Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus

Detalhes bibliográficos
Autor(a) principal: Andrade, Laura Medeiros
Data de Publicação: 2020
Outros Autores: Méio, Maria Dalva Barbosa Baker, Gomes Junior, Saint Clair dos Santos, Souza, Juliana Paiva, Figueiredo, Mirza R., Costa, Roozemeria Pereira, Brasil, Patricia, Nielsen-Saines, Karin, Brickley, Elizabeth B., Moreira, Maria Elisabeth Lopes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/49012
Resumo: 205377/Z/16/Z/the United Kingdom's Department for International Development R01 AI140718/AI/NIAID NIH HHS/United States WT_/Wellcome Trust/United Kingdom
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spelling Andrade, Laura MedeirosMéio, Maria Dalva Barbosa BakerGomes Junior, Saint Clair dos SantosSouza, Juliana PaivaFigueiredo, Mirza R.Costa, Roozemeria PereiraBrasil, PatriciaNielsen-Saines, KarinBrickley, Elizabeth B.Moreira, Maria Elisabeth Lopes2021-09-06T19:46:38Z2021-09-06T19:46:38Z2020ANDRADE, Laura Medeiros et al. Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus. Acta Paediatrica, v. 110, n. 8, p. 2375-2381, Aug. 2021.0001-6640https://www.arca.fiocruz.br/handle/icict/4901210.1111/apa.15878205377/Z/16/Z/the United Kingdom's Department for International Development R01 AI140718/AI/NIAID NIH HHS/United States WT_/Wellcome Trust/United KingdomFundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.University of California Los Angeles. Los Angeles, CA, USA.London School of Hygiene & Tropical Medicine. London, UK.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Aim: Our aim was to analyse 12-month outcomes of children who were prenatally exposed to the Zika virus and asymptomatic at birth. Methods: This was an observational, exploratory study of infants exposed to the Zika virus during gestation and born between March 2016 and April 2017 without congenital Zika syndrome. They were followed until the age of 22 months. The outcome measure was neurodevelopment at 12 months of life, which was evaluated with the Bayley Scales of Infant and Toddler Development, Third edition (Bayley-III). The scores were adjusted for maternal education and prematurity. Results: A total of 96 infants were included in the study and 35.4% scored below the normal range in at least one Bayley-III domain. The majority (91.2%) of the infants with delayed scores presented with language delay, which was not associated with the gestational age at exposure. Receptive language was more affected by exposure than expressive language (27.0% vs 19.8%). There was a direct, and significant, association between the head circumference Z-score at birth and language delay. Conclusion: Language delay was associated with a smaller head circumference at birth in infants prenatally exposed to the Zika virus and born asymptomatic. This may indicate future learning difficulties.engWiley [Commercial Publisher] Foundation, Acta Pædiatrica [Associate Organisation]FemaleHumansInfantInfant, NewbornLanguage Development DisordersMicrocephaly / etiologyPregnancyPregnancy Complications, Infectious / diagnosisZika VirusZika Virus Infection / diagnosisZika virusChildrenCongenital infectionLanguageNeurodevelopment.Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virusinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83134https://www.arca.fiocruz.br/bitstream/icict/49012/1/license.txt0ab46789d568c4ba27c7b5d29a9fe9c4MD51ORIGINALLanguage delay was associated with a smaller....pdfLanguage delay was associated with a 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dc.title.pt_BR.fl_str_mv Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
title Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
spellingShingle Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
Andrade, Laura Medeiros
Female
Humans
Infant
Infant, Newborn
Language Development Disorders
Microcephaly / etiology
Pregnancy
Pregnancy Complications, Infectious / diagnosis
Zika Virus
Zika Virus Infection / diagnosis
Zika virus
Children
Congenital infection
Language
Neurodevelopment.
title_short Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
title_full Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
title_fullStr Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
title_full_unstemmed Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
title_sort Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus
author Andrade, Laura Medeiros
author_facet Andrade, Laura Medeiros
Méio, Maria Dalva Barbosa Baker
Gomes Junior, Saint Clair dos Santos
Souza, Juliana Paiva
Figueiredo, Mirza R.
Costa, Roozemeria Pereira
Brasil, Patricia
Nielsen-Saines, Karin
Brickley, Elizabeth B.
Moreira, Maria Elisabeth Lopes
author_role author
author2 Méio, Maria Dalva Barbosa Baker
Gomes Junior, Saint Clair dos Santos
Souza, Juliana Paiva
Figueiredo, Mirza R.
Costa, Roozemeria Pereira
Brasil, Patricia
Nielsen-Saines, Karin
Brickley, Elizabeth B.
Moreira, Maria Elisabeth Lopes
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Andrade, Laura Medeiros
Méio, Maria Dalva Barbosa Baker
Gomes Junior, Saint Clair dos Santos
Souza, Juliana Paiva
Figueiredo, Mirza R.
Costa, Roozemeria Pereira
Brasil, Patricia
Nielsen-Saines, Karin
Brickley, Elizabeth B.
Moreira, Maria Elisabeth Lopes
dc.subject.mesh.pt_BR.fl_str_mv Female
Humans
Infant
Infant, Newborn
Language Development Disorders
Microcephaly / etiology
Pregnancy
Pregnancy Complications, Infectious / diagnosis
Zika Virus
Zika Virus Infection / diagnosis
topic Female
Humans
Infant
Infant, Newborn
Language Development Disorders
Microcephaly / etiology
Pregnancy
Pregnancy Complications, Infectious / diagnosis
Zika Virus
Zika Virus Infection / diagnosis
Zika virus
Children
Congenital infection
Language
Neurodevelopment.
dc.subject.en.pt_BR.fl_str_mv Zika virus
Children
Congenital infection
Language
Neurodevelopment.
description 205377/Z/16/Z/the United Kingdom's Department for International Development R01 AI140718/AI/NIAID NIH HHS/United States WT_/Wellcome Trust/United Kingdom
publishDate 2020
dc.date.issued.fl_str_mv 2020
dc.date.accessioned.fl_str_mv 2021-09-06T19:46:38Z
dc.date.available.fl_str_mv 2021-09-06T19:46:38Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE, Laura Medeiros et al. Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus. Acta Paediatrica, v. 110, n. 8, p. 2375-2381, Aug. 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/49012
dc.identifier.issn.pt_BR.fl_str_mv 0001-6640
dc.identifier.doi.none.fl_str_mv 10.1111/apa.15878
identifier_str_mv ANDRADE, Laura Medeiros et al. Language delay was associated with a smaller head circumference at birth in asymptomatic infants prenatally exposed to the Zika virus. Acta Paediatrica, v. 110, n. 8, p. 2375-2381, Aug. 2021.
0001-6640
10.1111/apa.15878
url https://www.arca.fiocruz.br/handle/icict/49012
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Wiley [Commercial Publisher] Foundation, Acta Pædiatrica [Associate Organisation]
publisher.none.fl_str_mv Wiley [Commercial Publisher] Foundation, Acta Pædiatrica [Associate Organisation]
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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