Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/34138 |
Resumo: | Intramural Research Program of NIAID/NIH and by the Intramural-to-India grant from the US-India Cooperative research program. This study was also financed in part by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) (Finance Code 001). The work of B.B.A. was supported by a grant from NIH (U01AI115940). K.F.F. received a fellowship from the Programa Nacional de Pós-Doutorado, CAPES. D.O.S. is supported by FAPESB. C.V. is supported by the Conselho Nacional de DesenvolvimentoCientífico e Tecnológico (CNPq). |
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Narendran, GopalanSouza, Deivide Oliveira deVinhaes, Caian L.Akrami, KevanFukutani, Kiyoshi F.Banu, KesavamurthyChandrasekaran, PadmapriyadarsiniRavichandran, NarayananSereti, IriniSwaminathan, SoumyaAndrade, Bruno de Bezerril2019-07-16T13:16:41Z2019-07-16T13:16:41Z2019NARENDRAN, Gopalan et al. Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario. BMC Infectious Diseases, v. 19, p. 1-5, 2019.1471-2334https://www.arca.fiocruz.br/handle/icict/3413810.1186/s12879-019-4182-1Intramural Research Program of NIAID/NIH and by the Intramural-to-India grant from the US-India Cooperative research program. This study was also financed in part by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) (Finance Code 001). The work of B.B.A. was supported by a grant from NIH (U01AI115940). K.F.F. received a fellowship from the Programa Nacional de Pós-Doutorado, CAPES. D.O.S. is supported by FAPESB. C.V. is supported by the Conselho Nacional de DesenvolvimentoCientífico e Tecnológico (CNPq).National Institute for Research in Tuberculosis. Chennai, India.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Fundação José Silveira. Multinational Organization Network Sponsoring Translationaland Epidemiological Research Initiative. Salvador, BA, Brazil / Faculdade de Tecnologia e Ciências. Curso de Medicina. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Fundação José Silveira. Multinational Organization Network Sponsoring Translationaland Epidemiological Research Initiative. Salvador, BA, Brazil / Faculdade de Tecnologia e Ciências. Curso de Medicina. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / University of California. Division of Infectious Diseases. Department of Medicine. San Diego, USA.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Fundação José Silveira. Multinational Organization Network Sponsoring Translationaland Epidemiological Research Initiative. Salvador, BA, Brazil / Faculdade de Tecnologia e Ciências. Curso de Medicina. Salvador, BA, Brasil.Institute of Neurology. Madras Medical College.Chennai, India.National Institute for Research in Tuberculosis. Chennai, India.Government Hospital of Thoracic Medicine. Tambaram, Chennai, India.National Institutes of Health. National Institutes of Allergy and Infectious Diseases. Bethesda, MD, USA.National Institute for Research in Tuberculosis. Chennai, India.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Fundação José Silveira. Multinational Organization Network Sponsoring Translationaland Epidemiological Research Initiative. Salvador, BA, Brazil / Faculdade de Tecnologia e Ciências. Curso de Medicina. Salvador, BA, Brasil / University of Cape Town. Institute of Infectious Disease and Molecular Medicine. Wellcome Centre for Infectious Disease Research in Africa. Cape Town, South Africa / Vanderbilt University School of Medicine. Department of Medicine. Division of Infectious Diseases. Nashville, TN, USA / Universidade Salvador. Laureate Universities. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil.Tuberculosis (TB)-associated Immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response in TB patients with advanced human immunodeficiency virus coinfection, after antiretroviral therapy commencement. Case presentation: We present a rare case of a 51-year-old woman living with HIV who developed a series of TBIRIS events occurring at multiple sites sequentially, highlighting the clinical complexity in diagnosis and management. Conclusion: This case illustrates how complicated a clinical scenario of successive TB-IRIS episodes can be, in terms of clinical management.engBMCSíndrome inflamatória de reconstituição imunológicaIRISTuberculoseHIVImmune reconstitution inflammatory syndromeIRISTuberculosisHIVMultifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenarioinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/34138/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALNaredran, G. Multifocal tuberculosis...2019.pdfNaredran, G. Multifocal tuberculosis...2019.pdfapplication/pdf812496https://www.arca.fiocruz.br/bitstream/icict/34138/2/Naredran%2c%20G.%20Multifocal%20tuberculosis...2019.pdf9043362446c20e3a62ddb2c70cb0d040MD52TEXTNaredran, G. Multifocal tuberculosis...2019.pdf.txtNaredran, G. Multifocal tuberculosis...2019.pdf.txtExtracted texttext/plain21802https://www.arca.fiocruz.br/bitstream/icict/34138/3/Naredran%2c%20G.%20Multifocal%20tuberculosis...2019.pdf.txtd0cae1d728dbbaa1a0fa822bbcae6c07MD53icict/341382023-03-15 14:33:09.98oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:09Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario |
title |
Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario |
spellingShingle |
Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario Narendran, Gopalan Síndrome inflamatória de reconstituição imunológica IRIS Tuberculose HIV Immune reconstitution inflammatory syndrome IRIS Tuberculosis HIV |
title_short |
Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario |
title_full |
Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario |
title_fullStr |
Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario |
title_full_unstemmed |
Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario |
title_sort |
Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario |
author |
Narendran, Gopalan |
author_facet |
Narendran, Gopalan Souza, Deivide Oliveira de Vinhaes, Caian L. Akrami, Kevan Fukutani, Kiyoshi F. Banu, Kesavamurthy Chandrasekaran, Padmapriyadarsini Ravichandran, Narayanan Sereti, Irini Swaminathan, Soumya Andrade, Bruno de Bezerril |
author_role |
author |
author2 |
Souza, Deivide Oliveira de Vinhaes, Caian L. Akrami, Kevan Fukutani, Kiyoshi F. Banu, Kesavamurthy Chandrasekaran, Padmapriyadarsini Ravichandran, Narayanan Sereti, Irini Swaminathan, Soumya Andrade, Bruno de Bezerril |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Narendran, Gopalan Souza, Deivide Oliveira de Vinhaes, Caian L. Akrami, Kevan Fukutani, Kiyoshi F. Banu, Kesavamurthy Chandrasekaran, Padmapriyadarsini Ravichandran, Narayanan Sereti, Irini Swaminathan, Soumya Andrade, Bruno de Bezerril |
dc.subject.other.pt_BR.fl_str_mv |
Síndrome inflamatória de reconstituição imunológica IRIS Tuberculose HIV |
topic |
Síndrome inflamatória de reconstituição imunológica IRIS Tuberculose HIV Immune reconstitution inflammatory syndrome IRIS Tuberculosis HIV |
dc.subject.en.pt_BR.fl_str_mv |
Immune reconstitution inflammatory syndrome IRIS Tuberculosis HIV |
description |
Intramural Research Program of NIAID/NIH and by the Intramural-to-India grant from the US-India Cooperative research program. This study was also financed in part by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) (Finance Code 001). The work of B.B.A. was supported by a grant from NIH (U01AI115940). K.F.F. received a fellowship from the Programa Nacional de Pós-Doutorado, CAPES. D.O.S. is supported by FAPESB. C.V. is supported by the Conselho Nacional de DesenvolvimentoCientífico e Tecnológico (CNPq). |
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2019 |
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2019-07-16T13:16:41Z |
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2019-07-16T13:16:41Z |
dc.date.issued.fl_str_mv |
2019 |
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info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
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article |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
NARENDRAN, Gopalan et al. Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario. BMC Infectious Diseases, v. 19, p. 1-5, 2019. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/34138 |
dc.identifier.issn.pt_BR.fl_str_mv |
1471-2334 |
dc.identifier.doi.none.fl_str_mv |
10.1186/s12879-019-4182-1 |
identifier_str_mv |
NARENDRAN, Gopalan et al. Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario. BMC Infectious Diseases, v. 19, p. 1-5, 2019. 1471-2334 10.1186/s12879-019-4182-1 |
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https://www.arca.fiocruz.br/handle/icict/34138 |
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eng |
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