBjZWRlciBhIEZJT0NSVVogb3MgZGlyZWl0b3MgcmVxdWVyaWRvcyBwb3IgZXN0YSBMaWNlbsOnYSBlIGF1dG9yaXphciBhIAoKdXRpbGl6w6EtbG9zIGxlZ2FsbWVudGUuIERlY2xhcmEgdGFtYsOpbSBxdWUgZXNzZSBtYXRlcmlhbCBjdWpvcyBkaXJlaXRvcyBzw6NvIGRlIHRlcmNlaXJvcyBlc3TDoSBjbGFyYW1lbnRlIGlkZW50aWZpY2FkbyBlIHJlY29uaGVjaWRvIAoKbm8gdGV4dG8gb3UgY29udGXDumRvIGRvIGRvY3VtZW50byBlbnRyZWd1ZS4KCmcpIFNFIE8gRE9DVU1FTlRPIEVOVFJFR1VFIMOJIEJBU0VBRE8gRU0gVFJBQkFMSE8gRklOQU5DSUFETyBPVSBBUE9JQURPIFBPUiBPVVRSQSBJTlNUSVRVScOHw4NPIFFVRSBOw4NPIEEgRklPQ1JVWiwgREVDTEFSQSBRVUUgQ1VNUFJJVSAKClFVQUlTUVVFUiBPQlJJR0HDh8OVRVMgRVhJR0lEQVMgUEVMTyBSRVNQRUNUSVZPIENPTlRSQVRPIE9VIEFDT1JETy4gQSBGSU9DUlVaIGlkZW50aWZpY2Fyw6EgY2xhcmFtZW50ZSBvKHMpIG5vbWUocykgZG8ocykgYXV0b3IoZXMpIGRvcyAKCmRpcmVpdG9zIGRvIGRvY3VtZW50byBlbnRyZWd1ZSBlIG7Do28gZmFyw6EgcXVhbHF1ZXIgYWx0ZXJhw6fDo28sIHBhcmEgYWzDqW0gZG8gcHJldmlzdG8gbmEgYWzDrW5lYSBjKS4KRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T15:19:34Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Actin cytoskeleton control of the comings and goings of T lymphocytes
title Actin cytoskeleton control of the comings and goings of T lymphocytes
spellingShingle Actin cytoskeleton control of the comings and goings of T lymphocytes
Lafouresse, F.
Actin Cytoskeleton
Migration
T lymphocytes
Citoesqueleto de Actina
Migração
Linfócitos T
title_short Actin cytoskeleton control of the comings and goings of T lymphocytes
title_full Actin cytoskeleton control of the comings and goings of T lymphocytes
title_fullStr Actin cytoskeleton control of the comings and goings of T lymphocytes
title_full_unstemmed Actin cytoskeleton control of the comings and goings of T lymphocytes
title_sort Actin cytoskeleton control of the comings and goings of T lymphocytes
author Lafouresse, F.
author_facet Lafouresse, F.
Vasconcelos, Zilton Farias Meira de
Cotta-de-Almeida, V.
Dupre, L.
author_role author
author2 Vasconcelos, Zilton Farias Meira de
Cotta-de-Almeida, V.
Dupre, L.
author2_role author
author
author
dc.contributor.author.fl_str_mv Lafouresse, F.
Vasconcelos, Zilton Farias Meira de
Cotta-de-Almeida, V.
Dupre, L.
dc.subject.en.pt_BR.fl_str_mv Actin Cytoskeleton
Migration
T lymphocytes
topic Actin Cytoskeleton
Migration
T lymphocytes
Citoesqueleto de Actina
Migração
Linfócitos T
dc.subject.decs.pt_BR.fl_str_mv Citoesqueleto de Actina
Migração
Linfócitos T
description 2014-11-29
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2014-11-06T17:31:59Z
dc.date.available.fl_str_mv 2014-11-30T06:30:06Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LAFOURESSE, F. et al. Actin cytoskeleton control of the comings and goings of T lymphocytes. Tissue Antigens, Copenhagen, v. 82, n. 5, p. 301-311, 2013.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/8758
dc.identifier.issn.pt_BR.fl_str_mv 0001-2815
dc.identifier.doi.pt_BR.fl_str_mv 10.1111/tan.12193
identifier_str_mv LAFOURESSE, F. et al. Actin cytoskeleton control of the comings and goings of T lymphocytes. Tissue Antigens, Copenhagen, v. 82, n. 5, p. 301-311, 2013.
0001-2815
10.1111/tan.12193
url https://www.arca.fiocruz.br/handle/icict/8758
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Muskgaard
publisher.none.fl_str_mv Muskgaard
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/8758/2/license.txt
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