Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus

Detalhes bibliográficos
Autor(a) principal: Andrade, Laura Medeiros
Data de Publicação: 2021
Outros Autores: Meio, Maria Dalva Baker, Gomes Jr, Saint Clair, Souza, Juliana Paiva, Figueiredo, Mirza R., Costa, Roozemeria Pereira, Brasil, Patricia, Nielsen-Saines, Karin, Brickley, Elizabeth, Moreira, Maria Elisabeth Lopes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/49089
Resumo: Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Departamento de Neonatologia. Rio de Janeiro, RJ, Brasil.
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spelling Andrade, Laura MedeirosMeio, Maria Dalva BakerGomes Jr, Saint ClairSouza, Juliana PaivaFigueiredo, Mirza R.Costa, Roozemeria PereiraBrasil, PatriciaNielsen-Saines, KarinBrickley, ElizabethMoreira, Maria Elisabeth Lopes2021-09-16T13:37:00Z2021-09-16T13:37:00Z2021ANDRADE, Laura Medeiros et al. Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus. Acta paediatrica, v. 110, n. 8, p. 2375-2381, 2021.0803-5253https://www.arca.fiocruz.br/handle/icict/4908910.1111/apa.15878engWileyLanguage delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virusinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Fernandes Figueira. Departamento de Neonatologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Departamento de Neonatologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.University of California Los Angeles. Los Angeles, CA, USA.London School of Hygiene & Tropical Medicine. London, UK.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Aim: Our aim was to analyse 12-month outcomes of children who were prenatally exposed to the Zika virus and asymptomatic at birth. Methods: This was an observational, exploratory study of infants exposed to the Zika virus during gestation and born between March 2016 and April 2017 without congenital Zika syndrome. They were followed until the age of 22 months. The outcome measure was neurodevelopment at 12 months of life, which was evaluated with the Bayley Scales of Infant and Toddler Development, Third edition (Bayley-III). The scores were adjusted for maternal education and prematurity. Results: A total of 96 infants were included in the study and 35.4% scored below the normal range in at least one Bayley-III domain. The majority (91.2%) of the infants with delayed scores presented with language delay, which was not associated with the gestational age at exposure. Receptive language was more affected by exposure than expressive language (27.0% vs 19.8%). There was a direct, and significant, association between the head circumference Z-score at birth and language delay. Conclusion: Language delay was associated with a smaller head circumference at birth in infants prenatally exposed to the Zika virus and born asymptomatic. This may indicate future learning difficulties.Zika virusChildrenCongenital infectionLanguageNeurodevelopmentinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83099https://www.arca.fiocruz.br/bitstream/icict/49089/1/license.txt586c046dcfeef936e32f0323bb9a47c0MD51ORIGINALLanguage_Patricia_Brasil_etal_INI_2021.pdfLanguage_Patricia_Brasil_etal_INI_2021.pdfapplication/pdf596782https://www.arca.fiocruz.br/bitstream/icict/49089/2/Language_Patricia_Brasil_etal_INI_2021.pdfff93e5dec1eb8324d060fe116b0650ccMD52icict/490892021-09-16 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dc.title.pt_BR.fl_str_mv Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
title Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
spellingShingle Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
Andrade, Laura Medeiros
Zika virus
Children
Congenital infection
Language
Neurodevelopment
title_short Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
title_full Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
title_fullStr Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
title_full_unstemmed Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
title_sort Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
author Andrade, Laura Medeiros
author_facet Andrade, Laura Medeiros
Meio, Maria Dalva Baker
Gomes Jr, Saint Clair
Souza, Juliana Paiva
Figueiredo, Mirza R.
Costa, Roozemeria Pereira
Brasil, Patricia
Nielsen-Saines, Karin
Brickley, Elizabeth
Moreira, Maria Elisabeth Lopes
author_role author
author2 Meio, Maria Dalva Baker
Gomes Jr, Saint Clair
Souza, Juliana Paiva
Figueiredo, Mirza R.
Costa, Roozemeria Pereira
Brasil, Patricia
Nielsen-Saines, Karin
Brickley, Elizabeth
Moreira, Maria Elisabeth Lopes
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Andrade, Laura Medeiros
Meio, Maria Dalva Baker
Gomes Jr, Saint Clair
Souza, Juliana Paiva
Figueiredo, Mirza R.
Costa, Roozemeria Pereira
Brasil, Patricia
Nielsen-Saines, Karin
Brickley, Elizabeth
Moreira, Maria Elisabeth Lopes
dc.subject.en.pt_BR.fl_str_mv Zika virus
Children
Congenital infection
Language
Neurodevelopment
topic Zika virus
Children
Congenital infection
Language
Neurodevelopment
description Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Departamento de Neonatologia. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-09-16T13:37:00Z
dc.date.available.fl_str_mv 2021-09-16T13:37:00Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE, Laura Medeiros et al. Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus. Acta paediatrica, v. 110, n. 8, p. 2375-2381, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/49089
dc.identifier.issn.pt_BR.fl_str_mv 0803-5253
dc.identifier.doi.none.fl_str_mv 10.1111/apa.15878
identifier_str_mv ANDRADE, Laura Medeiros et al. Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus. Acta paediatrica, v. 110, n. 8, p. 2375-2381, 2021.
0803-5253
10.1111/apa.15878
url https://www.arca.fiocruz.br/handle/icict/49089
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/49089/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/49089/2/Language_Patricia_Brasil_etal_INI_2021.pdf
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