Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil

Detalhes bibliográficos
Autor(a) principal: Mann, Danielle
Data de Publicação: 2018
Outros Autores: Sant’Anna, Flávia Marinho, Schmaltz, Carolina Arana Stanis, Freitas, Dayvison Francis Saraiva, Rolla, Valeria Cavalcanti, Cavalcante, Solange Cesar, Gutierrez-Galhardo, Maria Clara
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/31140
Resumo: Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatologia Infecciosa. Rio de Janeiro, RJ, Brasil.
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spelling Mann, DanielleSant’Anna, Flávia MarinhoSchmaltz, Carolina Arana StanisFreitas, Dayvison Francis SaraivaRolla, Valeria CavalcantiCavalcante, Solange CesarGutierrez-Galhardo, Maria Clara2019-01-18T13:24:32Z2019-01-18T13:24:32Z2018MANN, Danielle et al. Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 113, n. 9, p. 1-6, July 2018.0074-0276https://www.arca.fiocruz.br/handle/icict/3114010.1590/0074-027601801841678-8060engInstituto Oswaldo CruzCutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatologia Infecciosa. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Micobacterioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Micobacterioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatologia Infecciosa. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Micobacterioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Micobacterioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatologia Infecciosa. Rio de Janeiro, RJ, Brasil.BACKGROUND: Cutaneous tuberculosis (CTB) is a rare extrapulmonary form of tuberculosis (TB). Despite the increase in the number of cases of TB and HIV, few cases of CTB have been reported. OBJECTIVE To describe CTB cases among patients with HIV infection from a cohort with tuberculosis. METHODS We describe a series of 15 CTB and HIV cases, based on secondary data from 2000 to 2016. Diagnosis was based on isolation of Mycobacterium tuberculosis in culture or clinical response to anti-tuberculous treatment associated with positive smear or histopathologic findings from affected skin or an adjacent lymph node. FINDINGS; Scrofuloderma was present in 12 (80%) patients and solitary gumma in three (20%) patients. One case of scrofuloderma was associated with papulonecrotic tuberculid. Seven (46.6%) patients had pulmonary TB. Diagnosis was based on culture in nine patients (60%). The median CD4 cell count was 262 cells/µL. All patients were cured at the end of treatment (median time 6 months). Three patients presented with immune reconstitution inflammatory syndrome. CONCLUSIONS: In this study, CTB associated with HIV infection presented as localised forms or in association with pulmonary TB. In patients with HIV who have subacute and chronic skin lesions, CTB should be considered in differential diagnosis, which may represent a good opportunity for early diagnosis of active TB.Cutaneous tuberculosisMycobacterium tuberculosisHIVAIDSImmune reconstitution inflammatory syndromeinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/31140/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Mann_Danielle_etal_INI_2018.pdfve_Mann_Danielle_etal_INI_2018.pdfapplication/pdf732770https://www.arca.fiocruz.br/bitstream/icict/31140/2/ve_Mann_Danielle_etal_INI_2018.pdfd49f7837eb1215a120fa05c9da699184MD52TEXTve_Mann_Danielle_etal_INI_2018.pdf.txtve_Mann_Danielle_etal_INI_2018.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil
title Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil
spellingShingle Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil
Mann, Danielle
Cutaneous tuberculosis
Mycobacterium tuberculosis
HIV
AIDS
Immune reconstitution inflammatory syndrome
title_short Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil
title_full Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil
title_fullStr Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil
title_full_unstemmed Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil
title_sort Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil
author Mann, Danielle
author_facet Mann, Danielle
Sant’Anna, Flávia Marinho
Schmaltz, Carolina Arana Stanis
Freitas, Dayvison Francis Saraiva
Rolla, Valeria Cavalcanti
Cavalcante, Solange Cesar
Gutierrez-Galhardo, Maria Clara
author_role author
author2 Sant’Anna, Flávia Marinho
Schmaltz, Carolina Arana Stanis
Freitas, Dayvison Francis Saraiva
Rolla, Valeria Cavalcanti
Cavalcante, Solange Cesar
Gutierrez-Galhardo, Maria Clara
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mann, Danielle
Sant’Anna, Flávia Marinho
Schmaltz, Carolina Arana Stanis
Freitas, Dayvison Francis Saraiva
Rolla, Valeria Cavalcanti
Cavalcante, Solange Cesar
Gutierrez-Galhardo, Maria Clara
dc.subject.en.pt_BR.fl_str_mv Cutaneous tuberculosis
Mycobacterium tuberculosis
HIV
AIDS
Immune reconstitution inflammatory syndrome
topic Cutaneous tuberculosis
Mycobacterium tuberculosis
HIV
AIDS
Immune reconstitution inflammatory syndrome
description Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatologia Infecciosa. Rio de Janeiro, RJ, Brasil.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-01-18T13:24:32Z
dc.date.available.fl_str_mv 2019-01-18T13:24:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MANN, Danielle et al. Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 113, n. 9, p. 1-6, July 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31140
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/0074-02760180184
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv MANN, Danielle et al. Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 113, n. 9, p. 1-6, July 2018.
0074-0276
10.1590/0074-02760180184
1678-8060
url https://www.arca.fiocruz.br/handle/icict/31140
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz
publisher.none.fl_str_mv Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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